Control | IFG | IGT | IFG + IGT | T2D | ||
---|---|---|---|---|---|---|
Nf | 196 | 167 | 21 | 29 | 19 | |
Nnf | 251 | 193 | 26 | 68 | 57 | |
Lipoprotein | Fasting state | c [nM] | c [nM] | c [nM] | c [nM] | c [nM] |
HDL A | Fasting | 16,628 ± 2839 | 16,885 ± 2939 | 16,725 ± 2658 | 17,107 ± 2445 | 17,408 ± 2776 |
(7 – 8.5 nm) | Non-fasting | 16,963 ± 3320 | 17,362 ± 2777 | 16,799 ± 2420 | 17,285 ± 2251 | 18,014 ± 2454 |
Δcnf-f [%] | 2 | 2.8 | 0.4 | 1 | 3.5 | |
HDL B | Fasting | 4688 ± 1451 | 4247 ± 1331 | 4586 ± 1692 | 4724 ± 1530 | 4218 ± 1123 |
(8.5 – 10 nm) | Non-fasting | 4623 ± 1442 | 4501 ± 1267 | 4479 ± 1778 | 4779 ± 1493 | 4390 ± 1156 |
Δcnf-f [%] | -1.4 | 6 | -2.3 | 1.2 | 4.1 | |
HDL C | Fasting | 2445 ± 903 | 2106 ± 695 | 2309 ± 1086 | 2259 ± 612 | 2004 ± 593 |
(10 – 13 nm) | Non-fasting | 2407 ± 827 | 2270 ± 749 | 2300 ± 1049 | 2263 ± 614 | 2085 ± 565 |
Δcnf-f [%] | -1.6 | 7.8 | -0.4 | 0.2 | 4.1 | |
HDL D | Fasting | 1159 ± 206 | 1111 ± 170 | 1184 ± 228 | 1174 ± 183 | 1125 ± 147 |
(13 – 16 nm) | Non-fasting | 1154 ± 193 | 1158 ± 176 | 1193 ± 235 | 1170 ± 155 | 1149 ± 162 |
Δcnf-f [%] | -0.5 | 4.2 | 0.7 | -0.3 | 2.1 | |
HDL total | Fasting | 24,921 ± 3488 | 24,349 ± 3423 | 24,805 ± 3272 | 25,265 ± 2840 | 24,754 ± 3003 |
(7 – 16 nm) | Non-fasting | 25,147 ± 3874 | 25,290 ± 3234 | 24,771 ± 3104 | 25,498 ± 2947 | 25,638 ± 3128 |
Δcnf-f [%] | 0.9 | 3.9 | -0.1 | 0.9 | 3.6 | |
Apo-A1NMRb | Fasting | 49,842 ± 6976 | 48,698 ± 6845 | 49,611 ± 6543 | 50,529 ± 5679 | 49,508 ± 6006 |
Non-fasting | 50,294 ± 7749 | 50,581 ± 6468 | 49,543 ± 6207 | 50,996 ± 5893 | 51,276 ± 6255 | |
Δcnf-f [%] | 0.9 | 3.9 | -0.1 | 0.9 | 3.6 | |
LDL A | Fasting | 469.2 ± 127.2 | 426.4 ± 97.6 | 469.6 ± 172.6 | 455.1 ± 81.2 | 395.1 ± 97.6 |
(16 – 19 nm) | Non-fasting | 465.5 ± 118.5 | 449.9 ± 105.7 | 461.4 ± 174.8 | 452.0 ± 87.9 | 420.7 ± 86.3 |
Δcnf-f [%] | -0.8 | 5.5 | -1.7 | -0.7 | 6.5 | |
LDL B | Fasting | 370.0 ± 74.3 | 354.3 ± 61.0 | 375.2 ± 85.6 | 374.5 ± 59.8 | 339.1 ± 59.0 |
(19 – 21 nm) | Non-fasting | 369.4 ± 72.2 | 367.3 ± 66.0 | 374.2 ± 89.8 | 371.1 ± 57.4 | 358.8 ± 59.1 |
Δcnf-f [%] | -0.2 | 3.7 | -0.3 | -0.9 | 5.8 | |
LDL C | Fasting | 328.5 ± 66.5 | 314.9 ± 56.4 | 331.2 ± 78.5 | 328.6 ± 54.5 | 296.2 ± 63.4 |
(21 – 22 nm) | Non-fasting | 329.9 ± 70.1 | 323.0 ± 64.7 | 326.7 ± 82.9 | 324.6 ± 53.9 | 311.5 ± 55.9 |
Δcnf-f [%] | 0.4 | 2.6 | -1.4 | -1.2 | 5.1 | |
LDL D | Fasting | 221.3 ± 48.7 | 216.9 ± 45.1 | 225.0 ± 54.2 | 229.0 ± 51.1 | 205.1 ± 53.7 |
(22 – 25 nm) | Non-fasting | 223.6 ± 57.1 | 223.1 ± 47.1 | 227.5 ± 59.1 | 224.0 ± 47.1 | 219.2 ± 47.0 |
Δcnf-f [%] | 1 | 2.8 | 1.1 | -2.2 | 6.9 | |
LDL E | Fasting | 175.6 ± 41.9 | 180.3 ± 41.0 | 185.4 ± 35.7 | 196.6 ± 58.0 | 169.8 ± 44.1 |
(25 – 30 nm) | Non-fasting | 177.6 ± 53.2 | 183.2 ± 46.1 | 187.6 ± 38.2 | 191.5 ± 45.3 | 188.8 ± 47.8 |
