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Table 3 Associations of different lipid measures as continuous variables and in quintiles with total occlusion

From: Associations of lipid measures with total occlusion in patients with established coronary artery disease: a cross-sectional study

 

Number (%)

Model 1

Model 2

Model 3

 

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

TC, mmol/L

       

Per SD increase

—

1.050 (1.003, 1.099)

0.036

1.065 (1.017, 1.116)

0.007

1.072 (1.023, 1.123)

0.004

Q1: < 3.31

391 (19.54)

1.0 (Ref.)

—

1.0 (Ref.)

—

1.0 (Ref.)

—

Q2: 3.31 ≤ TC < 3.81

343 (17.19)

0.855 (0.728, 1.004)

0.056

0.868 (0.739, 1.019)

0.084

0.884 (0.752, 1.039)

0.136

Q3: 3.81 ≤ TC < 4.32

373 (18.76)

0.951 (0.812, 1.114)

0.533

0.980 (0.836, 1.148)

0.803

0.980 (0.835, 1.150)

0.803

Q4: 4.32 ≤ TC < 5.03

370 (18.25)

0.919 (0.785, 1.077)

0.297

0.958 (0.817, 1.123)

0.593

0.975 (0.830, 1.145)

0.756

Q5: ≥ 5.03

402 (20.18)

1.041 (0.891, 1.216)

0.612

1.090 (0.931, 1.276)

0.285

1.111 (0.948, 1.303)

0.195

p for trend

—

0.401

—

0.144

—

0.097

—

TG, mmol/L

       

Per SD increase

—

1.043 (0.998, 1.089)

0.060

1.028 (0.983, 1.075)

0.223

1.016 (0.971, 1.065)

0.488

Q1: < 1.06

361 (17.95)

1.0 (Ref.)

—

1.0 (Ref.)

—

1.0 (Ref.)

—

Q2: 1.06 ≤ TG < 1.37

338 (17.15)

0.946 (0.803, 1.114)

0.506

0.938 (0.797, 1.106)

0.447

0.908 (0.769, 1.071)

0.251

Q3: 1.37 ≤ TG < 1.71

388 (19.23)

1.088 (0.928, 1.275)

0.298

1.080 (0.920, 1.267)

0.384

1.024 (0.871, 1.205)

0.770

Q4: 1.71 ≤ TG < 2.28

382 (19.01)

1.073 (0.915, 1.258)

0.385

1.053 (0.896, 1.237)

0.531

0.997 (0.847, 1.174)

0.973

Q5: ≥ 2.28

410 (20.56)

1.183 (1.011, 1.385)

0.036

1.138 (0.969, 1.336)

0.116

1.068 (0.906, 1.258)

0.436

p for trend

—

0.011

—

0.044

—

0.234

—

LDL-c, mmol/L

       

Per SD increase

—

1.104 (1.047, 1.165)

 < 0.001

1.114 (1.056, 1.176)

 < 0.001

1.119 (1.060, 1.182)

 < 0.001

Q1: < 1.76

355 (17.84)

1.0 (Ref.)

—

1.0 (Ref.)

—

1.0 (Ref.)

—

Q2: 1.76 ≤ LDL-c < 2.16

375 (18.66)

1.056 (0.900, 1.240)

0.503

1.062 (0.904, 1.247)

0.463

1.065 (0.905, 1.252)

0.448

Q3: 2.16 ≤ LDL-c < 2.59

360 (18.12)

1.019 (0.867, 1.198)

0.819

1.036 (0.881, 1.218)

0.671

1.045 (0.887, 1.231)

0.599

Q4: 2.59 ≤ LDL-c < 3.19

377 (18.64)

1.055 (0.899, 1.238)

0.514

1.077 (0.917, 1.265)

0.367

1.084 (0.921, 1.276)

0.331

Q5: ≥ 3.19

412 (20.67)

1.200 (1.025, 1.405)

0.023

1.232 (1.051, 1.444)

0.010

1.243 (1.059, 1.460)

0.008

p for trend

—

0.042

—

0.017

—

0.013

—

Non-HDL-c, mmol/L

       

Per SD increase

—

1.110 (1.059, 1.163)

 < 0.001

1.113 (1.061, 1.167)

 < 0.001

1.113 (1.061, 1.168)

 < 0.001

Q1: < 2.30

353 (17.50)

1.0 (Ref.)

—

1.0 (Ref.)

—

1.0 (Ref.)

—

Q2: 2.30 ≤ nHDL-c < 2.78

375 (19.02)

1.107 (0.943, 1.300)

0.216

1.106 (0.942, 1.300)

0.220

1.090 (0.926, 1.282)

0.300

Q3: 2.78 ≤ nHDL-c < 3.28

347 (17.09)

0.972 (0.826, 1.144)

0.732

0.982 (0.834, 1.157)

0.831

0.965 (0.818, 1.139)

0.674

Q4: 3.28 ≤ nHDL-c < 3.96

381 (19.24)

1.123 (0.957, 1.318)

0.155

1.132 (0.963, 1.330)

0.132

1.120 (0.952, 1.319)

0.172

Q5: ≥ 3.96

423 (21.11)

1.261 (1.078, 1.476)

0.004

1.275 (1.088, 1.494)

0.003

1.263 (1.076, 1.484)

0.004

p for trend

—

0.007

—

0.005

—

0.006

—

Lp(a), mg/dL

       

Per SD increase

—

1.003 (1.001, 1.005)

0.002

1.003 (1.002, 1.005)

 < 0.001

1.003 (1.002, 1.005)

 < 0.001

Q1: < 6.27

323 (16.14)

1.0 (Ref.)

