Sex-specific associations between serum lipids and hemostatic factors: the cross-sectional population-based KORA-fit study

Table 4 Results of the linear regression (ß value, 95% CI, p value) on the associations between serum lipids and coagulation parameters in women (KORA-Fit)

	Total cholesterol mg/dl	HDL cholesterol mg/dl	LDL cholesterol mg/dl	Non-HDL cholesterol mg/dl	Triglycerides mg/dl
aPTT	0.004 (−0.004, 0.013)	−0.013 (− 0.032, 0.005)	0.007 (− 0.002, 0.017)	0.007 (− 0.001, 0.016)	0.003 (− 0.003, 0.009)
aPTT	0.313	0.155	0.129	0.094	0.294
AT III	0.065 (0.038, 0.092)	0.053 (−0.007, 0.113)	0.056 (0.026, 0.087)	0.054 (0.026, 0.081)	0.009 (−0.010, 0.028)
AT III	< 0.001	0.081	< 0.001	< 0.001	0.360
Fibrinogen	0.050 (−0.110, 0.211)	−0.401 (− 0.739, − 0.063)	0.164 (− 0.016, 0.345)	0.141 (− 0.020, 0.301)	−0.027 (− 0.136, 0.083)
Fibrinogen	0.538	0.020	0.074	0.086	0.631
D-dimers	0.474 (−0.482, 1.430)	0.214 (−1.845, 2.272)	0.621 (−0.446, 1.687)	0.428 (− 0.528, 1.385)	−0.164 (− 0.830, 0.502)
D-dimers	0.330	0.838	0.253	0.379	0.629
Protein C	0.180 (0.137, 0.223)	0.093 (−0.007, 0.193)	0.160 (0.110, 0.209)	0.160 (0.116, 0.204)	0.059 (0.027, 0.091
Protein C	< 0.001	0.069	< 0.001	< 0.001	< 0.001
Protein S	0.083 (0.009, 0.157)	0.009 (−0.149, 0.167)	0.092 (0.011, 0.173)	0.081 (0.008, 0.155)	0.041 (−0.010, 0.092)
Protein S	0.027	0.912	0.026	0.031	0.111
Factor VIII	0.088 (−0.001, 0.178)	−0.032 (− 0.225, 0.162)	0.095 (− 0.005, 0.196)	0.095 (0.006, 0.185)	0.042 (− 0.021, 0.104)
Factor VIII	0.053	0.749	0.061	0.037	0.192

Participants with anticoagulative medication were excluded from the linear regression analyses
Independent variables: lipid parameters (continuously). Adjusted for age, BMI, education (≤/> 10 years), diabetes, smoking (yes/no/never), systolic blood pressure, and intake of antihypertensive medication
aPTT activated partial prothrombin time

ISSN: 1476-511X