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  1. Content type: Research

    Cholesterol ester storage disease (CESD) is an autosomal recessive illness that results from mutations in the LIPA gene encoding lysosomal acid lipase. CESD patients present in childhood with hepatomegaly and dys...

    Authors: Venu T Tadiboyina, Dora M Liu, Brooke A Miskie, Jian Wang and Robert A Hegele

    Citation: Lipids in Health and Disease 2005 4:26

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  2. Content type: Research

    Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. Some in vitro experiments have previously suggested that high-density lipoprotein (HDL) co-incu...

    Authors: T Solakivi, O Jaakkola, A Salomäki, N Peltonen, S Metso, T Lehtimäki, H Jokela and ST Nikkari

    Citation: Lipids in Health and Disease 2005 4:25

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  3. Content type: Research

    Postprandial lipemia is an independent risk factor for coronary heart disease. Single bouts of moderate exercise may lower this risk, but the minimum duration of moderate intensity exercise that still lowers p...

    Authors: Martina Pfeiffer, Tanja Ludwig, Caspar Wenk and Paolo C Colombani

    Citation: Lipids in Health and Disease 2005 4:24

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  4. Content type: Research

    In man, elevated levels of plasma lipoprotein (a)(Lp(a)) is a cardiovascular risk factor, and oxidized phospholipids are believed to play a role as modulators of inflammatory processes such as atherosclerosis....

    Authors: Knut A Eliassen, Bjørn P Brodal, Aud Svindland, Harald Osmundsen, Helle Rønning, Srdjan Djurovic and Kåre Berg

    Citation: Lipids in Health and Disease 2005 4:23

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  5. Content type: Research

    In the present study, the effects of subchronic treatments (4 weeks) of hypercholesterolemic (single) and diabetic-hypercholesterolemic (combined) rats with 4 (3H) quinazolinone and 2 halogenated derivatives (...

    Authors: Fawzia M Refaie, Amr Y Esmat, Soad M Abdel Gawad, Aida M Ibrahim and Mona A Mohamed

    Citation: Lipids in Health and Disease 2005 4:22

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  6. Content type: Research

    The metabolic syndrome (MetS), as well as postprandial hypertriglyceridemia, is associated with coronary heart disease. This study aimed to evaluate the postprandial lipemia after oral fat tolerance test (OFTT...

    Authors: Genovefa D Kolovou, Katherine K Anagnostopoulou, Antonis N Pavlidis, Klelia D Salpea, Stella A Iraklianou, Konstantinos Tsarpalis, Dimitris S Damaskos, Athanasios Manolis and Dennis V Cokkinos

    Citation: Lipids in Health and Disease 2005 4:21

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  7. Content type: Research

    Reference data for plasma lipids and blood pressure are not available for Asian Indian adolescents. This study aimed to develop representative age- and sex- specific percentile reference data for serum lipids ...

    Authors: Malini Madhavan, Ravindra M Pandey, Anoop Misra, Naval K Vikram, Vibha Dhingra, Kalpana Luthra and Jasjeet S Wasir

    Citation: Lipids in Health and Disease 2005 4:20

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  8. Content type: Research

    In order to investigate the effects of lead exposure on risk of cardiovascular disease during occupational exposure to this metal, plasma cholesterol and its fractions as high-density liporotein (HDL), low-den...

    Authors: Oladipo Ademuyiwa, Regina Ngozi Ugbaja, Florence Idumebor and Olugbenga Adebawo

    Citation: Lipids in Health and Disease 2005 4:19

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  9. Content type: Research

    Butyrylcholinesterase is an enzyme that may serve as a marker of metabolic syndrome. We (a) measured its level in persons with diabetes mellitus, (b) constructed a family tree of the enzyme using nucleotide se...

    Authors: GR Sridhar, G Nirmala, Allam Apparao, AS Madhavi, S Sreelatha, J Sudha Rani and P Vijayalakshmi

    Citation: Lipids in Health and Disease 2005 4:18

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  10. Content type: Research

    NPC1L1 encodes a putative intestinal sterol transporter which is the likely target for ezetimibe, a new type of lipid-lowering medication. We previously reported rare non-synonymous mutations in NPC1L1 in an indi...

