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  1. Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and can vary from hepatic steatosis to end-stage liver disease. It is the most common liver disease and its preva...

    Authors: Essam M Hamad, Soad H Taha, Abdel-Gawad I Abou Dawood, Mahmoud Z Sitohy and Mahmoud Abdel-Hamid
    Citation: Lipids in Health and Disease 2011 10:57
    Content type: Research Published on:

  2. The ATP-binding cassette transporter A1 (ABCA1) is essential protein involved in lipid metabolism. The present study was undertaken to detect the possible association of polymorphisms in the ABCA1 gene [rs2230...

    Authors: Vana Kolovou, Genovefa Kolovou, Apostolia Marvaki, Agathi Karakosta, Georgios Vasilopoulos, Antonia Kalogiani, Dimitrios Degiannis, Christina Marvaki and Constantinos A Demopoulos
    Citation: Lipids in Health and Disease 2011 10:56
    Content type: Research Published on:

  3. The effect of food intake on caveolin expression in relation to insulin signalling was studied in skeletal muscle and adipocytes from retroperitoneal (RP) and subcutaneous (SC) adipose tissue, comparing fasted...

    Authors: Ana Gómez-Ruiz, Fermín I Milagro, Javier Campión, J Alfredo Martínez and Carlos de Miguel
    Citation: Lipids in Health and Disease 2011 10:55
    Content type: Research Published on:

  4. It is well known that lipids abnormally accumulate in the alveoli during idiopathic pulmonary alveolar proteinosis (PAP). It is unclear, however, whether lipids also abnormally accumulate in serum. This study ...

    Authors: Xinlun Tian, Jinmei Luo, Kai-Feng Xu, Lan Wang, Jiong Zhou, Ruie Feng, Yaosong Gui, Juan Wang, Wenbing Xu, Yi Xiao and Yuanjue Zhu
    Citation: Lipids in Health and Disease 2011 10:54
    Content type: Research Published on:

  5. Elevated plasma free fatty acid (FFA) levels have been linked to the development of atherosclerosis. However, how FFA causes atherosclerosis has not been determined. Because fatty acid translocase (FAT/CD36) i...

    Authors: Shuangtao Ma, Dachun Yang, De Li, Bing Tang and Yongjian Yang
    Citation: Lipids in Health and Disease 2011 10:53
    Content type: Research Published on:

  6. High-fat (HF) diet feeding usually leads to hyperphagia and body weight gain, but macronutrient proportions in the diet can modulate energy intake and fat deposition. The mechanisms of fat accumulation and mob...

    Authors: Maria E Estrany, Ana M Proenza, Isabel Lladó and Magdalena Gianotti
    Citation: Lipids in Health and Disease 2011 10:52
    Content type: Research Published on:

  7. A system that can deliver multi-drug at a prolonged rate is very important for the treatment of various chronic diseases such as diabetes, asthma and heart disease. Controlled porosity osmotic pump tablet (CPO...

    Authors: Rajagopal Kumaravelrajan, Nallaperumal Narayanan and Venkatesan Suba
    Citation: Lipids in Health and Disease 2011 10:51
    Content type: Research Published on:

  8. Heterozygous Familial Hypercholesterolemia (FH) is a genetic disorder characterized by a high risk of cardiovascular disease. Certain polymorphisms of the factor VII gene have been associated with the developm...

    Authors: Juan Criado-García, Francisco Fuentes, Cristina Cruz-Teno, Antonio García-Rios, Anabel Jiménez-Morales, Javier Delgado-Lista, Pedro Mata, Rodrigo Alonso, José López-Miranda and Francisco Pérez-Jiménez
    Citation: Lipids in Health and Disease 2011 10:50
    Content type: Research Published on:

  9. As an anti-TNF agent that targets inflammatory process directly, Pentoxifylline has been investigated for treatment of NASH in individual studies and pilot trials for years. We summarized the available informa...

    Authors: Wenjun Li, Liu Zheng, Chunjun Sheng, Xiaoyun Cheng, Liu Qing and Shen Qu
    Citation: Lipids in Health and Disease 2011 10:49
    Content type: Review Published on:

  10. The risk of coronary heart disease (CHD) is related to environmental factors and genetic variants. Apolipoprotein E (apoE) polymorphisms are heritable determinants of total and low-density lipoprotein choleste...

