Fig. 4From: Irisin protects against obesity-related chronic kidney disease by regulating perirenal adipose tissue function in obese miceIrisin activated PRAT UCP-1, SIRT1 and HO-1 (A, B) in HFD mice in vivo (A, B) and ex vivo (C, D). *P < 0.05; n = 6/group for panel A, B; n = 3/group for panel C, D; PRAT, perirenal adipose tissue; UCP-1, Uncoupling protein 1; SIRT1, sirtuin1; HO-1, heme oxygenase-1Back to article page