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Table 4 Recomparison of participant characteristics among the three groups (N = 2739)

From: Assessment of the relationship between subclinical hypothyroidism and blood lipid profile: reliable or not?

 

Strict control group (n = 2054)

Mild SCH (n = 650)

Severe SCH (n = 35)

Statistical value, P value

Age(years)

50.84 ± 9.39

50.79 ± 9.52

51.49 ± 7.39

χ2 = 0.158,P = 0.924

Sex (%)

   

χ2 = 0.553,P = 0.758

 Male

1028(50.05)

323(49.69)

20(57.14)

 

 female

1026(49.95)

327(50.31)

15(42.86)

 

Smoke

   

χ2 = 1.989,P = 0.370

 No

1492(72.64)

492(75.69)

23(65.71)

 

 Yes

562(27.36)

158(24.31)

12(34.29)

 

Thyroid nodule

   

χ2 = 0.184, P = 0.912

 No

841(40.94)

259(39.85)

14(40.00)

 

 Yes

1213(59.06)

391(60.15)

21(60.00)

 

Fatty liver

   

χ2 = 0.011, P = 0.995

 NO

830(40.41)

261(40.15)

14(40.00)

 

 Yes

1224(59.59)

389(59.85)

21(60.00)

 

Hypertension

   

χ2 = 0.469, P = 0.791

 NO

1298(63.19)

405(62.31)

20(57.14)

 

 Yes

756(36.81)

245(37.69)

15(42.86)

 

SBP (mmHg)

121.28 ± 17.26

121.40 ± 17.41

120.63 ± 19.87

χ2 = 0.180, P = 0.914

DBP (mmHg)

78.72 ± 11.33

79.26 ± 11.20

80.34 ± 12.11

χ2 = 1.916, P = 0.384

BMI (kg/m2)

24.85 ± 3.36

24.84 ± 3.18

25.52 ± 4.30

χ2 = 0.352, P = 0.838

HGB (g/L)

143.01 ± 15.42

143.09 ± 14.59

148.14 ± 16.22

χ2 = 2.598, P = 0.273

TC (mmol/L)

4.76 ± 0.88

4.86 ± 0.92

4.96 ± 0.94

χ2 = 5.711, P = 0.057

TG (mmol/L)

1.59 ± 1.12

1.77 ± 1.78

1.51 ± 0.86

χ2 = 6.527, P = 0.038 †

LDL-C (mmol/L)

3.07 ± 0.78

3.13 ± 0.79

3.26 ± 0.91

χ2 = 4.186, P = 0.123

HDL-C (mmol/L)

1.31 ± 0.35

1.29 ± 0.33

1.36 ± 0.26

χ2 = 3.919, P = 0.141

FBG (mmol/L)

5.64 ± 1.18

5.56 ± 1.07

5.57 ± 0.83

χ2 = 2.178, P = 0.337

Hcy(μmol/L)

11.42 ± 5.53

11.765.74

13.338.21

χ2 = 3.995, P = 0.136

UA(μmol/L)

321.81 ± 84.55

329.69 ± 86.82

326.68 ± 76.82

χ2 = 4.186, P = 0.123

HbA1c(%)

5.79 ± 0.74

5.75 ± 0.72

5.74 ± 0.55

χ2 = 0.703, P = 0.704

  1. List of Abbreviations: SCH subclinical hypothyroidism, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, HGB hemoglobin determination, TC total cholesterol, TG triglyceride, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, FBG fasting blood glucose, Hcy homocysteine, UA blood uric acid, HbA1c hemoglobin A1c
  2. †: Significantly different among the three group by the Kruskal-Wallis rank tests, (P < 0.05)