Δcnf-f [%] | 1.1 | 1.6 | 1.2 | -2.6 | 11.2 | |
LDL total | Fasting | 1564.7 ± 328.1 | 1492.9 ± 273.4 | 1586.4 ± 406.0 | 1583.7 ± 266.8 | 1405.2 ± 286.3 |
(16 – 30 nm) | Non-fasting | 1566.0 ± 336.1 | 1546.5 ± 301.0 | 1577.2 ± 423.9 | 1563.1 ± 262.4 | 1498.8 ± 271.7 |
Δcnf-f [%] | 0.1 | 3.6 | -0.6 | -1.3 | 6.7 | |
IDL | Fasting | 83.41 ± 20.95 | 84.43 ± 20.27 | 83.41 ± 19.31 | 91.8 ± 28.37 | 78.71 ± 23.38 |
(30 – 40 nm) | Non-fasting | 84.87 ± 27.24 | 85.67 ± 21.48 | 86.58 ± 19.4 | 88.13 ± 21.97 | 86.57 ± 22.98 |
Δcnf-f [%] | 1.8 | 1.5 | 3.8 | -4 | 10 | |
VLDL A | Fasting | 42.93 ± 13.76 | 45.08 ± 13.79 | 45.22 ± 12.18 | 51.88 ± 23.09 | 43.17 ± 15.54 |
(40 – 60 nm) | Non-fasting | 43.33 ± 17.74 | 45.98 ± 14.42 | 48.03 ± 11.93 | 49.4 ± 15.7 | 48.95 ± 16.87 |
Δcnf-f [%] | 0.9 | 2 | 6.2 | -4.8 | 13.4 | |
VLDL B | Fasting | 9.92 ± 3.22 | 10.32 ± 3.26 | 10.1 ± 3.03 | 12.28 ± 6.02 | 9.35 ± 3.23 |
(60 – 80 nm) | Non-fasting | 10.06 ± 4.34 | 10.5 ± 3.42 | 10.74 ± 2.68 | 11.35 ± 3.61 | 11.19 ± 4.11 |
Δcnf-f [%] | 1.4 | 1.7 | 6.3 | -7.6 | 19.7 | |
IDL and VLDL | Fasting | 136.26 ± 37.08 | 139.83 ± 36.48 | 138.72 ± 33.32 | 155.95 ± 56.55 | 131.22 ± 40.77 |
(30 – 80 nm) | Non-fasting | 138.27 ± 48.51 | 142.15 ± 38.65 | 145.35 ± 32.75 | 148.88 ± 40.54 | 146.71 ± 43.34 |
Δcnf-f [%] | 1.5 | 1.7 | 4.8 | -4.5 | 11.8 | |
Apo-B100NMRb | Fasting | 1700.9 ± 352.0 | 1632.7 ± 300.9 | 1725.1 ± 431.3 | 1739.6 ± 310.7 | 1536.4 ± 318.3 |
Non-fasting | 1704.2 ± 372.0 | 1688.6 ± 329.4 | 1722.6 ± 449.1 | 1712.0 ± 294.3 | 1645.5 ± 306.3 | |
Δcnf-f [%] | 0.2 | 3.4 | -0.1 | -1.6 | 7.1 | |
CM Re | Fasting | 0.66 ± 0.28 | 0.7 ± 0.28 | 0.7 ± 0.25 | 0.86 ± 0.52 | 0.68 ± 0.33 |
(80 – 100 nm) | Non-fasting | 0.66 ± 0.35 | 0.73 ± 0.28 | 0.77 ± 0.23 | 0.8 ± 0.33 | 0.78 ± 0.34 |
Δcnf-f [%] | 0 | 4.3 | 10 | -7 | 14.7 | |
CM A | Fasting | 0.42 ± 0.17 | 0.44 ± 0.18 | 0.43 ± 0.16 | 0.56 ± 0.35 | 0.4 ± 0.17 |
(100 – 150 nm) | Non-fasting | 0.42 ± 0.23 | 0.45 ± 0.18 | 0.47 ± 0.14 | 0.51 ± 0.2 | 0.5 ± 0.23 |
Δcnf-f [%] | 0 | 2.3 | 9.3 | -8.9 | 25 | |
CM B | Fasting | 0.075 ± 0.039 | 0.079 ± 0.04 | 0.076 ± 0.041 | 0.109 ± 0.083 | 0.066 ± 0.041 |
(> 150 nm) | Non-fasting | 0.073 ± 0.051 | 0.082 ± 0.038 | 0.0810 ± 0.030 | 0.095 ± 0.046 | 0.088 ± 0.048 |
Δcnf-f [%] | -2.7 | 3.8 | 6.6 | -12.8 | 33.3 | |
CM total | Fasting | 1.15 ± 0.48 | 1.22 ± 0.49 | 1.21 ± 0.45 | 1.53 ± 0.94 | 1.14 ± 0.54 |
(80 – 430 nm) | Non-fasting | 1.15 ± 0.62 | 1.26 ± 0.49 | 1.32 ± 0.38 | 1.41 ± 0.57 | 1.37 ± 0.61 |
Δcnf-f [%] | 0 | 3.3 | 9.1 | -7.8 | 20.2 | |
Apo-B48NMRb | Fasting | 1.15 ± 0.48 | 1.22 ± 0.49 | 1.21 ± 0.45 | 1.53 ± 0.94 | 1.14 ± 0.54 |
Non-fasting | 1.15 ± 0.62 | 1.26 ± 0.49 | 1.32 ± 0.38 | 1.41 ± 0.57 | 1.37 ± 0.61 | |
Δcnf-f [%] | 0 | 3.3 | 9.1 | -7.8 | 20.2 |