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  1. This post hoc analysis assessed switching to ezetimibe/simvastatin 10/20 mg vs doubling the baseline statin dose to simvastatin 40 mg or atorvastatin 20 mg or switching to rosuvastatin 10 mg in subgroups of obese...

    Authors: Jeffrey B. Rosen, Jose G. Jimenez, Valdis Pirags, Hella Vides, Rachid Massaad, Mary E. Hanson, Philippe Brudi and Joseph Triscari
    Citation: Lipids in Health and Disease 2013 12:103
  2. The long-chain n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have human health benefits. Alternatives to fish as sources of EPA and DHA are needed. Oil from the micro-algae Nannochlor...

    Authors: Michael L. Kagan, Annette L. West, Christa Zante and Philip C. Calder
    Citation: Lipids in Health and Disease 2013 12:102
  3. Omega-3 PUFAs are known to have anti-inflammatory properties, and different mechanisms are involved. GPR120 is a G-protein coupled receptor that has recently received attention because of its anti-inflammatory...

    Authors: Kaia Mobraten, Trude M. Haug, Charlotte R. Kleiveland and Tor Lea
    Citation: Lipids in Health and Disease 2013 12:101
  4. The association of adverse health with high fat intake has long been recognized. However, the lack of research focusing on the interrelationship of thyroid and liver function, and the pathogenesis of a high fa...

    Authors: Venus Welch-White, Norma Dawkins, Thomas Graham and Ralphenia Pace
    Citation: Lipids in Health and Disease 2013 12:100
  5. There is considerable interest in dairy products from low-input systems, such as mountain-pasture grazing cows, because these products are believed to be healthier than products from high-input conventional sy...

    Authors: Louise B. Werner, Lars I. Hellgren, Marianne Raff, Søren K. Jensen, Rikke A. Petersen, Tue Drachmann and Tine Tholstrup
    Citation: Lipids in Health and Disease 2013 12:99
  6. Diabetes mellitus is a metabolic disease with multiple complications that causes serious diseases over the years. The condition leads to severe economic consequences and is reaching pandemic level globally. Mu...

    Authors: Sehamuddin Galadari, Anees Rahman, Siraj Pallichankandy, Alaa Galadari and Faisal Thayyullathil
    Citation: Lipids in Health and Disease 2013 12:98
  7. The association of genetic polymorphisms of Tanis with triglyceride concentration in human has not been thoroughly examined. We aimed to investigate the relationship between triglyceride concentrations and Tan...

    Authors: Ying Gao, Xiang Xie, Yi-Tong Ma, Yi-Ning Yang, Xiao-Mei Li, Zhen-Yan Fu, Ying-Ying Zheng, Xiang Ma, Bang-Dang Chen, Fen Liu and Ying Huang
    Citation: Lipids in Health and Disease 2013 12:97
  8. Conjugated linoleic acids (CLA) in general, and in particular the trans- 10,cis- 12 (t 10,c 12-CLA) isomer are potent modulators of milk fat synthesis in dairy cows. Studies in rodents, such as mice, have reveale...

    Authors: Ronny Kramer, Simone Wolf, Tobias Petri, Dirk von Soosten, Sven Dänicke, Eva-Maria Weber, Ralf Zimmer, Juergen Rehage and Gerhard Jahreis
    Citation: Lipids in Health and Disease 2013 12:96
  9. Epidemiological studies have verified the protective role of fish lipids in cardiovascular diseases. However, the effects of fish lipids on health boost remain undefined. Large amounts of by-products, such as ...

    Authors: Caixia Wang, Wenshui Xia, Yanshun Xu, Qixing Jiang, Shanshan Yin, Yuwei Yang and Peipie Yu
    Citation: Lipids in Health and Disease 2013 12:94
  10. To evaluate whether abnormal endothelial function, a common finding in gestational diabetes mellitus (GDM) pregnancies, can be explained by inflammatory cytokines.

    Authors: Ines Mrizak, Amel Arfa, Mariem Fekih, Haythem Debbabi, Ali Bouslema, Imen Boumaiza, Monia Zaouali, Naim A Khan and Zouhair Tabka
    Citation: Lipids in Health and Disease 2013 12:93
  11. Previous data suggested that intake of sodas and other acid beverages might be associated with increased levels of serum triglycerides, lowered HDL cholesterol, and increased formation of mono unsaturated fatt...

    Authors: Arne Torbjørn Høstmark, Marianne Sylvana Haug Lunde and Anna Haug
    Citation: Lipids in Health and Disease 2013 12:92
  12. We evaluated the cholesterol lowering efficacy of low-fat spoonable yoghurt with 1.9 g/d plant stanols as esters on plasma lipid profiles of Turkish subjects with mild to moderate hypercholesterolemia.

    Authors: Zehra Buyuktuncer, Mehmet Fisunoğlu, Gulay Sain Guven, Serhat Unal and Halit Tanju Besler
    Citation: Lipids in Health and Disease 2013 12:91
  13. Carissa opaca leaves are traditionally used in the treatment of male dysfunction and hormonal disorder as well as in oxidative stress in Pakistan and Asia. The present study was designed to assess the protective ...

    Authors: Sumaira Sahreen, Muhammad Rashid Khan, Rahmat Ali Khan and Naseer Ali Shah
    Citation: Lipids in Health and Disease 2013 12:90
  14. The fatty acid mixture of human milk is ideal for the newborn but little is known about its composition in the first few weeks of lactation. Of special interest are the levels of long-chain PUFAs (LCPUFAs), si...

    Authors: Gisela Adrienne Weiss, Heinz Troxler, Glynis Klinke, Daniela Rogler, Christian Braegger and Martin Hersberger
    Citation: Lipids in Health and Disease 2013 12:89
  15. The absorption of dietary long chain fatty acids (LCFA) largely occurs in the jejunum. LCFA are activated via conjugation with Coenzyme A (CoA), a reaction catalyzed by Acyl-CoA synthetases (ACS). Acyl-CoA syt...

    Authors: Nahum Meller, Michelle E Morgan, Winifred PS Wong, Jessica B Altemus and Ephraim Sehayek
    Citation: Lipids in Health and Disease 2013 12:88
  16. We have previously demonstrated that increased rates of superoxide generation by extra-mitochondrial enzymes induce the activation of the mitochondrial ATP-sensitive potassium channel (mitoKATP) in the livers of ...

    Authors: Luciane C Alberici, Bruno A Paim, Karina G Zecchin, Sandra R Mirandola, Cezar R Pestana, Roger F Castilho, Anibal E Vercesi and Helena CF Oliveira
    Citation: Lipids in Health and Disease 2013 12:87
  17. Nigella sativa belonging to the Ranunculaceae family has been reported to use for thousands of years as protective and curative traditional medicine against a number of diseases. GC-MS analysis of methanolic extr...

    Authors: Shafeeque Ahmad and Zafarul H Beg
    Citation: Lipids in Health and Disease 2013 12:86
  18. Hyperlipidaemia is a major risk factor for coronary artery disease (CAD) and cholesteryl ester transfer protein (CETP) gene polymorphisms are known to be associated with lipid profiles.

    Authors: Yongjian Lu, Naeimeh Tayebi, Hongzhe Li, Nilmani Saha, Hongyuan Yang and Chew-Kiat Heng
    Citation: Lipids in Health and Disease 2013 12:85
  19. Fatty acid synthase (FASN) is frequently activated and overexpressed in human cancers, and plays a crucial role in the carcinogenesis of various cancers. In this study, our aims were to explore the role of FAS...

    Authors: Nan Li, Heng Lu, Chunyan Chen, Xiaodong Bu and Peilin Huang
    Citation: Lipids in Health and Disease 2013 12:83
  20. Obesity is associated with abnormal fasting and postprandial lipids, which may link obesity with atherosclerosis. We explored fasting and postprandial lipids in morbidly obese patients treated with sleeve gast...

    Authors: Elisa Waldmann, Thomas P Hüttl, Burkhard Göke, Reinhold Lang and Klaus G Parhofer
    Citation: Lipids in Health and Disease 2013 12:82
  21. Inflammatory bowel diseases (IBD) are chronic intestinal inflammatory diseases affecting about 1% of western populations. New eating behaviors might contribute to the global emergence of IBD. Although the immu...

    Authors: Nabil Bosco, Viral Brahmbhatt, Manuel Oliveira, Francois-Pierre Martin, Pia Lichti, Frederic Raymond, Robert Mansourian, Sylviane Metairon, Cecil Pace-Asciak, Viktoria Bastic Schmid, Serge Rezzi, Dirk Haller and Jalil Benyacoub
    Citation: Lipids in Health and Disease 2013 12:81
  22. Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. We have previously shown that HDL does not protect LDL from oxidation in vitro, but is in fact ...

    Authors: Tiina Solakivi, Tarja Kunnas, Olli Jaakkola, Jaana Renko, Terho Lehtimäki and Seppo T Nikkari
    Citation: Lipids in Health and Disease 2013 12:80
  23. In recent years the physiological and pathological importance of fatty acids in both the periphery and central nervous system (CNS) has become increasingly apparent. However surprisingly limited research has b...

    Authors: Jade Guest, Manohar Garg, Ayse Bilgin and Ross Grant
    Citation: Lipids in Health and Disease 2013 12:79
  24. We have previously shown that treatment of Zucker rats and mice with diet-induced obesity with dietary docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids in the form of krill oil reduces peripheral levels ...

    Authors: Kjetil Berge, Fabiana Piscitelli, Nils Hoem, Cristoforo Silvestri, Ingo Meyer, Sebastiano Banni and Vincenzo Di Marzo
    Citation: Lipids in Health and Disease 2013 12:78
  25. Serum low-density lipoprotein cholesterol (LDL-C) is one of the most important risk factors for coronary heart disease. The aim of the present study was to investigate the relationship between LDL-C and body m...

    Authors: Takako Shirasawa, Hirotaka Ochiai, Tadahiro Ohtsu, Rimei Nishimura, Aya Morimoto, Hiromi Hoshino, Naoko Tajima and Akatsuki Kokaze
    Citation: Lipids in Health and Disease 2013 12:77
  26. The excessive accumulation of body fat is a major risk factor to develop a variety of metabolic diseases. To investigate the systematic association between the differences in gene expression profiling and adip...

    Authors: Chaowei Zhou, Jie Zhang, Jideng Ma, Anan Jiang, Guoqing Tang, Miaomiao Mai, Li Zhu, Lin Bai, Mingzhou Li and Xuewei Li
    Citation: Lipids in Health and Disease 2013 12:75
  27. Elevated total plasma homocysteine (tHcy) in humans is associated with cardiovascular disease but prevention trials have failed to confirm causality. Reported reasons for this association have been that homocy...

    Authors: Elisabet Söderström, Mats Eliasson, Owe Johnson, Göran Hallmans, Lars Weinehall, Jan-Håkan Jansson and Johan Hultdin
    Citation: Lipids in Health and Disease 2013 12:74
  28. Dietary polyunsaturated fatty acids (PUFA), especially eicosapentaenoic acid (EPA), improve lipid metabolism and contribute to the prevention of vascular diseases such as atherosclerosis. However, EPA in the d...

    Authors: Tharnath Nanthirudjanar, Hidehiro Furumoto, Takashi Hirata and Tatsuya Sugawara
    Citation: Lipids in Health and Disease 2013 12:73
  29. Previous studies have reported that different genotypes of PTPN11 gene (protein tyrosine phosphatase, non-receptor 11) were associated with different levels of serum lipids. The aim of this study was to explore t...

