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Table 2 Association of CAD with serum GDF-15 in HUA men

From: Serum growth differentiation factor-15 and non-esterified fatty acid levels in patients with coronary artery disease and hyperuricemia

GDF-15

n

Conc range,

OR(95%CI)

quartile

 

pg/dL

Crude

Model 1

Model 2

Quartile 1

89

 ≤ 5.00

Reference

Reference

Reference

(low)

Quartile 2

86

5.01–7.06

2.337

2.331

2.269

   

(1.187, 4.601)

(1.178, 4.616)

(0.948, 5.433)

Quartile 3

88

7.07–9.80

4.320

4.182

4.128

   

(2.221, 8402)

(2.130, 8.207)

(1.750, 9.734)

Quartile 4

87

 ≥ 9.81

10.354

10.455

10.476

(high)

  

(5.147, 20.829)

(5.100, 21.433)

(4.158, 26.391)

β

  

0.759

0.758

0.764

SE

  

0.110

0.113

0.148

P for trend

  

 < 0.001

 < 0.001

 < 0.001

  1. Serum GDF-15 was divided into quartiles (quartile 1: < 25th, quartile 2: 25–50th, quartile 3: 50–75th, quartile 4: > 75th percentile)
  2. Crude: No adjustment
  3. Model 1: Adjusted for age, smoking, alcohol consumption, Diabetes Mellitus, Hypertension, SBP, DBP
  4. Model 2: Adjusted for the same variables as Model 1 as well as Urea, Cr, UA,FPG, TC, TG, HDL-c and LDL-c
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Lipids in Health and Disease

ISSN: 1476-511X