Fig. 4

CAAT-CM effect on MDA-231 and SUM-149 cells proliferation. MDA-MB-231 and SUM-149 cells were exposed to different concentrations (25%, 50%, and 75%) of CAAT-CM from obese non-IBC and IBC patients for 24 h vs. control cells. (A) No effect was observed in MDA-MB-231 cells growth when seeded in 25%, 50% CAAT-CM, and 75% CAAT-CM downregulated cell proliferation significantly. (B) The proliferation of SUM-149 cells was downregulated significantly by the presence of 50% CAAT-CM, but it was not affected by 25% or 50% CAAT-CM. MTT was used to assess the proliferation of cells. Bar graphs represent the old change ± SEM. ^**Represents P ≤ 0.01 as determined by the Student’s t-test