    Authors: Zhi-Fang Jia, Xue-Yuan Cao, Dong-Hui Cao, Fei Kong, Punyaram Kharbuja and Jing Jiang
    Citation: Lipids in Health and Disease 2013 12:72
  30. Polyunsaturated fatty acids (PUFAs) have tumoricidal action, though the exact mechanism of their action is not clear. The results of the present study showed that of all the fatty acids tested, linoleic acid (...

    Authors: Jinfeng Dai, Junhui Shen, Wensheng Pan, Shengrong Shen and Undurti N Das
    Citation: Lipids in Health and Disease 2013 12:71
  31. Variants of the secreted glycoprotein, proprotein convertase subtilisin/kexin 9 (PCSK9), associate with both hypo- and hyper-cholesterolemic phenotypes. Herein, we carried out full exonic sequencing of PCSK9 docu...

    Authors: Janice Mayne, Teik Chye Ooi, Angela Raymond, Marion Cousins, Lise Bernier, Thilina Dewpura, Francine Sirois, Majambu Mbikay, Jean Davignon and Michel Chrétien
    Citation: Lipids in Health and Disease 2013 12:70
  32. Chicken meat nutritional value with regard to fatty acid composition and selenium content depends on the choice of dietary oil and selenium level used in the chickens’ feed. The objective of this study was to ...

    Authors: Nicole F Nyquist, Rune Rødbotten, Magny Thomassen and Anna Haug
    Citation: Lipids in Health and Disease 2013 12:69
  33. Alzheimer’s disease (AD), the most common cause of dementia among neurodegenerative diseases, afflicts millions of elderly people worldwide. In addition to amyloid-beta (Aβ) peptide and phosphorylated tau, lip...

    Authors: Yoko Tajima, Masaki Ishikawa, Keiko Maekawa, Mayumi Murayama, Yuya Senoo, Tomoko Nishimaki-Mogami, Hiroki Nakanishi, Kazutaka Ikeda, Makoto Arita, Ryo Taguchi, Alato Okuno, Ryuta Mikawa, Shumpei Niida, Osamu Takikawa and Yoshiro Saito
    Citation: Lipids in Health and Disease 2013 12:68
  34. In a marker-trait association study we estimated the statistical significance of 65 single nucleotide polymorphisms (SNP) in 23 candidate genes on HDL levels of two independent Caucasian populations. Each popu...

    Authors: Andrew J Clifford, Gonzalo Rincon, Janel E Owens, Juan F Medrano, Alanna J Moshfegh, David J Baer and Janet A Novotny
    Citation: Lipids in Health and Disease 2013 12:66
  35. Pure 1, 3-diacylglycerols (1, 3-DAG) have been considered to be significant surfactants in food, cosmetics and pharmaceutical industries, as well as the effect on obesity prevention.

    Authors: Nanjing Zhong, Zhongyu Gui, Li Xu, Jianrong Huang, Kun Hu, Yongqing Gao, Xia Zhang, Zhenbo Xu, Jianyu Su and Bing Li
    Citation: Lipids in Health and Disease 2013 12:65
  36. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are functionally the most important omega-3 polyunsaturated fatty acids (PUFAs). Oral supply of these fatty acids increases their levels in plasma and...

    Authors: Omer Al-Taan, James A Stephenson, Laura Spencer, Cristina Pollard, Annette L West, Philip C Calder, Matthew Metcalfe and Ashley R Dennison
    Citation: Lipids in Health and Disease 2013 12:64
  37. The gene encoding diacylglycerol acyltransferase (DGAT1) is a functional and positional candidate gene for milk and intramuscular fat content. A bovine DGAT1 overexpression vector was constructed containing mouse...

    Authors: Feifei Yang, Zhuying Wei, Xiangbin Ding, Xinfeng Liu, Xiuguo Ge, Guimin Song, Guangpeng Li and Hong Guo
    Citation: Lipids in Health and Disease 2013 12:63
  38. Inflammation is a common feature in the majority of cardiovascular disease, including Diabetes Mellitus (DM). Levels of pro-inflammatory markers have been found in increasing levels in serum from diabetic pati...

