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Table 1 Baseline characteristics of patients with AIH cirrhosis and noncirrhotic patients

From: Role of triglycerides as a predictor of autoimmune hepatitis with cirrhosis

 

Noncirrhosis

(n=116)

Cirrhosis

(n=80)

P values

Age (mean±SD)

51 ± 15

62 ± 12

<0.001

Female (%)

100 (86.2%)

68 (85%)

0.812

Diabetes (%)

17 (14%)

18 (23%)

0.159

Hypertension (%)

27 (23%)

15 (19%)

0.448

ANA or SMA (%)

111 (96%)

78 (98%)

0.245

ALT (U/L)

232.7 ± 198.9

100.8 ± 178.5

<0.001

AST (U/L)

212.1 ± 176.9

139.9 ± 222.2

0.013

ALP/AST

1.6 ± 2.2

4.0 ± 4.3

<0.001

TBIL (mg/dL)

46.8 (18.5,122.3)

36.1 (15.9,109.4)

0.321

GGT (U/L)

193.8 ± 180.1

121.2 ± 134.8

0.003

IgG (g/L)

23.4 (20.1,29.2)

25.3 (20.5,33.1)

0.169

IgA (g/L)

3.5 ± 1.5

4.9 ± 2.2

<0.001

IgM (g/L)

1.6 (1.0,2.5)

1.5 (1.0,2.3)

0.717

WBC (109/L)

5.6 ± 6.0

3.9 ± 2.3

0.019

RBC (1012/L)

4.9 ± 11.1

3.2 ± 0.7

0.183

HGB (g/L)

117.0 ± 19.7

100.9 ± 23.6

<0.001

INR

1.2 (1.0,1.4)

1.3 (1.1,1.5)

<0.001

PTA (%)

75.2 (62.3,94.8)

61.5 (50.0,76.0)

<0.001

PLT (109/L)

163.5 ± 72.9

89.7 ± 56.9

<0.001

NLR

2.4 ± 3.2

2.7 ± 1.9

0.485

Other autoimmune diseases

27 (23.3%)

16 (20.0%)

0.216

Simplified score system

6.2 ± 0.5

6.1 ± 0.2

0.055

TG (mmol/L)

1.5 ± 0.7

0.9 ± 0.5

<0.001

TC (mmol/L)

3.8 ± 1.7

3.0 ± 1.0

0.001

HDL-C (mmol/L)

0.8 ± 0.6

0.7 ± 0.5

0.166

LDL-C (mmol/L)

3.5 ± 15.6

1.6 ± 0.7

0.030

  1. ANA Anti-nuclear antibodies, SMA anti-smooth muscle antibodies, ALT Alanine aminotransferase, AST Aspartate aminotransferase, TBIL Total bilirubin, GGT Gamma-glutamyltranspeptidase, IgG Immunoglobulin G, IgA Immunoglobulin A, IgM Immunoglobulin M, WBC White blood cells, RBC Red blood cells, HGB Hemoglobin, INR International normalized ratio, PTA Prothrombin activity, PLT Platelets, NLR Neutrophil-lymphocyte ratio, TG Triglycerides, TC Total cholesterol, HDL-C High-density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol