Skip to main content
Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Exercise activates Sirt1-mediated Drp1 acetylation and inhibits hepatocyte apoptosis to improve nonalcoholic fatty liver disease

Fig. 4

Sirt1 inhibitors reverse aerobic exercise-reduced Drp1 acetylation and mitochondrial dysfunction. A Western blot for detecting the acetylation level of total protein; B Western blot for the acetylation level of Drp1; C Western blot for the acetylation levels of Drp1 in cytoplasm and mitochondria; D-F: Kit for the contents of SOD, GSH and MDA; G Western blot for the protein level of Sirt1, Mfn2, Drp1 and Opa1; H Blood lipid detection of rat; I ALT and AST content of rat serum; J HE and oil red O dying of rat liver tissue. (T6, tenovin-6). (*P < 0.05, **P < 0.01, *** P < 0.001; ns: no significant difference)

Back to article page

Lipids in Health and Disease

ISSN: 1476-511X