—

1.0 (Ref.)

—

1.0 (Ref.)

—

Q2: 6.27 ≤ lp(a) < 13.08

363 (18.15)

1.152 (0.977, 1.358)

0.092

1.177 (0.998, 1.389)

0.052

1.168 (0.989, 1.379)

0.068

Q3: 13.08 ≤ lp(a) < 25.21

387 (19.34)

1.246 (1.059, 1.466)

0.008

1.270 (1.079, 1.496)

0.004

1.263 (1.072, 1.489)

0.005

Q4: 25.21 ≤ lp(a) < 48.42

400 (20.00)

1.299 (1.105, 1.527)

0.002

1.331 (1.131, 1.565)

0.001

1.340 (1.138, 1.579)

0.001

Q5: ≥ 48.42

406 (20.29)

1.322 (1.125, 1.554)

0.001

1.391 (1.183, 1.637)

 < 0.001

1.384 (1.175, 1.631)

0.001

p for trend

—

 < 0.001

—

 < 0.001

—

 < 0.001

—

ApoB, g/L

       

Per SD increase

—

1.603 (1.318, 1.949)

 < 0.001

1.612 (1.323, 1.964)

 < 0.001

1.605 (1.313, 1.961)

 < 0.001

Q1: < 0.63

340 (17.03)

1.0 (Ref.)

—

1.0 (Ref.)

—

1.0 (Ref.)

—

Q2: 0.63 ≤ apoB < 0.75

369 (18.21)

1.085 (0.923, 1.277)

0.323

1.075 (0.914, 1.265)

0.384

1.078 (0.915, 1.270)

0.369

Q3: 0.75 ≤ apoB < 0.86

336 (17.68)

1.047 (0.887, 1.236)

0.587

1.041 (0.881, 1.230)

0.636

1.039 (0.878, 1.229)

0.658

Q4: 0.86 ≤ apoB < 1.02

391 (18.93)

1.138 (0.970, 1.336)

0.113

1.140 (0.970, 1.340)

0.111

1.126 (0.956, 1.325)

0.155

Q5: ≥ 1.02

443 (21.99)

1.373 (1.174, 1.607)

 < 0.001

1.375 (1.173, 1.611)

 < 0.001

1.373 (1.170, 1.613)

 < 0.001

p for trend

—

 < 0.001

—

 < 0.001

—

 < 0.001

—

Non-HDL-c/HDL-c

       

Per SD increase

—

1.168 (1.129, 1.208)

 < 0.001

1.149 (1.110, 1.190)

 < 0.001

1.135 (1.095, 1.176)

 < 0.001

Q1: < 2.17

288 (14.38)

1.0 (Ref.)

—

1.0 (Ref.)

—

1.0 (Ref.)

—

Q2: 2.17 ≤ ratio < 2.74

328 (16.37)

1.165 (0.981, 1.384)

0.081

1.136 (0.956, 1.350)

0.148

1.107 (0.930, 1.318)

0.252

Q3: 2.74 ≤ ratio < 3.39

398 (19.92)

1.481 (1.254, 1.749)

 < 0.001

1.429 (1.209, 1.689)

 < 0.001

1.380 (1.165, 1.635)

 < 0.001

Q4: 3.39 ≤ ratio < 4.27

391 (19.57)

1.449 (1.226, 1.712)

 < 0.001

1.390 (1.175, 1.644)

 < 0.001

1.338 (1.129, 1.587)

 < 0.001

Q5: ≥ 4.27

474 (23.70)

1.850 (1.573, 2.175)

 < 0.001

1.727 (1.465, 2.037)

 < 0.001

1.619 (1.368, 1.916)

 < 0.001

p for trend

—

 < 0.001

—

 < 0.001

—

 < 0.001

—

ApoB/apoA-1

       

Per SD increase

—

3.030 (2.419, 3.795)

 < 0.001

2.762 (2.196, 3.475)

 < 0.001

2.590 (2.049, 3.274)

 < 0.001

Q1: < 0.47

288 (14.31)

1.0 (Ref.)

—

1.0 (Ref.)

—

1.0 (Ref.)

—

Q2: 0.47 ≤ ratio < 0.57

326 (16.48)

1.181 (0.994, 1.403)

0.058

1.145 (0.963, 1.361)

0.125

1.126 (0.946, 1.341)

0.181

Q3: 0.57 ≤ ratio < 0.66

356 (17.73)

1.290 (1.089, 1.528)

0.003

1.243 (1.049, 1.474)

0.012

1.209 (1.018, 1.435)

0.030

Q4: 0.66 ≤ ratio < 0.79

410 (20.43)

1.537 (1.303, 1.813)

 < 0.001

1.468 (1.243, 1.734)

 < 0.001

1.427 (1.206, 1.688)

 < 0.001

Q5: ≥ 0.79

499 (24.97)

1.993 (1.697, 2.340)

 < 0.001

1.871 (1.590, 2.202)

 < 0.001

1.787 (1.514, 2.109)

 < 0.001

p for trend

—

 < 0.001

—

 < 0.001

—

 < 0.001

—

  1. Model 1 was the crude model. Model 2 was adjusted for sex and age. Model 3 was adjusted for sex, age, body mass index, hypertension, diabetes, prior myocardial infarction, prior percutaneous coronary intervention, smoking history, and admission presentation
  2. OR odds ratio, CI confidence interval, SD standard deviation, Q quintile, Ref reference