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Table 2 HDL-C effects among different BMI subgroups on all-cause mortality and MACCE

From: BMI modifies HDL-C effects on coronary artery bypass grafting outcomes

HDL

Crude

Adjusted

Mortality HR (95%CI)

P value

MACCE HR (95%CI)

P value

Mortality HR (95%CI)

P value

MACCE HR (95%CI)

P value

18.5 ≤ BMI < 25 (normal)

HDL < 40

1.032 (0.882, 1.209)

0.692

1.150 (1.024, 1.290)

0.018

0.988 (0.842, 1.160)

0.885

1.164 (1.035, 1.310)

0.012

40 < HDL < 60

Reference

Reference

Reference

Reference

HDL > 60

0.537 (0.276, 1.046)

0.068

0.916 (0.623, 1.346)

0.655

0.471 (0.242, 0.919)

0.027

0.850 (0.578, 1.251)

0.410

25 ≤ BMI < 30 (overweight)

HDL < 40

1.013 (0.884, 1.161)

0.854

1.079 (0.981, 1.186)

0.119

0.999 (0.868, 1.150)

0.986

1.084 (0.983, 1.196)

0.106

40 < HDL < 60

Reference

Reference

 

Reference

Reference

HDL > 60

0.683 (0.407, 1.145)

0.148

0.858 (0.618, 1.190)

0.358

0.642 (0.383, 0.981)

0.007

0.835 (0.601, 1.159)

0.281

30 ≤ BMI < 35 (obese)

HDL < 40

1.225 (0.974, 1.539

0.082

1.057 (0.914, 1.222)

0.456

1.205 (0.981, 1.530)

0.081

1.123 (1.021, 1.278)

0.012

40 < HDL < 60

Reference

Reference

Reference

Reference

HDL > 60

1.063 (0.519, 2.178)

0.867

0.896 (0.549, 1.462)

0.661

1.159 (0.564, 2.384)

0.688

0.906 (0.555, 1.481)

0.695

  1. HDL-C High-density lipoprotein cholesterol, BMI Body mass index, MACCE Major adverse cardio-cerebrovascular events