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Table 3 Relationship between GGT/HDL-C and incident of DM2 in different models

From: The relationship between the ratio of gamma-glutamyltransferase to high-density lipoprotein cholesterol and the risk of diabetes mellitus using publicly available data: a secondary analysis based on a longitudinal study in Japan

Exposure

Crude model (HR, 95% CI, P)

Model I (HR, 95% CI, P)

Model II (HR, 95% CI, P)

GGT/HDL-C

1.015 (1.013, 1.017) < 0.00001

1.010 (1.007, 1.014) < 0.00001

1.005 (1.000, 1.010) 0.0670

GGT/HDL-C quartiles

 Q1

Ref

Ref

Ref

 Q2

2.22 (1.30, 3.78) 0.0033

1.87 (1.09, 3.22) 0.0228

1.28 (0.74, 2.20) 0.3790

 Q3

4.04 (2.47, 6.62) < 0.0001

2.75 (1.62, 4.68) 0.0002

1.25 (0.73, 2.16) 0.4171

 Q4

11.59 (7.34, 18.30) < 0.0001

6.08 (3.59, 10.29) < 0.0001

1.84 (1.04, 3.24) 0.0361

P for trend

 < 0.0001

 < 0.0001

0.00396

  1. Crude model did not adjust for other covariants
  2. Model I adjusted for age, sex, BMI
  3. Model II adjusted for age, sex, BMI, SBP, DBP, ALT, AST, TC, TG, HbA1C, FPG, fatty liver, smoking and exercise status and ethanol consumption
  4. CI Confidence interval, Ref Reference
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Lipids in Health and Disease

ISSN: 1476-511X