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Fig. 7 | Lipids in Health and Disease

Fig. 7

From: WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC

Fig. 7

WY-14,643 reduces lipid deposition via the PPARα/CPT1A axis. a and b. ccRCC cells were treated with GW6471, WY-14,643, or WY-14,643 plus GW6471, and CPT1A protein levels were detected and analyzed quantitatively (n = 3). c and d. Neutral lipid levels were evaluated by Nile red staining after 48 h-treatment with GW6471, WY-14,643, or WY-14,643 plus GW6471 in ccRCC cells, and images were captured. Magnification, 200x. *P < 0.05, **P < 0.01. WY, WY-14,643

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Lipids in Health and Disease

ISSN: 1476-511X