Table 2 Univariate and multivariate COX analysis of OS in RCC patients after nephrectomy

Gender (male vs female)

2.158 (1.075–4.331)

0.031^*

Age

1.041 (1.012–1.072)

0.006^**

1.053 (1.020–1.087)

0.001^**

BMI

0.950 (0.886–1.044)

0.288

Smoking history (no vs yes)

0.297 (0.168–0.524)

< 0.001^**

0.287 (0.153–0.535)

< 0.001^**

Hypertension (no vs yes)

1.010 (0.566–1.801)

0.974

Laterality (left vs right)

1.140 (0.647–2.008)

0.650

Tumor size

1.393 (1.284–1.511)

< 0.001^**

1.515 (1.289–1.782)

< 0.001^**

Tumor subtype

(non-clear vs clear)

2.959 (1.432–6.112)

0.003^**

4.215 (1.894–9.377)

< 0.001^**

T stage

< 0.001^**

0.316

T1

Reference

Reference

T2

5.093 (2.628–9.870)

< 0.001^**

0.455 (0.152–1.363)

0.159

T3-T4

6.815 (2.974–15.616)

< 0.001^**

0.463 (0.146–1.471)

0.192

N stage (N0/Nx vs N+)

0.113 (0.035–0.365)

< 0.001^**

0.104 (0.028–0.379)

0.001^**

Fuhrman grade

< 0.001^**

0.011^*

1

Reference

Reference

2

1.716 (0.582–5.066)

0.328

1.137 (0.372–3.477)

0.821

3

5.827 (1.967–17.258)

0.001^**

2.370 (0.774–7.259)

0.131

4

13.433 (3.757–48.021)

< 0.001^**

5.321 (1.407–20.127)

0.014^*

Type of surgery (PN vs RN)

0.901 (0.299–2.720)

0.853

LDL-C (≤ 1.93 vs > 1.93)

2.740 (1.469–5.110)

0.002^**

2.337 (1.192–4.581)

0.013^*