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Table 2 Clinical and laboratory characteristics by tertile distribution of serum IL-38 level

From: Serum interleukin-38 levels correlated with insulin resistance, liver injury and lipids in non-alcoholic fatty liver disease

Indexes T1 T2 T3 Statistical value, p p1,p2,p3
Age 32.00(24.00,41.25) 35.50(30.00,42.00) 32.50(25.75,39.00) 4.424,0.110 0.176,1.000,0.250
ALT 16.35(10.58,21.33) 19.80(13.93,31.28) 31.00(19.15,51.48) 30.437,< 0.0001 0.027,< 0.0001,0.010
AST 20.60(18.28,24.20) 23.95(18.68,30.98) 30.85(23.63,41.83) 27.725,< 0.0001 0.114,< 0.0001,0.004
PLT 233.50(194.5286.75) 236.00(204.25,272.75) 220.50(181.00,255.00) 6.337,0.042 1.000,0.080,0.095
NFS −3.40(−4.02,-2.65) − 3.01(− 3.72,-2.50) −2.86(− 3.51,-2.28) 7.982,0.018 0.272,0.015,0.756
FBG 4.65(4.44,4.89) 4.81(4.61,5.32) 4.92(4.64,5.48) 13.605,0.001 0.010,0.002,1.000
HOMA-IR 1.40(1.07,1.65) 1.88(1.43,2.50) 2.78(1.92,4.14) 50.878,< 0.0001 0.001,< 0.0001,0.002
QUICK 0.67(0.64,0.72) 0.615(0.57,0.66) 0.56(0.51,0.61) 50.878,< 0.0001 0.001,< 0.0001,0.002
CRP 0.16(0.13,0.23) 0.22(0.16,0.38) 0.23(0.15,0.35) 10.633,0.005 0.010,0.020,1.000
INS (mU/L) 6.68(5.36,7.68) 8.47(6.68,10.97) 12.69(9.21,15.63) 46.278,< 0.0001 0.004,< 0.0001,0.001
CpS 1.74(1.49,2.05) 2.22(1.83,2.75) 2.705(2.43,3.46) 46.060,< 0.0001 0.001,< 0.0001,0.003
HbA1c 5.30(5.18,5.53) 5.45(5.23,5.80) 5.60(5.30,5.90) 12.448,0.002 0.064,0.002,0.694
WBC 5.37(4.565,5.91) 6.33(5.10,7.58) 6.11(5.50,7.42) 20.186,< 0.0001 0.001,< 0.0001,1.000
NEU 2.93(2.34,3.56) 3.59(2.79,4.74) 3.44(2.78,4.30) 15.887,< 0.0001 0.001,0.006,1.000
ALB 49.55(47.68,51.23) 48.85(47.50,50.28) 49.00(47.83,51.15) 2.258,0.323 0.432,1.000,0.918
PA 247.50(222.50,271.50) 259.50(229.00,286.00) 285.00(267.00,317.00) 22.438,< 0.0001 0.552,< 0.0001,0.003
Urea 4.57(4.17,5.55) 4.41(3.79,5.25) 4.77(3.86,5.52) 1.825,0.401 0.668,1.000,0.806
CREA 59.00(52.75,70.25) 63.50(52.25,74.00) 71.50(62.50,78.00) 13.852,0.001 0.924,0.001,0.027
TRIG 0.99(0.73,1.20) 1.42(0.90,2.23) 1.96(1.41,2.98) 53.150,< 0.0001 < 0.0001,< 0.0001,0.005
CHOL 4.69(4.13,5.19) 4.67(4.11,5.44) 4.99(4.67,5.63) 7.556,0.023 1.000,0.028,0.112
HDL-C 1.54(1.36,1.76) 1.37(1.14,1.62) 1.27(1.07,1.46) 27.448,< 0.0001 0.002,< 0.0001,0.219
LDL-C 2.66(2.31,2.90) 2.63(2.25,3.33) 2.89(2.48,3.19) 5.880,0.053 1.000,0.053,0.306
BMI 21.78(19.91,24.02) 24.23 (21.32,26.26) 25.01 (23.65,27.32) 30.499,< 0.0001 0.002,< 0.0001,0.091
IL-6 1.60(0.98,2.48) 1.98(1.13,2.79) 2.43(1.55,3.40) 12.447,0.002 0.504,0.001,0.095
25(OH)D 19.80(17.20,22.65) 18.85(15.80,22.25) 15.75(12.43,19.83) 18.564,< 0.0001 0.769,< 0.0001,0.007
NF (%) 13.33 48.39 88.33 67.600,0000 < 0.0001,< 0.0001,< 0.0001
  1. p1, T1 vs T2; p2, T1 vs T3; p3, T2 vs T3. BMI Body mass index, ALT Alanine aminotransferase, AST Aspartate aminotransferase, FBG Fasting blood glucose, INS Insulin, CpS C-peptide, HbA1c Hemoglobin A1c, HOMA-IR Homoeostasis model assessment of IR, QUICK Quantitative insulin sensitivity check index, WBC White blood cell, NEU Neutrophil, PLT Platelet, ALB Albumin, PA Prealbumin, CREA Creatinine, TRIG Triglycerides, CHOL Total cholesterol, HDL-C High density liptein cholesterol, LDL-C Low-density lipoprotein cholesterol, IL-6 Interleukin-6, 25(OH) D 25 hydroxy-vitamin D, CRP C-reactive protein, NFS Non-alcoholic fatty liver disease fibrosis score. Measurement data were expressed as median (interquartile range)