    Authors: Robert A Hegele, Justin Guy, Matthew R Ban and Jian Wang

    Citation: Lipids in Health and Disease 2005 4:16

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  11. Content type: Research

    Abstract Hyperlipidemia and increased degree of oxidative stress are among the important risk factors for Atherosclerosis in renal transplant recipients (RTR). The Medical treatment of hyperlipidemia in RTR be...

    Authors: Abbas Jabbari, Hassan Argani, Amir Ghorbanihaghjo and Reza Mahdavi

    Citation: Lipids in Health and Disease 2005 4:11

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  12. Content type: Review

    The requirement of cholesterol for internalization of eukaryotic pathogens like protozoa (Leishmaniasis, Malaria and Toxoplasmosis) and the exchange of cholesterol along with other metabolites during reproduction...

    Authors: Devendra Bansal, Harinderpal Singh Bhatti and Rakesh Sehgal

    Citation: Lipids in Health and Disease 2005 4:10

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  13. Content type: Research

    Polyunsaturated fatty acids (PUFA) are thought to play important roles in inflammation. The n-3 series is considered as anti-inflammatory, and some studies have reported increased plasma n-3 polyunsaturated fa...

    Authors: Tiina Solakivi, Olli Jaakkola, Anne Kalela, Mari Pispa, Anne Salomäki, Terho Lehtimäki, Matti Höyhtyä, Hannu Jokela and Seppo T Nikkari

    Citation: Lipids in Health and Disease 2005 4:8

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  14. Content type: Review

    Metabolic syndrome is a collection of associated conditions such as dyslipidemia, high blood pressure, impaired glucose tolerance and tendency to develop fat around the abdomen. It is now well known that indiv...

    Authors: Demosthenes B Panagiotakos and Evangelos Polychronopoulos

    Citation: Lipids in Health and Disease 2005 4:7

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  15. Content type: Research

    This study tested the hypothesis that human macrophages have the ability to modify oxidation products in LDL and oxidized LDL (oxLDL) via a cellular antioxidant defence system. While many studies have focused ...

    Authors: Lillemor Mattsson Hultén, Christina Ullström, Alexandra Krettek, David van Reyk, Stefan L Marklund, Claes Dahlgren and Olov Wiklund

    Citation: Lipids in Health and Disease 2005 4:6

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  16. Content type: Research

    Autotaxin (ATX, NPP-2), originally purified as a potent tumor cell motility factor, is now known to be the long-sought plasma lysophospholipase D (LPLD). The integrity of the enzymatic active site, including t...

    Authors: Timothy Clair, Eunjin Koh, Malgorzata Ptaszynska, Russell W Bandle, Lance A Liotta, Elliott Schiffmann and Mary L Stracke

    Citation: Lipids in Health and Disease 2005 4:5

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  17. Content type: Research

    Protease inhibitors are known to alter the lipid profiles in subjects treated for HIV/AIDS. However, the magnitude of this effect on plasma lipoproteins and lipids has not been adequately quantified.

    Authors: Adrian R Levy, Lawrence McCandless, P Richard Harrigan, Robert S Hogg, Greg Bondy, Uchenna H Iloeje, Jayanti Mukherjee and Julio S Montaner

    Citation: Lipids in Health and Disease 2005 4:4

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  18. Content type: Research

    Studies in rodents and some studies in humans have shown that conjugated linoleic acid (CLA), especially its trans-10, cis-12 isomer, reduces body fat content. However, some but not all studies in mice and humans...

    Authors: Ed Wargent, Matthew V Sennitt, Claire Stocker, Andrew E Mayes, Louise Brown, Jacqueline O'Dowd, Steven Wang, Alexandra WC Einerhand, Inge Mohede, Jonathan RS Arch and Michael A Cawthorne

    Citation: Lipids in Health and Disease 2005 4:3

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  19. Content type: Research

    Transport of fatty acids within the cytosol of adipocytes and their subsequent assimilation into lipid droplets has been thoroughly investigated; however, the mechanism by which fatty acids are transported acr...

