Table 3 Univariate and multivariate COX analysis of CSS in RCC patients after nephrectomy

Gender (male vs female)

1.382 (0.636–3.002)

0.414

Age

1.042 (1.005–1.080)

0.025^*

BMI

0.937 (0.833–1.055)

0.284

Smoking history (no vs yes)

0.427 (0.210–0.867)

0.019^*

Hypertension (no vs yes)

1.212 (0.581–2.530)

0.609

Laterality (left vs right)

0.935 (0.461–1.898)

0.853

Tumor size

1.391 (1.259–1.538)

< 0.001^**

1.345 (1.133–1.597)

0.001^**

Tumor subtype

(non-clear vs clear)

3.719 (1.601–8.637)

0.002^**

3.199 (1.252–8.171)

0.015^*

T stage

< 0.001^*

0.725

T1

Reference

Reference

T2

4.689 (2.033–10.813)

< 0.001^**

0.578 (0.151–2.217)

0.424

T3-T4

7.450 (2.763–20.089)

< 0.001^**

0.690 (0.153–3.102)

0.628

N stage (N0/Nx vs N+)

0.116 (0.028–0.488)

0.003^**

0.204 (0.044–0.957)

0.044^*

Fuhrman grade

< 0.001^**

0.051

1

Reference

Reference

2

4.855 (0.636–37.031)

0.128

3.415 (0.440–26.522)

0.240

3

13.886 (1.795–107.395)

0.012^*

6.677 (0.833–53.492)

0.074

4

33.375 (3.705–300.621)

0.002^**

13.476 (1.434–126.634)

0.023^*

Type of surgery (PN vs RN)

0.344 (0.065–1.822)

0.210

LDL-C (≤ 1.93 vs > 1.93)

3.197 (1.504–6.794)

0.003^**

3.347 (1.515–7.392)

0.003^**