Lipids in Health and Disease

Table 3 Pharmacokinetic properties of the selected molecules capsaicin, rosamarinic acid and resveratrol

From: In silico profiling of nonsynonymous SNPs of fat mass and obesity-associated gene: possible impacts on the treatment of non-alcoholic fatty liver disease

Molecules	GI absorption	BBB permeant	Pgp substrate	CYP1A2 inhibitor	CYP2C19 inhibitor	CYP2C9 inhibitor	CYP2D6 inhibitor	CYP3A4 inhibitor	log Kp (cm/s)
Capsaicin	High	Yes	No	Yes	No	No	Yes	Yes	-5.62
Rosamarinic acid	Low	No	No	No	No	No	No	No	-6.82
Resveratrol	High	Yes	No	Yes	No	Yes	No	Yes	-5.47

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ISSN: 1476-511X

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