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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Supplementation with sesame oil suppresses genotoxicity, hepatotoxicity and enterotoxicity induced by sodium arsenite in rats

Fig. 3

Representative photomicrographs of sections of the liver and colon in rats treated with SA and SSO. A H&E-stained histopathological features (100×) of rat livers. Liver tissues of SA-treated rats (Group B) showed necrosis, degeneration of hepatocytes and appearance of apoptotic bodies (blue arrow), congestion of central vein (red arrow) and sinusoids (black arrows). Group C (SA + SSO) showed a lower degree of degeneration of liver tissue, with inflammatory cell infiltration (green arrow), although congestion of the central vein did not show any improvement. Sections from Group A (control) and Group D (SSO only) were well preserved and showed no abnormalities. B H&E-stained histopathological features (400×) of the rat colon. The colon tissues from Groups A and D showed normal architecture with normal morphology of the epithelium, mucosal and submucosal glands. Group B (SA-treated) showed distortion of the epithelium, with possible erosions (black arrow) and inflammatory cell infiltration (green arrows). Group C (SA + SSO) showed well-preserved epithelium, but a few inflammatory cells were still observed (green arrows)

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Lipids in Health and Disease

ISSN: 1476-511X