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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway

Fig. 1

Adipocytes wasting is observed in mouse model of lung cancer and CRC cachexia. A-D The body weights growth curves of mice for 22 days in the LLC-TB, C26-TB and CN groups. Weight of the tumor free body was also assessed for mice (B), eWAT (C) and iWAT (D) in the CN and TB groups (n = 5), respectively. E-F H&E staining of eWAT, iWAT and the CSA of adipocytes in adipose tissues were analyzed by χ2 analysis (n = 5). G Levels of glycerol release in mouse serum in the above groups. H-I Western blot of PGC1α and UCP1 proteins in the iWAT of CN and LLC-TB groups with densitometric analyses. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Lipids in Health and Disease

ISSN: 1476-511X