Obesity promotes lipid accumulation in lymph node metastasis of gastric cancer: a retrospective case‒control study

Table 4 Associations of continuous variables (LP (a), BMI, and LDL-C) with lymph node metastasis in subgroup analysis

Variables	LP (a) ^a		BMI ^b		LDL-C ^c
Variables	OR (95% CI) ^†	P ^†	OR (95% CI) ^†	P ^†	OR (95% CI) ^†	P ^†
Age (years)
≤ 65	0.99 (0.98–1.00)	0.256	1.47 (0.94–2.30)	0.092	0.99 (0.98–1.00)	0.256
> 65	1.02 (1.01–1.03)	0.022	1.57 (0.90–2.73)	0.109	1.10 (0.92–1.32)	0.304
Sex
Male	1.00 (0.99–1.01)	0.296	1.69 (1.12–2.55)	0.013	1.04 (0.90–1.19)	0.602
Female	1.00 (0.98–1.02)	0.992	1.16 (0.62–2.18)	0.640	1.27 (1.02–1.59)	0.037
Location
Upper	0.99 (0.97–1.01)	0.390	1.21 (0.52–2.78)	0.662	1.25 (0.96–1.64)	0.094
Middle	0.99 (0.98–1.01)	0.608	1.51 (0.82–2.79)	0.189	1.10 (0.91–1.33)	0.340
Lower	1.02 (1.01–1.03)	0.031	1.69 (1.03–2.77)	0.037	1.08 (0.89–1.32)	0.430
T stage
T1 + T2	1.01 (1.00–1.02)	0.058	1.46 (0.92–2.32)	0.105	1.14 (0.96–1.35)	0.132
T3 + T4	1.00 (0.98–1.01)	0.474	1.44 (0.87–2.38)	0.160	1.13 (0.95–1.34)	0.171
Grade
G2	1.01 (0.99–1.03)	0.249	0.85 (0.39–1.89)	0.696	1.13 (0.88–1.44)	0.339
G2-3	1.01 (0.99–1.02)	0.279	2.43 (1.32–4.46)	0.004	1.04 (0.84–1.30)	0.692
G3	0.99 (0.98–1.01)	0.399	1.29 (0.75–2.22)	0.366	1.21 (0.99–1.48)	0.055

OR odds ratio, CI confidence interval
^† Adjusted for TG, TC, HDL-C, LDL-C, LP (a), THR, BMI, age, sex, location, grade, T stage, tumor size, PNI, LVI, Lauren classification, and ELN (excluding the stratified factor in each stratum)
^a Odds ratios reported for a 10 mg/L increase in LP (a)
^b Odds ratios reported for a 5 kg/m² increase
^c Odds ratios reported for a 0.1 mmol/L increase in LDL-C
The significant results are in bold

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