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Table 1 Comparison of participant characteristics between the SCH group and the control group

From: Assessment of the relationship between subclinical hypothyroidism and blood lipid profile: reliable or not?

 

Total (N = 11,512)

Control group (N = 10,827)

SCH group(N = 685)

Statistical value, P value

Age(years)

49.05 ± 8.88

48.94 ± 8.83

50.82 ± 9.42

t = 5.398, P < 0.001*

Sex (%)

   

χ2 = 164.581,P < 0.001*

 Male

8234(71.53)

7891(72.88)

343(50.07)

 

 female

3278(28.47)

2936(27.12)

342(49.93)

 

Smoke

   

χ2 = 80.772, P < 0.001*

 No

6768(58.79)

6253(57.75)

515(75.18)

 

 Yes

4744(41.21)

4574(42.25)

170(24.82)

 

Thyroid nodule

   

χ2 = 9.764, P = 0.002*

 No

5252(45.62)

4979(45.99)

273(39.85)

 

 Yes

6260(54.38)

5848(54.01)

412(60.15)

 

Fatty liver

   

χ2 = 9.179, P = 0.002*

 NO

4006(34.80)

3731(34.46)

275(40.15)

 

 Yes

7506(65.20)

7096(65.54)

410(59.85)

 

Hypertension

   

χ2 = 0.224, P = 0.636

 NO

7044(61.19)

6619(61.63)

425(62.04)

 

 Yes

4468(38.81)

4208(38.87)

260(37.96)

 

SBP (mmHg)

121.53 ± 16.54

121.56 ± 16.48

121.36 ± 17.41

Z = 0.366, P = 0.714

DBP (mmHg)

79.49 ± 11.27

79.51 ± 11.27

79.22 ± 11.25

Z = 0.597, P = 0.550

BMI (kg/m2)

25.25 ± 3.29

25.28 ± 3.29

24.88 ± 3.24

Z = 2.914, P = 0.004*

HGB (g/L)

147.53 ± 14.73

147.79 ± 14.69

143.35 ± 14.71

Z = 8.264, P < 0.001*

TC (mmol/L)

4.70 ± 0.89

4.69 ± 0.89

4.87 ± 0.92

Z = 4.417, P < 0.001*

TG (mmol/L)

1.76 ± 1.38

1.75 ± 1.36

1.76 ± 1.75

Z = 0.627, P = 0.531

LDL-C (mmol/L)

3.03 ± 0.79

3.02 ± 0.79

3.13 ± 0.79

Z = 3.505, P < 0.001*

HDL-C (mmol/L)

1.25 ± 0.34

1.24 ± 0.34

1.29 ± 0.33

Z = 4.482, P < 0.001*

FBG (mmol/L)

5.67 ± 1.24

5.67 ± 1.25

5.56 ± 1.06

Z = 2.343, P = 0.019*

Hcy(μmol/L)

12.27 ± 7.70

12.29 ± 7.79

11.85 ± 5.90

Z = 2.409, P = 0.041*

UA(μmol/L)

345.97 ± 86.04

347.01 ± 85.91

329.54 ± 86.29

Z = 5.565,P < 0.001*

HbA1c(%)

5.77 ± 0.75

5.77 ± 0.76

5.75 ± 0.71

Z = 0.660, P = 0.509

  1. List of Abbreviations: SCH subclinical hypothyroidism, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, HGB hemoglobin determination, TC total cholesterol, TG triglyceride, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, FBG fasting blood glucose, Hcy homocysteine, UA blood uric acid, HbA1c hemoglobin A1c
  2. *Significantly different between the two groups, (P < 0.05)