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Table 5 Odds ratios (95% confidence intervals) for incident systemic embolism of sensitivity analysis (excluded 3939 participants with lipid-lowering therapy)

From: Association between lipoprotein(a) and thromboembolism in patients with non-valvular atrial fibrillation: a cross-sectional study

Lp(a) Crude OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Model 1 Model 2 Model 3
Q1 Reference Reference Reference Reference
Q2 2.02 (1.04, 3.91) 1.94 (1.00, 3.76) 1.92 (0.99, 3.73) 1.84 (0.94, 3.58)
Q3 1.84 (0.94, 3.60) 1.75 (0.89, 3.44) 1.75 (0.89, 3.43) 1.80 (0.92, 3.55)
Q4 3.04 (1.62, 5.70) 2.85 (1.51, 5.35) 2.82 (1.50, 5.29) 3.01 (1.59, 5.72)
P for trend 0.005 0.01 0.011 0.006
Log-Lp(a) 2.93 (1.78, 4.82) 2.79 (1.69, 4.61) 2.76 (1.67, 4.56) 3.21 (1.90, 5.43)
  1. Abbreviations: Lp(a) Lipoprotein(a), Log Log-transformed, OR Odds ratio, 95% CI 95% confidence interval
  2. Model 1: adjusted for sex, age, and ethnicity; Model 2: adjusted for CHA2DS2-VASc score; Model 3: adjusted for ethnicity, CHA2DS2-VASc score, anticoagulants, triglycerides, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, apolipoprotein A1, apolipoprotein B, and red-cell distribution width