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Table 2 Results of the linear regression (ß value, 95% CI, p value) on the associations between serum lipids and coagulation parameters in both sexes (KORA-Fit)

From: Sex-specific associations between serum lipids and hemostatic factors: the cross-sectional population-based KORA-fit study

 

Total cholesterol mg/dl

HDL cholesterol mg/dl

LDL cholesterol (Fried) mg/dl

non-HDL cholesterol mg/dl

Triglycerides mg/dl

aPTT

−0.002 (− 0.009, 0.004)

−0.022 (− 0.037, − 0.006)

0.001 (− 0.006, 0.008)

0.002 (− 0.005, 0.008)

0.001 (− 0.003, 0.005)

0.523

0.005

0.822

0.584

0.571

AT III

0.039 (0.019, 0.059)

0.023 (− 0.024, 0.070)

0.037 (0.015, 0.059)

0.034 (0.014, 0.053)

0.002 (−0.008, 0.011)

< 0.001

0.334

< 0.001

< 0.001

0.753

Fibrinogen

−0.015 (− 0.137, 0.106)

− 0.505 (− 0.785, − 0.225)

0.084 (− 0.051, 0.219)

0.076 (− 0.044, 0.196)

0.001 (− 0.068, 0.071)

0.804

< 0.001

0.220

0.212

0.975

D-dimers

0.515 (− 0.299, 1.329)

−1.083 (−2.979, 0.813)

0.625 (− 0.242, 1.491)

0.698 (− 0.107, 1.501)

0.151 (− 0.244, 0.546)

0.215

0.263

0.157

0.089

0.453

Protein C

0.156 (0.124, 0.189)

0.064 (−0.016, 0.144)

0.139 (0.102, 0.175)

0.141 (0.108, 0.173)

0.033 (0.016, 0.049)

< 0.001

0.118

< 0.001

< 0.001

< 0.001

Protein S

0.150 (0.084, 0.215)

0.012 (−0.141, 0.165)

0.125 (0.053, 0.196)

0.143 (0.078, 0.208)

0.061 (0.029, 0.092)

< 0.001

0.876

< 0.001

< 0.001

< 0.001

Factor VIII

0.069 (0.001, 0.137)

0.068 (−0.091, 0.227)

0.055 (−0.020, 0.131)

0.055 (− 0.012, 0.123)

0.019 (− 0.014, 0.052)

0.046

0.400

0.150

0.106

0.260

  1. Participants with anticoagulative medication were excluded from the linear regression analyses
  2. Independent variables: lipid parameters (continuously). Adjusted for age, sex, BMI, education (≤/> 10 years), diabetes, smoking (yes/no/never), systolic blood pressure, and intake of antihypertensive medication
  3. aPTT activated partial prothrombin time