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Table 2 Associations between blood lipid biomarkers and 10-year CVD incidence in the total study population (n = 2020)

From: Long-term prognostic value of LDL-C, HDL-C, lp(a) and TG levels on cardiovascular disease incidence, by body weight status, dietary habits and lipid-lowering treatment: the ATTICA epidemiological cohort study (2002–2012)

 

10-year CVD incidence

RR

95%CI

P value

Adj. R2

Harrell’s C

cNRI

TC, mg/dL

1.003

0.999, 1.007

0.111

17.4%

0.205

10.4%

LDL-C, mg/dL

1.002

0.998, 1.007

0.379

17.6%

0.739

11.1%

HDL-C, mg/dL

0.983

0.967, 1.000

0.050

17.8%

0.521

12.6%

TG, mg/dL

1.002

1.001, 1.003

0.012

17.3%

0.707

5.0%

Lp(a), mg/dL

1.003

0.997, 1.010

0.251

17.6%

0.562

6.7%

  1. The results are presented as relative risks (RRs) with their 95% confidence intervals (CIs), as derived from multivariate Cox proportional hazard models
  2. All models were adjusted for age, sex, body mass index, smoking status, MedDietScore, physical activity level, presence of hypercholesterolemia, hypertension and diabetes mellitus at baseline, use of lipid-lowering medication, and family history of cardiovascular disease
  3. cNRI Continuous net reclassification improvement, CVD Cardiovascular disease, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol; Lp(a) Lipoprotein(a), TC Total cholesterol, TG Triglycerides
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Lipids in Health and Disease

ISSN: 1476-511X