    Authors: Rui Baptista, Marta Rebelo, Joana Decq-Mota, Patrícia Dias, Pedro Monteiro, Luís A Providência and José M Silva
    Citation: Lipids in Health and Disease 2011 10:48
    Content type: Research Published on:

  11. Microvesicles isolated from body fluids are membrane - enclosed fragments of cell interior which carry information on the status of the organism. It is yet unclear how metabolism affects the number and composi...

    Authors: Vid Šuštar, Apolonija Bedina-Zavec, Roman Štukelj, Mojca Frank, Eva Ogorevc, Rado Janša, Keriya Mam, Peter Veranič and Veronika Kralj-Iglič
    Citation: Lipids in Health and Disease 2011 10:47
    Content type: Research Published on:

  12. Studies have shown that plasma high density lipoprotein cholesterol levels are negatively correlated with the development of atherosclerosis, whereas epidemiological studies have also shown that plasma sphingo...

    Authors: Nianlong Yan, Tingbo Ding, Jibin Dong, Yue Li and Manping Wu
    Citation: Lipids in Health and Disease 2011 10:46
    Content type: Research Published on:

  13. Aggressive clinical and public health interventions have resulted in significant reduction in coronary artery disease (CAD) worldwide. However, South Asian immigrants (SAIs) exhibit the higher prevalence of CA...

    Authors: Sunita Dodani, Rebecca Henkhaus, Jo Wick, James Vacek, Kamal Gupta, Lei Dong and Merlin G Butler
    Citation: Lipids in Health and Disease 2011 10:45
    Content type: Research Published on:

  14. Oxysterols are oxidation products of cholesterol that are generated by enzymatic reactions mediated by cytochrome P450 family enzymes or by non-enzymatic reactions involving reactive oxygen and nitrogen specie...

    Authors: Apinya Jusakul, Puangrat Yongvanit, Watcharin Loilome, Nisana Namwat and Rahul Kuver
    Citation: Lipids in Health and Disease 2011 10:44
    Content type: Review Published on:

  15. Dietary saturated fatty acids (SFAs) are generally considered to increase plasma cholesterol. It has also been claimed that they increase cardio-vascular disease, although the claim that some of SFAs can incre...

    Authors: Thierry Joël Nangue, Hilaire Macaire Womeni, Felicite Tchouanguep Mbiapo, Jacques Fanni and Linder Michel
    Citation: Lipids in Health and Disease 2011 10:43
    Content type: Research Published on:

  16. Post-traumatic ventilator-associated pneumonia (VAP) is a substantial clinical problem that increases hospital costs and typically adds to the duration of mechanical ventilation. We evaluated the impact of VAP...

    Authors: C Michael Dunham and Thomas J Chirichella
    Citation: Lipids in Health and Disease 2011 10:42
    Content type: Research Published on:

  17. In this study we investigated the antiatherogenic effect of dietary enrichment of a combination of extra virgin olive oil (EVO) and seal oil on apolipoprotein E-deficient (apoE-/-).

    Authors: Karl-Erik Eilertsen, Hanne K Mæhre, Katrien Cludts, Jan O Olsen and Marc F Hoylaerts
    Citation: Lipids in Health and Disease 2011 10:41
    Content type: Research Published on:

  18. The aim of the present study was to assess the effects of zinc or copper and polyphenolic compounds on the 8-isoprostaglandin F2α concentration in the serum and urine of rats with mammary cancer (adenocarcinoma) ...

    Authors: Barbara Bobrowska, Andrzej Tokarz, Sławomir Białek and Małgorzata Seweryn
    Citation: Lipids in Health and Disease 2011 10:40
    Content type: Research Published on:

  19. Chronic, low-grade inflammation provides a link between normal ageing and the pathogenesis of age-related diseases. A series of in vitro tests confirmed the strong anti-inflammatory activities of known inhibitors...

