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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Elevated cholesteryl ester transfer and phospholipid transfer proteins aggravated psoriasis in imiquimod-induced mouse models

Fig. 3

Imiquimod induces cytokine mRNA expression in the back skin. Back skin shaved in CETP-Tg, PLTP-Tg, and WT mice was exposed to IMQ cream treatment. After extracting RNA from back skin, (A, B) IL-17A, (C, D) IL-17F, (E, F) IL-22, (G, H) IL-23p19, (I, J) IL-1β, (K, L) IL-6, and (M, N) IFN-α expression was measured through qRT–PCR. GAPDH mRNA was used as the normalization reference. Symbols indicate the mean ± SD; n = 6/group; * P < 0.05, ** P < 0.01 vs. WT group; IMQ, imiquimod; IL, interleukin; PLTP, phospholipid transfer protein; CETP, cholesteryl ester transfer protein; WT, wild type; Tg, transgenic

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Lipids in Health and Disease

ISSN: 1476-511X