Table 1 Baseline profiles classified by case group or control group

NO. (%)

9022 (66.7)

4511 (33.3)

-

Demographic data

 Women, n(%)

4225 (46.83)

2123 (47.06)

0.798 (0.46%)

 Ages (years)

69 [61,76]

69 [61,76]

0.993( 0.10%)

 BMI

23.56 [21.45,25.55]

23.62 [21.55,25.78]

0.021

 Smoker, n(%)

1300 (14.40)

642 (14.23)

0.781 (0.50%)

 Alcohol taking status, n(%)

1161 (12.86)

583 (12.92)

0.928 (0.16%)

 SBP (mmHg)

144 [130,159]

138 [125,152]

 < 0.001

 DBP (mmHg)

84 [76,92]

85 [76,94]

0.013

Medical history

 Ischemic stroke, n(%)

1647 (18.25)

1129 (25.03)

 < 0.001

 Type 2 diabetes mellitus, n(%)

1908 (21.14)

728 (16.14)

 < 0.001

 Coronary heart disease, n(%)

2431 (26.94)

1215 (26.93)

0.989 (0.24%)

 Hypertension, n(%)

5018 (55.62)

2505 (55.53)

0.922 (0.17%)

Medication on admission

 β-receptor antagonists, n(%)

2357 (26.12)

3033 (67.24)

 < 0.001

 Statin, n(%)

4312 (47.79)

2239 (49.63)

0.043

Laboratory values

 Lp(a) (mg/dL)

16.90 [8.80,33.29]

15.95 [8.57,30.70]

 < 0.001

 LDL-C (mmol/L)

2.70 [2.12,3.29]

2.35 [1.84,2.93]

 < 0.001

 ApoA (mmol/L)

1.18 [0.98,1.41]

1.09 [0.92,1.32]

 < 0.001

 ApoB (mmol/L)

0.87 [0.70,1.07]

0.77 [0.61,0.96]

 < 0.001

 HDL-C (mmol/L)

1.18 [0.97,1.44]

1.11 [0.93,1.33]

 < 0.001

 TC (mmol/L)

4.63 [3.90,5.40]

4.09 [3.41,4.81]

 < 0.001

 TG (mmol/L)

1.27 [0.92,1.86]

1.09 [0.81,1.55]

 < 0.001

 HCY (μmol/L)

13.27 [11.13,16.18]

13.78 [11.31,17.20]

 < 0.001

 Albumin (g/L)

39.48 [36.58,42.48]

37.54 [35.03,40.22]

 < 0.001

 CRP (mg/L)

3.67 [2.15,8.78]

4.03 [2.21,9.96]

 < 0.001

 Blood glucose (mmol/L)

5.58 [4.90,6.81]

5.17 [4.62,6.14]

 < 0.001

 Uric acid (μmol/L)

338.03 [278.77,408.09]

377.58 [310.25,458.53]

 < 0.001

 Serum creatinine(μmol/L)

72.00 [60.63,85.64]

78.00 [65.21,91.99]

 < 0.001