    Authors: Asaf A Qureshi, Julia C Reis, Nilofer Qureshi, Christopher J Papasian, David C Morrison and Daniel M Schaefer
    Citation: Lipids in Health and Disease 2011 10:39
    Content type: Research Published on:

  20. During the past decade, proprotein convertase subtilisin kexin type 9 (PCSK9) has been identified as a key regulator of serum LDL-cholesterol (LDL-C) levels. PCSK9 is secreted by the liver into the plasma and ...

    Authors: Robert J Konrad, Jason S Troutt and Guoqing Cao
    Citation: Lipids in Health and Disease 2011 10:38
    Content type: Review Published on:

  21. It is well known that high fat diets (HFDs) induce obesity and an increase in proinflammatory adipokines. Interleukin-6 (IL-6) is considered the major inflammatory mediator in obesity. Obesity is associated wi...

    Authors: Fábio S Lira, José C Rosa, Claudio A Cunha, Eliane B Ribeiro, Claudia Oller do Nascimento, Lila M Oyama and João F Mota
    Citation: Lipids in Health and Disease 2011 10:37
    Content type: Research Published on:

  22. Citrus flavonoids have been shown to decrease plasma lipid levels, improve glucose tolerance, and attenuate obesity. One possible mechanism underlying these physiological effects is reduction of hepatic levels...

    Authors: LaNita A Nichols, Daniel E Jackson, John A Manthey, Shivendra D Shukla and Lené J Holland
    Citation: Lipids in Health and Disease 2011 10:36
    Content type: Short report Published on:

  23. The role of pro-inflammatory lipids in systemic immune activation in HIV infection remains largely unknown. We hypothesized that HIV-1-infected persons on antiretroviral therapy would have pro-inflammatory hig...

    Authors: Theodoros Kelesidis, Otto O Yang, Judith S Currier, Kaveh Navab, Alan M Fogelman and Mohamad Navab
    Citation: Lipids in Health and Disease 2011 10:35
    Content type: Short report Published on:

  24. Several common genetic polymorphisms in the low density lipoprotein receptor (LDL-R) gene have associated with modifications of serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) leve...

    Authors: Xing-Jiang Long, Rui-Xing Yin, Ke-La Li, Wan-Ying Liu, Lin Zhang, Xiao-Li Cao, Lin Miao, Dong-Feng Wu, Lynn Htet Htet Aung and Xi-Jiang Hu
    Citation: Lipids in Health and Disease 2011 10:34
    Content type: Research Published on:

  25. Evidence of predictive power of various fatty acids on the risk of metabolic syndrome was scanty. We evaluated the role of various fatty acids, including saturated fat, monounsaturated fat, transfat, n-6 fatty...

    Authors: Kuo-Liong Chien, Chia-Lun Chao, Chen-Hong Kuo, Hung-Ju Lin, Pi-Hua Liu, Pei-Rony Chen, Hsiu-Ching Hsu, Bai-Chin Lee, Yuan-Teh Lee and Ming-Fong Chen
    Citation: Lipids in Health and Disease 2011 10:33
    Content type: Research Published on:

  26. Mammalian sPLA2-IB are well characterized. In contrast, much less is known about aquatic ones. The aquatic world contains a wide variety of living species and, hence represents a great potential for discoverin...

    Authors: Abir Ben Bacha, Aida Karray, Emna Bouchaala, Youssef Gargouri and Yassine Ben Ali
    Citation: Lipids in Health and Disease 2011 10:32
    Content type: Research Published on:

  27. Heme oxygenase-1 (HO-1), an antioxidant defense enzyme, has been shown to protect against oxidant-induced liver injury. However, its role on liver fibrosis remains unclear. This study aims to elucidate the eff...

    Authors: Rong Qi Wang, Yue Min Nan, Wen Juan Wu, Ling Bo Kong, Fang Han, Su Xian Zhao, Li Kong and Jun Yu
    Citation: Lipids in Health and Disease 2011 10:31
    Content type: Research Published on:

  28. In the present work we determined the total phenolic content of Aloe vera leaf skin (AVLS) extracts by using various solvents (hexane, chloroform-ethanol (1/1), ethyl acetate, butanol and water). We have also eva...

