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Table 1 Clinical and biochemical characteristics

From: Sex difference in the relationship of the Atherogenic index of plasma with coronary artery lesions in diabetes: a cross-sectional study

 

Total(n = 737)

Male(n = 412)

Female(n = 325)

 

Control(n = 201)

CAD(n = 536)

P1

Control(n = 92)

CAD(n = 320)

P2

Control(n = 109)

CAD(n = 216)

P3

P4

Smoking,n%

52(25.9)

224(41.8)

<0.001

49(53.3)

223(69.7)

0.003

3(2.8)

1(0.5)

0.217

<0.001

Hypertension,n%

132(65.7)

376(70.1)

0.242

58(63.0)

209(65.3)

0.688

74(67.9)

167(77.3)

0.067

<0.001

Age, years

60(10)

62(10)

0.072

58(10)

60(10)

0.201

63(10)

66(9)

0.005

<0.001

BMI,kg/m2

25.9(4.0)

25.4(4.1)

0.282

26.0(3.6)

26.0(3.6)

0.442

25.7(4.4)

24.8(3.8)

0.002

<0.001

DBP,mmHg

79(11)

78(11)

0.349

81(13)

79(11)

0.158

77(9)

77(11)

0.682

0.004

SBP,mmHg

132(18)

135(19)

0.046

131(17)

133(18)

0.570

133(18)

140(19)

0.004

<0.001

LDL-C,mmol/L

2.11(0.76)

2.13(0.83)

0.764

2.00(0.73)

2.09(0.82)

0.290

2.21(0.78)

2.19(0.84)

0.821

0.031

TG,mmol/L

1.34(0.92)

1.53(0.96)

<0.001

1.12(0.80)

1.55(0.97)

<0.001

1.47(0.94)

1.49(1.02)

0.466

0.553

HDL-C,mmol/L

1.00(0.33)

0.87(0.25)

<0.001

0.93(0.29)

0.82(0.21)

<0.001

1.04(0.32)

0.98(0.32)

0.027

<0.001

TC,mmol/L

3.71(0.88)

3.71(0.97)

0.968

3.49(0.85)

3.60(0.97)

0.342

3.89(0.87)

3.86(0.97)

0.807

<0.001

aAIP

1.12(0.25)

1.26(0.25)

<0.001

1.09(0.24)

1.31(0.23)

<0.001

1.14(0.26)

1.18(0.27)

0.170

<0.001

AST,U/L

19(10)

20(10)

0.035

21(12)

20(9)

0.817

18(8)

20(10)

0.024

0.014

HbA1c,%

7.1(1.2)

7.5(1.5)

<0.001

7.1(1.4)

7.6(1.5)

0.005

7.0(1.1)

7.4(1.5)

0.007

0.049

ALB,g/L

40.8(4.2)

39.9(3.5)

0.004

41.3(4.6)

40.0(3.5)

0.012

40.4(3.7)

39.8(3.6)

0.170

0.191

D-dimer, mg/L

0.40(0.30)

0.48(0.30)

0.039

0.32(0.20)

0.40(0.30)

0.003

0.50(0.35)

0.50(0.30)

0.317

<0.001

FIB,g/L

2.96(0.92)

3.19(0.99)

<0.001

2.64(0.84)

3.13(1.01)

<0.001

3.17(0.80)

3.27(1.00)

0.004

<0.001

FDP,mg/L

1.10(0.60)

1.24(0.67)

0.001

1.00(0.69)

1.20(0.66)

0.001

1.20(0.78)

1.36(0.80)

0.012

<0.001

eGFR,ml/min/1.73m2

100.64(14.00)

98.35(13.75)

0.045

103.94(13.32)

100.36(13.78)

0.027

97.86(14.02)

95.38(13.18)

0.118

<0.001

Hb,g/L

140(15)

137(17)

0.034

150(12)

144(15)

<0.001

131(13)

127(13)

0.006

<0.001

WBC, 109/L

6.24(2.2)

6.46(2.36)

0.059

6.26(2.13)

6.64(2.53)

0.036

6.24(2.30)

6.28(2.40)

0.956

0.003

Monocyte, 109/L

0.33(0.14)

0.34(0.16)

0.001

0.34(0.13)

0.36(0.16)

0.002

0.32(0.15)

0.31(0.14)

0.417

<0.001

Lymphocyte, 109/L

1.72(0.73)

1.61(0.71)

0.160

1.62(0.68)

1.60(0.70)

0.586

1.80(0.86)

1.63(0.73)

0.242

0.092

Neutrophils, 109/L

3.97(1.74)

4.28(1.90)

0.011

3.96(1.68)

4.51(1.93)

0.013

3.99(1.79)

4.08(1.80)

0.633

<0.001

Antidiabetic,n%

106(52.7)

314(58.6)

0.153

44(47.8)

181(56.7)

0.138

62(56.9)

133(61.6)

0.415

0.142

Insulin,n%

37(18.4)

113(21.1)

0.422

23(25.0)

67(20.9)

0.406

14(12.8)

46(21.3)

0.064

0.257

  1. P1 = reflect baseline characteristics between patients with and without CAD in all participants; P2 = reflect baseline characteristics between patients with and without CAD in males; P3 = reflect baseline characteristics between patients with and without CAD in females; P4 = reflect baseline characteristics between males and females
  2. CAD coronary artery disease, BMI body mass index, DBP diastolic blood pressure, SBP systolic blood pressure, aAIP adjusted atherogenic index of plasma, ALB albumin, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, FIB fibrinogen, FDP fibrinogen degradation products apolipoprotein, HbA1c glycosylated hemoglobin, AST aspartate aminotransferase, Hb hemoglobin, TG triglyceride, TC total cholesterol, WBC white blood cell, eGFR evaluation of glomerular filtration rate