Fig. 1

Primary indexes in obesity/obesity resistance mice. A Experimental timeline; B Average daily feed intake (ns > 0.05, HFDOR compared with HFDOP group); C Total energy intake (ns > 0.05, HFDOR compared with HFDOP group; c, P < 0.001, HFDOR compared with LFD group); D Body weight (ns > 0.05, HFDOR compared with LFD group; d, P < 0.0001, HFDOP compared with HFDOR group); E Lee’s index (ns > 0.05, HFDOR compared with LFD group; d, P < 0.0001, HFDOP compared with HFDOR group); F Picture of mice body size (16 w); G Fasting blood glucose; H - J The weight of liver, total fat (epididymal, subcutaneous, perirenal, and mesenteric fat), total visceral fat (perirenal, mesenteric, and epididymal fat); K - P The ALT, AST, LDL, HDL, TG and TC in serum (20 w) (n = 4). The values are shown as the mean ± SD. Two-group comparisons used an unpaired t test and three-group comparisons used a one-way ANOVA test. (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001) (B - J, n = 6 in the HFDOP and LFD groups, n = 12 in the HFDOR group)