Table 2 Clinical and laboratory characteristics by tertile distribution of serum IL-38 level

Age

32.00(24.00,41.25)

35.50(30.00,42.00)

32.50(25.75,39.00)

4.424,0.110

0.176,1.000,0.250

ALT

16.35(10.58,21.33)

19.80(13.93,31.28)

31.00(19.15,51.48)

30.437,< 0.0001

0.027,< 0.0001,0.010

AST

20.60(18.28,24.20)

23.95(18.68,30.98)

30.85(23.63,41.83)

27.725,< 0.0001

0.114,< 0.0001,0.004

PLT

233.50(194.5286.75)

236.00(204.25,272.75)

220.50(181.00,255.00)

6.337,0.042

1.000,0.080,0.095

NFS

−3.40(−4.02,-2.65)

− 3.01(− 3.72,-2.50)

−2.86(− 3.51,-2.28)

7.982,0.018

0.272,0.015,0.756

FBG

4.65(4.44,4.89)

4.81(4.61,5.32)

4.92(4.64,5.48)

13.605,0.001

0.010,0.002,1.000

HOMA-IR

1.40(1.07,1.65)

1.88(1.43,2.50)

2.78(1.92,4.14)

50.878,< 0.0001

0.001,< 0.0001,0.002

QUICK

0.67(0.64,0.72)

0.615(0.57,0.66)

0.56(0.51,0.61)

50.878,< 0.0001

0.001,< 0.0001,0.002

CRP

0.16(0.13,0.23)

0.22(0.16,0.38)

0.23(0.15,0.35)

10.633,0.005

0.010,0.020,1.000

INS (mU/L)

6.68(5.36,7.68)

8.47(6.68,10.97)

12.69(9.21,15.63)

46.278,< 0.0001

0.004,< 0.0001,0.001

CpS

1.74(1.49,2.05)

2.22(1.83,2.75)

2.705(2.43,3.46)

46.060,< 0.0001

0.001,< 0.0001,0.003

HbA1c

5.30(5.18,5.53)

5.45(5.23,5.80)

5.60(5.30,5.90)

12.448,0.002

0.064,0.002,0.694

WBC

5.37(4.565,5.91)

6.33(5.10,7.58)

6.11(5.50,7.42)

20.186,< 0.0001

0.001,< 0.0001,1.000

NEU

2.93(2.34,3.56)

3.59(2.79,4.74)

3.44(2.78,4.30)

15.887,< 0.0001

0.001,0.006,1.000

ALB

49.55(47.68,51.23)

48.85(47.50,50.28)

49.00(47.83,51.15)

2.258,0.323

0.432,1.000,0.918

PA

247.50(222.50,271.50)

259.50(229.00,286.00)

285.00(267.00,317.00)

22.438,< 0.0001

0.552,< 0.0001,0.003

Urea

4.57(4.17,5.55)

4.41(3.79,5.25)

4.77(3.86,5.52)

1.825,0.401

0.668,1.000,0.806

CREA

59.00(52.75,70.25)

63.50(52.25,74.00)

71.50(62.50,78.00)

13.852,0.001

0.924,0.001,0.027

TRIG

0.99(0.73,1.20)

1.42(0.90,2.23)

1.96(1.41,2.98)

53.150,< 0.0001

< 0.0001,< 0.0001,0.005

CHOL

4.69(4.13,5.19)

4.67(4.11,5.44)

4.99(4.67,5.63)

7.556,0.023

1.000,0.028,0.112

HDL-C

1.54(1.36,1.76)

1.37(1.14,1.62)

1.27(1.07,1.46)

27.448,< 0.0001

0.002,< 0.0001,0.219

LDL-C

2.66(2.31,2.90)

2.63(2.25,3.33)

2.89(2.48,3.19)

5.880,0.053

1.000,0.053,0.306

BMI

21.78(19.91,24.02)

24.23 (21.32,26.26)

25.01 (23.65,27.32)

30.499,< 0.0001

0.002,< 0.0001,0.091

IL-6

1.60(0.98,2.48)

1.98(1.13,2.79)

2.43(1.55,3.40)

12.447,0.002

0.504,0.001,0.095

25(OH)D

19.80(17.20,22.65)

18.85(15.80,22.25)

15.75(12.43,19.83)

18.564,< 0.0001

0.769,< 0.0001,0.007

NF (%)

13.33

48.39

88.33

67.600,0000

< 0.0001,< 0.0001,< 0.0001