    Authors: Maher Kammoun, Sonia Miladi, Yassine Ben Ali, Mohamed Damak, Youssef Gargouri and Sofiane Bezzine
    Citation: Lipids in Health and Disease 2011 10:30
    Content type: Research Published on:

  29. Licorice flavonoid oil (LFO) has been reported to minimize visceral adipose tissue gain in obese mice and to result in a decrease in body weight and body fat in humans; the effects of which may be more pronoun...

    Authors: Zach W Bell, Robert E Canale and Richard J Bloomer
    Citation: Lipids in Health and Disease 2011 10:29
    Content type: Research Published on:

  33. In the water maze test, oral administration with 1,2-dilynoleoyl-sn-glycero-3-phosphocholine (DLPhtCho)(5 mg/kg) alone or DLPhtCho (5 mg/kg) plus 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPhtCho)(5 mg/k...

    Authors: Tetsu Nagata, Takahiro Yaguchi and Tomoyuki Nishizaki
    Citation: Lipids in Health and Disease 2011 10:25
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2015 14:115

  34. The turkey pancreatic lipase (TPL) was purified from delipidated pancreases. Some biochemical properties and kinetic studies were determined using emulsified system and monomolecular film techniques. Those stu...

    Authors: Madiha Bou Ali, Yassine Ben Ali, Aida Karray, Ahmed Fendri and Youssef Gargouri
    Citation: Lipids in Health and Disease 2011 10:24
    Content type: Research Published on:

  35. Treatment with atorvastatin (ATO) or dietary control has been demonstrated to benefit patients with non-alcoholic fatty liver disease (NAFLD) and hyperlipidemia. However, little is known on whether combination...

    Authors: Guiyuan Ji, Xihong Zhao, Liang Leng, Peiyi Liu and Zhuoqin Jiang
    Citation: Lipids in Health and Disease 2011 10:23
    Content type: Research Published on:

  36. Although lipids transfer through placenta is very limited, modification in dietary fatty acids can lead to implications in fetal and postnatal development. Trans fatty acid (TFA) intake during gestation and lacta...

    Authors: Juliana L de Oliveira, Lila M Oyama, Ana Cláudia L Hachul, Carolina Biz, Eliane B Ribeiro, Claudia M Oller do Nascimento and Luciana P Pisani
    Citation: Lipids in Health and Disease 2011 10:22
    Content type: Research Published on:

  37. Coronary angiography is the current standard method to evaluate coronary atherosclerosis in patients with suspected angina pectoris, but non-invasive CT scanning of the coronaries are increasingly used for the...

    Authors: Anne P Toft-Petersen, Hans H Tilsted, Jens Aarøe, Klaus Rasmussen, Thorkil Christensen, Bruce A Griffin, Inge V Aardestrup, Annette Andreasen and Erik B Schmidt
    Citation: Lipids in Health and Disease 2011 10:21
    Content type: Research Published on:

  38. Obesity, type 2 diabetes and hyperlipidemia frequently coexist and are associated with significantly increased morbidity and mortality. Consumption of refined carbohydrate and particularly fructose has increas...

    Authors: Danshan Huang, Tania Dhawan, Stephen Young, William H Yong, Laszlo G Boros and Anthony P Heaney
    Citation: Lipids in Health and Disease 2011 10:20
    Content type: Research Published on:

  40. Modification of fatty acids (FA) composition in erythrocytes lipids as an early indicator of the development of arterial hypertension (AH) and lipid disorders.

    Authors: Tatyana P Novgorodtseva, Tatyana A Kantur, Yulia K Karaman, Marina V Antonyuk and Natalia V Zhukova
    Citation: Lipids in Health and Disease 2011 10:18
    Content type: Review Published on:

  41. To investigate the effect of triglyceride (TG) integrates with plasma major components of apolipoproteins in HDL subclasses distribution and further elicited the TG-apolipoproteins (apos) interaction in the pr...