    Authors: Antonio Gordillo-Moscoso, Emilio Ruiz, Manuel Carnero, Fernando Reguillo, Enrique Rodriguez, Teresa Tejerina and Santiago Redondo
    Citation: Lipids in Health and Disease 2013 12:62
  39. Prevalence of metabolic syndrome is high and increasing in China. The causation of this disorder is, yet, to be fully understood. Several studies with confirmatory factor analysis have been performed to invest...

    Authors: Da Huo, Wei Wang, Xia Li, Qi Gao, Lijuan Wu, Yanxia Luo, Youxin Wang, Puhong Zhang and Xiuhua Guo
    Citation: Lipids in Health and Disease 2013 12:61
  40. Keloids are common cutaneous pathological scars that are characterised by the histological accumulation of fibroblasts, collagen fibres, and clinically significant invasive growth. Although increasing lines of...

    Authors: Chenyu Huang and Rei Ogawa
    Citation: Lipids in Health and Disease 2013 12:60
  41. Previously, we demonstrated that trans fatty acid ingestion during pregnancy and lactation caused a pro-inflammatory effect on the newborn. The opposite effect was described for gestational prebiotic intake. I...

    Authors: Ana Claudia Losinskas Hachul, Laís Vales Vales Mennitti, Juliana Lopes Lopes de Oliveira, Mayara Franzoi Moreno, Marcos Hiromu Okuda, Bruno dos Santos, Lila Missae Oyama, Eliane Beraldi Ribeiro, Claudia Maria Oller do Nascimento and Luciana Pellegrini Pisani
    Citation: Lipids in Health and Disease 2013 12:59
  42. Intake of high-fat diet is associated with increased non-alcoholic fatty liver disease (NAFLD). Hepatic lipid accumulation and oxidative stress are key pathophysiological mechanisms in NAFLD. Both flaxseed oil...

    Authors: Jiqu Xu, Hui Gao, Lin Song, Wei Yang, Chang Chen, Qianchun Deng, Qingde Huang, Jin’e Yang and Fenghong Huang
    Citation: Lipids in Health and Disease 2013 12:58
  43. Adults born preterm at very low birth weight (VLBW ≤ 1500g) have increased risk factors for cardiovascular diseases including high blood pressure and impaired glucose regulation. Non-optimal lipoprotein profil...

    Authors: Petteri Hovi, Eero Kajantie, Pasi Soininen, Antti J Kangas, Anna-Liisa Järvenpää, Sture Andersson, Johan G Eriksson, Mika Ala-Korpela and Karoliina Wehkalampi
    Citation: Lipids in Health and Disease 2013 12:57
  44. Growth hormone (GH) and insulin signaling pathways are known important regulators of adipose homeostasis. The cross-talk between GH and insulin signaling pathways in mature adipocytes is poorly understood.

    Authors: Yuchao Zhang, Yuantao Liu, Xia Li, Weina Gao, Wenjie Zhang, Qingbo Guan, Jing Jiang, Stuart J Frank and Xiangdong Wang
    Citation: Lipids in Health and Disease 2013 12:56
  45. Women often lag behind men in their risk of cardiovascular events. However, with age and the onset of menopause, women’s cardiovascular risk eventually becomes similar to that of men. This change in risk may, ...

    Authors: Heidi T May, John R Nelson, Krishnaji R Kulkarni, Jeffrey L Anderson, Benjamin D Horne, Tami L Bair and Joseph B Muhlestein
    Citation: Lipids in Health and Disease 2013 12:55
  46. Insulin treatment can lead to good glycemic control and result in improvement of lipid parameters in type 2 diabetic patients. This study was designed to evaluate the effect of insulin analog initiation therap...

    Authors: Ibrahim Aslan, Ertan Kucuksayan and Mutay Aslan
    Citation: Lipids in Health and Disease 2013 12:54

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