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Fig. 8 | Lipids in Health and Disease

Fig. 8

From: Exercise activates Sirt1-mediated Drp1 acetylation and inhibits hepatocyte apoptosis to improve nonalcoholic fatty liver disease

Fig. 8

Sirt1 attenuates OA-induced lipid accumulation and mitochondrial dysfunction in HepG2 cells by regulating Drp1 acetylation. A Western blot for Drp1 acetylation; B Western blot for Drp1 protein expression; C Oil red O staining for lipid accumulation; D Immunofluorescence for ROS content; E–H Kit for ATP, mtDNA, OXPHOS and ΔΨm levels; I Western blot for NRF1 and TFAM protein levels; immunofluorescence for NRF1 and TFAM levels. (*P < 0.05, **P < 0.01, *** P < 0.001; ns: no significant difference)

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Lipids in Health and Disease

ISSN: 1476-511X