    Authors: Larissa C Wilsie, Shree Chanchani, Deepti Navaratna and Robert A Orlando

    Citation: Lipids in Health and Disease 2005 4:2

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  20. Content type: Research

    Apolipoprotein A-V (Apo A-V) gene has recently been identified as a new apolipoprotein involved in triglyceride metabolism. A single nucleotide polymorphism (SNP3) located in the gene promoter (-1131) was asso...

    Authors: Raja Chaaba, Nebil Attia, Sonia Hammami, Maha Smaoui, Sylvia Mahjoub, Mohamed Hammami and Ahmed Slaheddine Masmoudi

    Citation: Lipids in Health and Disease 2005 4:1

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  21. Content type: Research

    To determine the correlates of serum lipoprotein (a) (Lp(a)) in children and adolescents in the United States.

    Authors: Thomas O Obisesan, Muktar H Aliyu, Abayomi S Adediran, Vernon Bond, Celia J Maxwell and Charles N Rotimi

    Citation: Lipids in Health and Disease 2004 3:29

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  22. Content type: Research

    The lipoprotein lipase (LPL) hydrolyses circulating triacylglycerol-rich lipoproteins. Thereby, LPL acts as a metabolic gate-keeper for fatty acids partitioning between adipose tissue for storage and skeletal ...

    Authors: Florence Gondret, Sanjay B Jadhao, Marie Damon, Patrick Herpin, Céline Viglietta, Louis-Marie Houdebine and Jean-François Hocquette

    Citation: Lipids in Health and Disease 2004 3:27

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  23. Content type: Research

    The response of serum cholesterol to diet may be affected by the apolipoprotein E (APOE) ε2/ε3/ε4 polymorphism, which also is a significant predictor of variation in the risk of coronary heart disease (CHD) and C...

    Authors: Elisabeth Strandhagen, Henrik Zetterberg, Nibia Aires, Mona Palmér, Lars Rymo, Kaj Blennow and Dag S Thelle

    Citation: Lipids in Health and Disease 2004 3:26

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  24. Content type: Research

    Conjugated fatty acid, the general term of positional and geometric isomers of polyunsaturated fatty acids with conjugated double bonds, has attracted considerable attention because of its potentially benefici...

    Authors: Keisuke Arao, Yu-Ming Wang, Nao Inoue, Junichi Hirata, Jae-Young Cha, Koji Nagao and Teruyoshi Yanagita

    Citation: Lipids in Health and Disease 2004 3:24

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  25. Content type: Review

    Apolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-dens...

    Authors: Guanghua Luo, Xiaoying Zhang, Peter Nilsson-Ehle and Ning Xu

    Citation: Lipids in Health and Disease 2004 3:21

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  26. Content type: Research

    One of the primary causes of otitis media (OM), an inflammation of the middle ear, is the bacterium Haemophilus influenzae (HI). OM often occurs to young children, and is mostly treated with antibiotics. Due to c...

    Authors: Jim-Wen R Liu, Steve N Anderson, Jonathan A Meulbroek, Shie-Ming Hwang, Pradip Mukerji and Yung-Sheng Huang

    Citation: Lipids in Health and Disease 2004 3:20

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  27. Content type: Research

    Low levels of high density lipoprotein (HDL) cholesterol and disturbed postprandial lipemia are associated with coronary heart disease. In the present study, we evaluated the variation of triglyceride (TG) pos...

    Authors: Genovefa D Kolovou, Katherine K Anagnostopoulou, Nektarios Pilatis, Nikolaos Kafaltis, Konstandina Sorodila, Eleftherios Psarros and Dennis V Cokkinos

    Citation: Lipids in Health and Disease 2004 3:18

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  28. Content type: Research

    Restriction of fat intake has been effective in improving insulin sensitivity in obese and type 2 diabetic subjects, but what effects the recommended diet (less than 30% of total calories from fat) have not be...