    Authors: Li Tian, Yanhua Xu, Mingde Fu, Tao Peng, Yinghui Liu and Shiyin Long
    Citation: Lipids in Health and Disease 2011 10:17
    Content type: Research Published on:

  42. Eicosanoids are major players in the pathogenesis of several common diseases, with either overproduction or imbalance (e.g. between thromboxanes and prostacyclins) often leading to worsening of disease symptoms. ...

    Authors: Olav A Christophersen and Anna Haug
    Citation: Lipids in Health and Disease 2011 10:16
    Content type: Review Published on:

  43. Trans fat are not desirable in many aspects on health maintenance. Low trans structured fats have been reported to be relatively more safe than trans fats.

    Authors: Yun-Young Cho, Eun-Young Kwon, Hye-Jin Kim, Seon-Min Jeon, Ki-Teak Lee and Myung-Sook Choi
    Citation: Lipids in Health and Disease 2011 10:15
    Content type: Short report Published on:

  44. Several genetic variants in the ATP-binding cassette transporter A1 (ABCA1) gene have associated with modifications of serum high-density lipoprotein cholesterol (HDL-C) levels and the susceptibility for coron...

    Authors: Xiao-Li Cao, Rui-Xing Yin, Dong-Feng Wu, Lin Miao, Lynn Htet Htet Aung, Xi-Jiang Hu, Qing Li, Ting-Ting Yan, Wei-Xiong Lin and Shang-Ling Pan
    Citation: Lipids in Health and Disease 2011 10:14
    Content type: Research Published on:

  45. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a recently identified and potentially useful plasma biomarker for cardiovascular and atherosclerotic diseases. However, the correlation between the Lp-PLA2 act...

    Authors: Hui-ping Gong, Yi-meng Du, Li-na Zhong, Zhao-qiang Dong, Xin Wang, Yong-jun Mao and Qing-hua Lu
    Citation: Lipids in Health and Disease 2011 10:13
    Content type: Research Published on:

  46. Visceral Fat Area (VFA) is an independent predictor of coronary disease. While low density lipoprotein cholesterol (LDL-C) is used to determine risk and guide therapy, its accuracy fails in obese patients who ...

    Authors: Michel R Hoenig, Gary Cowin, Raymond Buckley, Christine McHenery and Allan Coulthard
    Citation: Lipids in Health and Disease 2011 10:12
    Content type: Research Published on:

  47. Adiponectin is the most abundant plasma protein synthesized for the most part in adipose tissue, and it is an insulin-sensitive hormone, playing a central role in glucose and lipid metabolism. In addition, it ...

    Authors: Cristiane de Oliveira, Ana BM de Mattos, Carolina Biz, Lila M Oyama, Eliane B Ribeiro and Cláudia Maria Oller do Nascimento
    Citation: Lipids in Health and Disease 2011 10:11
    Content type: Research Published on:

  48. n-3 and n-6 polyunsaturated fatty acids (PUFAs) are the two major classes of PUFAs encountered in the diet, and both classes of fatty acids are required for normal human health. Moreover, PUFAs have effects on di...

    Authors: Maria Notarnicola, Caterina Messa, Maria G Refolo, Valeria Tutino, Angelica Miccolis and Maria G Caruso
    Citation: Lipids in Health and Disease 2011 10:10
    Content type: Research Published on:

  49. The Roma (Gypsies) are a transnational minority, founder population characterized by unique genetic background modeled by culturally determined endogamy. The present study explores whether the widely found car...

    Authors: Hrvojka Marija Zeljko, Tatjana Škarić-Jurić, Nina Smolej Narančić, Željka Tomas, Ana Barešić, Marijana Peričić Salihović, Boris Starčević and Branka Janićijević
    Citation: Lipids in Health and Disease 2011 10:9
    Content type: Short report Published on:

  50. Statins are first-line pharmacotherapeutic agents for hypercholesterolemia treatment in humans. However the effects of statins on atherosclerosis in mouse models are very paradoxical. In this work, we wanted t...

    Authors: Guohua Song, Jia Liu, Zhenmei Zhao, Yang Yu, Hua Tian, Shutong Yao, Guoli Li and Shucun Qin
    Citation: Lipids in Health and Disease 2011 10:8
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X