Table 2 Change in HDL-c in breast cancer patients on DOX treatment
From: Anthracycline-induced cardiotoxicity: targeting high-density lipoproteins to limit the damage?
Study | Sample | Chemotherapy regimen and duration | Results |
|---|---|---|---|
[144] | N = 1054 breast cancer patients | TAC (n = 251) Cycled every 21 days for 6 cycles CEF (n = 9) Cycled every 21 days for 6 cycles AC-T (n = 134) AC cycled every 21 days for 6 cycles followed by T cycled every 21 days for 4 cycles | ↓ HDL-c prechemotherapy vs. post chemotherapy |
[152] | N = 12 breast cancer patients | AC-P (n = 7) AC 3 times weekly for 4 weeks followed by P once weekly for 12 weeks CEF-T (n = 5) 3 times weekly for 3 weeks followed by T 3 times weekly for 3 weeks | ↓ HDL-c prechemotherapy vs. post chemotherapy |