    Authors: Chung-Jung Wu and Zer-Ran Yu

    Citation: Lipids in Health and Disease 2004 3:17

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  29. Content type: Research

    Malnutrition, anemia and increased atherosclerosis are the main causes of mortality in hemodialysis patients. Therapies designed to improve the disorders might therefore be expected to improve outcome. The eff...

    Authors: Amir Ghorbanihaghjo, Hassan Argani, Mohammad Rohbaninoubar and Nadereh Rashtchizadeh

    Citation: Lipids in Health and Disease 2004 3:16

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  30. Content type: Research

    Oxidative stress has been demonstrated in malaria. The potential oxidative modification of lipoproteins derived from malaria patients was studied. These oxidized lipids may have role in pathogenesis of malaria.

    Authors: Nathawut Sibmooh, Paveena Yamanont, Srivicha Krudsood, Wattana Leowattana, Gary Brittenham, Sornchai Looareesuwan and Rachanee Udomsangpetch

    Citation: Lipids in Health and Disease 2004 3:15

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  31. Content type: Research

    The theoretical benefits of using antioxidant vitamin supplements to quench oxygen free radicals appear large. High intensity aerobic-type exercise produces oxygen free radicals that can cause damage to lipid ...

    Authors: Peter E Viitala, Ian J Newhouse, Norm LaVoie and Christine Gottardo

    Citation: Lipids in Health and Disease 2004 3:14

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  32. Content type: Research

    The aim of the current study was to examine the influence of socioeconomic status (SES) on physiological (lipid profile, obesity indices) and behavioral (dietary habits, physical activity) cardiovascular disea...

    Authors: Yannis Manios, Maria Dimitriou, George Moschonis, Bike Kocaoglu, Haydar Sur, Yasar Keskin and Osman Hayran

    Citation: Lipids in Health and Disease 2004 3:11

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  33. Content type: Commentary

    The important role of APOAV gene T-1131>C variant in determination of plasma triglyceride levels has been proved on many population studies. Recently, associations between C-1131 allele and higher mother's height...

    Authors: Jaroslav A Hubacek, Zdena Skodova, Vera Adamkova, Vera Lanska, Dagmar Bobkova and Rudolf Poledne

    Citation: Lipids in Health and Disease 2004 3:10

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  34. Content type: Research

    The NCEP III -ATP guidelines provide clear clinical directives for lipid management especially statins therapy in appropriate patient groups. Compliance of primary care physicians with these guidelines especia...

    Authors: Zakari Y Aliyu, Sohair B Yousif, Kate Plantholt, Hamisu M Salihu, Ayodele Erinle and Steve Plantholt

    Citation: Lipids in Health and Disease 2004 3:9

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  35. Content type: Research

    The Lp(a) lipoprotein (Lp(a)) consists of the polymorphic glycoprotein apolipoprotein(a) (apo(a)), which is attached by a disulfide bond to apolipoprotein B (apoB). Apo(a), which has high homology with plasmin...

    Authors: Päivi A Teivainen, Knut A Eliassen, Edward M Rubin, Srdjan Djurovic and Kåre Berg

    Citation: Lipids in Health and Disease 2004 3:8

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  36. Content type: Short paper

    HMG-CoA reductase inhibitors (statins) are commonly used in medicine to control blood lipid disorder. Large clinical trials have demonstrated that statins greatly reduces cardiovascular-related morbidity and m...

    Authors: Martin Noël, Claude Gagné, Jean Bergeron, Jean Jobin and Paul Poirier

    Citation: Lipids in Health and Disease 2004 3:7

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  37. Content type: Research

    Atherosclerosis is the main cause of mortality and morbidity in end stage renal diseases (ESRD), especially in hemodialysis (HD) patients. In addition the classic risk factors for atherosclerosis, non classica...

    Authors: Hassan Argani, Amir Ghorbani, Nadereh Rashtchizade and Mohammad Rahbaninobar

    Citation: Lipids in Health and Disease 2004 3:6

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