Skip to main content
Fig. 2 | Lipids in Health and Disease

Fig. 2

From: WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC

Fig. 2

WY-14,643 impairs the colony formation of ccRCC cells and induces cell cycle arrest. a. Images of colony formation were captured after pretreatment with WY-14,643 in ccRCC cells. b and c. The colony formation rate was analyzed. d. An examination of the cell cycle distribution was performed in 786-O cells after specified doses of WY-14,643 were applied for 48 by BD Accuri C6 flow cytometer. e. Cell cycle distribution was quantified. f. After WY-14,643 was administered for 48 h, S-G2/M-related proteins were detected and analyzed quantitatively (n = 3). *P < 0.05, **P < 0.01. WY, WY-14,643

Back to article page