Skip to main content

Table 5 Effect size of GGT/HDL-C on incident DM2 in prespecified and exploratory subgroups

From: The relationship between the ratio of gamma-glutamyltransferase to high-density lipoprotein cholesterol and the risk of diabetes mellitus using publicly available data: a secondary analysis based on a longitudinal study in Japan

Character

Number of participant

Effect size (95%CI)

P value

P for interaction

Age (years)

   

0.7182

  < 60

14,741

1.00 (1.00, 1.01)

0.0903

 

  >  = 60

712

1.00 (0.98, 1.02)

0.9106

 

Sex

   

0.9279

 Male

8419

1.005 (0.983, 1.027)

0.6853

 

 Female

7034

1.006 (1.000, 1.011)

0.0455*

 

BMI (kg/m2)

   

0.6066

  < 23

10,059

1.004 (0.996, 1.012)

0.3575

 

  >  = 23

5394

1.006 (1.000, 1.012)

0.0375*

 

SBP (mmHg)

   

0.4241

  < 140

14,668

1.00 (1.00, 1.01)

0.1285

 

  >  = 140

785

1.01 (1.00, 1.03)

0.1511

 

DBP (mmHg)

   

0.3525

  < 90

14,690

1.00 (1.00, 1.01)

0.1642

 

  >  = 90

763

1.01 (1.00, 1.02)

0.0866

 

Current smoker

   

0.7553

 Never

9027

1.00 (0.99, 1.02)

0.3915

 

 Past

2949

1.01 (1.00, 1.02)

0.1355

 

 Current

3477

1.00 (0.99, 1.01)

0.4486

 

Drinking status

   

0.5413

 Non

11,802

1.00 (1.00, 1.01)

0.2545

 

 Light

1754

1.00 (0.99, 1.02)

0.5992

 

 Moderate

1357

1.00 (0.98, 1.01)

0.6772

 

 Heavy

540

1.02 (1.00, 1.03)

0.0150*

 

Fatty liver

   

0.4586

 No

12,716

1.00 (1.00, 1.01)

0.4310

 

 Yes

2737

1.007 (1.001, 1.014)

0.0290*

 

Exercise

   

0.3589

 No

12,747

1.004 (0.998, 1.010)

0.1552

 

 Yes

2706

1.012 (0.997, 1.027)

0.1164

 
  1. Note 1: Above model adjusted for age, sex, BMI, SBP, DBP, FPG, ALT, AST, HBA1C, TC, TG, fatty liver, smoking and drinking status, exercise status
  2. Note 2: In each case, the model is not adjusted for the stratification variable