Table 3 Lipid profile and lipid-lowering therapy, total and according to familial hypercholesterolemia phenotype based on adjusted DLCNa Criteria
DLCNa criteria score for phenotypical FH | |||||
|---|---|---|---|---|---|
total N = 838 | unlikely FH n = 661 | possible FH n = 140 | probable FH n = 26 | definite FH n = 11 | |
Total cholesterol (mg/dL) | 169 ± 46.7 | 161 ± 41.6 | 184 ± 47.5 | 229 ± 60.9 | 252 ± 34.7 |
LDL-C (mg/dL) | 99 ± 40.8 | 91 ± 34.6 | 120 ± 44.4 | 158 ± 48.3 | 179 ± 33.5 |
Lp(a) (nmol/L) | 19 (5–72) | 18 (5–70.7) | 22 (8.3–61.2) | 15 (9–141.4) | 26 (5 -203.3) |
Lp(a) > 50 mg/dL (≈107 nmol/L) | 162 (19.3) | 123 (18.6) | 28 (20.0) | 7 (26.9) | 4 (36.4) |
HDL-C (mg/dL) | 50 ± 16.3 | 51 ± 16.3 | 50 ± 16.9 | 46 ± 10.6 | 49 ± 12.9 |
Triglycerides (mg/dL) | 144 ± 86.5 | 133 ± 78.9 | 171 ± 99 | 212 ± 84.8 | 207 ± 123.0 |
Lipid-lowering therapy (LLT) | 516 (61.6) | 370 (56.0) | 114 (81.4) | 21 (80.8) | 11 (100) |