Table 1 Sex-specific characteristics, serum lipids, and hemostatic factors (means ± SDs or median and IQR): the population-based KORA-Fit Study
|  | Participants (n = 805) | Units | Ref. values | MEN (n = 378) | WOMEN (n = 427) | p value |
|---|---|---|---|---|---|---|
Age | 805 (0 missings) | years | Â | 63.1 (5.8) | 63.1 (5.5) | 0.942 |
BMI | 805 (0 missings) | kg/m2 | Â | 28.4 (4.2) | 27.4 (5.2) | 0.003 |
Systolic blood pressure | 803 (2 missings) | mmHg |  | 130.2 (15.3) | 120.2 (16.5) | < 0.001 |
Education | 805 (0 missings) | education ≤10 yrs |  | 118 (31.2) | 171 (40.0) | 0.010 |
|  |  | education > 10 yrs |  | 260 (68.8) | 256 (60.0) |  |
Diabetes | 803 (2 missings) | yes | Â | 36 (9.5) | 33 (7.7) | 0.381 |
| Â | Â | no | Â | 342 (90.5) | 392 (91.8) | Â |
Physical activity | 805 (0 missings) | yes | Â | 261 (69.0) | 304 (71.2) | 0.537 |
| Â | Â | no | Â | 117 (31.0) | 123 (28.8) | Â |
Smoking status | 805 (0 missings) | Smoker |  | 56 (14.8) | 54 (12.6) | < 0.001 |
| Â | Â | Ex smoker | Â | 192 (50.8) | 163 (38.2) | Â |
| Â | Â | Never smoker | Â | 130 (34.4) | 210 (49.2) | Â |
Alcohol intake | 804 (1 missing) | g/day | Â | 5.7 (0.0; 21.5) | 6.6 (0.0; 22.9) | 0.147 |
aPTT | 803 (2 missings) | sec | 26–36  | 31.5 (3.4) | 0.6 (3.2) | < 0.001 |
Antithrombin III activity | 804 (1 missing) | % | 83–118 | 99.4 (10.3) | 104.9 (10.4) | < 0.001 |
Fibrinogen | 758 (47 missings) | mg/dl | 210–400 | 298.9 (62.8) | 305.2 (60.2) | 0.163 |
D-dimers | 805 (0 missing) | ng/ml | ≤500  | 408.0 (314.8; 563.0) | 405.5 (306.0; 554.0) | 0.642 |
Protein C activity | 805 (0 missing) | % | 70–140 | 119.9 (17.4) | 127.9 (17.5) | < 0.001 |
Protein S activity | 789 (16 missings) | % | m 73–130, w 52–126 | 137.1 (38.5) | 120.9 (27.6) | < 0.001 |
Factor VIII activity | 804 (1 missing) | % | 70–150 | 122.6 (36.9) | 124.9 (34.4) | 0.371 |
Total cholesterol | 805 (0 missing) | mg/dl | normal 0–200 | 190 (50.3) | 132 (30.9) | < 0.001 |
high > 200 | 188 (49.7) | 295 (69.1) | ||||
HDL cholesterol | 805 (0 missing) | mg/dl | low ≤45 | 111 (29.4) | 26 (6.1) | < 0.001 |
normal > 45 | 267 (70.6) | 401 (93.9) | ||||
LDL cholesterol (Friedewald) | 760 (45 missings) | mg/dl | normal ≤160 | 319 (86.7) | 354 (84.1) | 0.315 |
high > 160 | 49 (13.3) | 67 (15.9) | ||||
Non-HDL cholesterol | 805 (0 missing) | mg/dl | normal ≤130 | 145 (38.4) | 137 (32.1) | 0.065 |
high > 130 | 233 (61.6) | 290 (67.9) | ||||
Triglycerides | 805 (0 missing) | mg/dl | normal 0–200 | 325 (86.0) | 394 (92.3) | 0.004 |
high > 200 | 53 (14.0) | 33 (7.7) |