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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Differences in lipid metabolism in acquired versus preexisting glucose intolerance during gestation: role of free fatty acids and sphingosine-1-phosphate

Fig. 1

Differences in the manifestation of impaired glucose tolerance in preIGT and aqIGT mice. Blood glucose concentrations during 120 min of oral glucose tolerance tests (OGTT) of mice with preexisting impaired glucose tolerance (preIGT; circles), impaired glucose tolerance acquired during gestation (aqIGT; triangles), and NMRI mice (squares), at time points A preconceptional (pc.) and B day 14.5 of gestation(d14.5). C Area under the curve (AUC) for blood glucose calculated by the trapezoidal rule of preIGT, aqIGT, and NMRI mice at time points pc. (white bars) and d14.5 (black bars). Data are presented as means ± SEM (n = 7–11 animals per group). *p < 0.05, ***p < 0.001, NMRI pc. vs. aqIGT pc.: 1p < 0.05, NMRI pc. vs. preIGT pc.: 2p < 0.0001. Part of the data has already been published (NMRI and preIGT datasets over a period of 0–120 min) in Grupe et al., 2020

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Lipids in Health and Disease

ISSN: 1476-511X