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Table 2 HRs and 95% CIs of IS by tertile category of lipids

From: Association between four nontraditional lipids and ischemic stroke: a cohort study in Shanghai, China

 

Cases/N

Ischemic stroke

Model 1a

Model 2a

TC, mmol/Lb

 T1 (<  4.51)

132/11,358

1.0 (ref)

1.0 (ref)

 T2 (4.51–5.24)

144/11,427

1.05 (0.83, 1.32)

1.07 (0.84, 1.36)

 T3 (≥ 5.25)

182/11,509

1.31 (1.05, 1.65)

1.32 (1.03, 1.68)

Ptrend

 

0.015

0.022

TG, mmol/Lc

 T1 (<  1.09)

107/11,206

1.0 (ref)

1.0 (ref)

 T2 (1.09–1.66)

149/11,555

1.32 (1.03, 1.69)

1.22 (0.94, 1.57)

 T3 (≥ 1.67)

202/11,533

1.87 (1.48, 2.37)

1.58 (1.22, 2.04)

Ptrend

 

<  0.001

<  0.001

HDL-C, mmol/Lc

 T1 (<  1.25)

213/11,299

1.0 (ref)

1.0 (ref)

 T2 (1.25–1.52)

137/11,292

0.62 (0.50, 0.77)

0.64 (0.51, 0.80)

 T3 (≥ 1.53)

108/11,703

0.53 (0.42, 0.68)

0.59 (0.46, 0.76)

Ptrend

 

<  0.001

<  0.001

LDL-C, mmol/Lb

 T1 (<  2.41)

129/11,330

1.0 (ref)

1.0 (ref)

 T2 (2.41–3.06)

137/11,410

1.01 (0.79, 1.28)

1.07 (0.84, 1.36)

 T3 (≥ 3.07)

192/11,554

1.32 (1.06, 1.66)

1.36 (1.08, 1.71)

Ptrend

 

0.010

0.007

TC/HDL-C

 T1 (<  3.12)

110/11,373

1.0 (ref)

1.0 (ref)

 T2 (3.12–3.95)

124/11,446

1.05 (0.82, 1.36)

1.00 (0.77, 1.30)

 T3 (≥ 3.96)

224/11,475

1.87 (1.48, 2.35)

1.63 (1.28, 2.07)

Ptrend

 

<  0.001

<  0.001

TG/HDL-Cc

 T1 (<  0.73)

102/11,228

1.0 (ref)

1.0 (ref)

 T2 (0.73–1.29)

147/11,615

1.32 (1.03, 1.70)

1.20 (0.92, 1.55)

 T3 (≥ 1.30)

209/11,451

1.98 (1.56, 2.51)

1.65 (1.28, 2.13)

Ptrend

 

<  0.001

<  0.001

LDL-C/HDL-Cd

 T1 (<  1.70)

113/11,426

1.0 (ref)

1.0 (ref)

 T2 (1.70–2.29)

116/11,345

0.99 (0.76, 1.28)

0.93 (0.72, 1.22)

 T3 (≥ 2.30)

229/11,523

1.78 (1.42, 2.23)

1.51 (1.18, 1.92)

Ptrend

 

<  0.001

<  0.001

Non-HDL-C, mmol/L

 T1 (<  3.09)

116/11,276

1.0 (ref)

1.0 (ref)

 T2 (3.09–3.84)

146/11,548

1.18 (0.92, 1.50)

1.13 (0.89, 1.45)

 T3 (≥ 3.85)

196/11,470

1.58 (1.26, 2.00)

1.43 (1.13, 1.81)

Ptrend

 

<  0.001

0.002

  1. aModel 1: adjusted variables: age and sex; Model 2: adjusted variables: age, sex, retirement status, education level, BMI, alcohol consumption, smoking index, physical activities, hypertension, diabetes, CKD, and HUA
  2. bHDL-C and TG were additionally adjusted
  3. cLDL-C and TC were additionally adjusted
  4. dTG was additionally adjusted