Table 1 Demographic, anthropometric and laboratory variables in all subjects

Age(y)

32.00(25.50,41.00)

35.00(28.00,41.50)

0.235

Gender(M/F)

56/35

59/32

0.645

BMI (kg/m2)

21.67 (19.81,23.91)

25.51(24.22,27.34)

< 0.0001

ALT(U/L)

15.10(10.65,20.20)

29.80(19.55,43.30)

< 0.0001

AST(U/L)

20.30(17.90,24.35)

30.90(23.90,40.20)

< 0.0001

FBG (mmol/L)

4.64(4.435,4.815)

5.06(4.725,5.675)

< 0.0001

INS (mU/L)

6.99(5.46,8.49)

12.04(8.18,15.15)

< 0.0001

CpS

1.76(1.47,2.09)

2.69(2.32,3.31)

< 0.0001

HbA1c(%)

5.30(5.20,5.50)

5.70(5.30,5.90)

< 0.0001

HOMA-IR

1.41 (1.09,1.78)

2.73(1.88,4.07)

< 0.0001

QUICK

0.67(0.62,0.72)

0.56(0.51,0.62)

< 0.0001

WBC(×10⁹)

5.44(4.77,6.09)

6.45(5.52,7.59)

< 0.0001

NEU(×10⁹)

2.95(2.51,3.59)

3.66(2.93,4.61)

< 0.0001

PLT(×10⁹)

240.00(213.00,290.00)

221.00(182.00,255.00)

< 0.0001

ALB(g/L)

48.60(47.50,50.65)

49.20(47.85,51.00)

0.199

PA (mg/L)

243.00(213.50,264.00)

286.00(269.00,329.00)

< 0.0001

Urea (mmol/L)

4.41(3.77,4.99)

4.85(4.11,5.73)

0.010

CREA (μmol/L)

58.00(50.50,67.00)

72.00(63.00,78.00)

< 0.0001

TRIG (mmol/L)

0.91(0.73,1.24)

2.09(1.58,3.07)

< 0.0001

CHOL (mmol/L)

4.45(4.04,5.02)

5.01(4.68,5.80)

< 0.0001

HDL-C (mmol/L)

1.59(1.36,1.76)

1.24(1.06,1.42)

< 0.0001

LDL-C (mmol/L)

2.53(2.03,2.83)

2.91(2.60,3.47)

< 0.0001

IL-6

1.59(1.08,2.49)

2.42(1.55,3.52)

0.002

25(OH)D

20.30(17.35,23.55)

16.40(12.95,19.80)

< 0.0001

CRP

0.16(0.13,0.23)

0.25(0.18,0.38)

< 0.0001

NFS

−3.46(−4.07,-2.80)

−2.73(− 3.32,-2.24)

< 0.0001