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  1. High-density lipoproteins (HDL) and their main apolipoprotein, apoA-I, exhibit anti-inflammatory properties. The development of peptides that mimic HDL apolipoproteins offers a promising strategy to reduce inf...

    Authors: Belinda A Di Bartolo, Laura Z Vanags, Joanne TM Tan, Shisan Bao, Kerry-Anne Rye, Philip J Barter and Christina A Bursill
    Citation: Lipids in Health and Disease 2011 10:224
    Content type: Research Published on:

  2. Evidence suggests that physical activity (PA) has a beneficial effect on high-density lipoprotein cholesterol (HDL) and triglycerides. However, observational studies show contrasting results for this associati...

    Authors: Jeroen SL de Munter, Irene G van Valkengoed, Karien Stronks and Charles Agyemang
    Citation: Lipids in Health and Disease 2011 10:223
    Content type: Research Published on:

  3. Synthetic activators of peroxisome proliferator-activated receptors (PPARs) stimulate cholesterol removal from macrophages through PPAR-dependent up-regulation of liver × receptor α (LXRα) and subsequent induc...

    Authors: Ines Kämmerer, Robert Ringseis, Ronald Biemann, Gaiping Wen and Klaus Eder
    Citation: Lipids in Health and Disease 2011 10:222
    Content type: Research Published on:

  4. Bacterial lipases received much attention for their substrate specificity and their ability to function in extreme environments (pH, temperature...). Many staphylococci produced lipases which were released int...

    Authors: Slim Cherif, Sami Mnif, Fatma Hadrich, Slim Abdelkafi and Sami Sayadi
    Citation: Lipids in Health and Disease 2011 10:221
    Content type: Research Published on:

  5. Aging and dyslipidemia are processes which can lead to deleterious consequences to renal function. Therefore, the aim of this study was to determine the effects of both hypercholesterolemia and aging on renal ...

    Authors: Camille M Balarini, Mariana ZT Oliveira, Thiago MC Pereira, Nyam F Silva, Elisardo C Vasquez, Silvana S Meyrelles and Agata L Gava
    Citation: Lipids in Health and Disease 2011 10:220
    Content type: Research Published on:

  6. Among the digestive enzymes, phospholipase A2 (PLA2) hydrolyzes the essential dietary phospholipids in marine fish and shellfish. However, we know little about the organs that produce PLA2, and the ontogeny of th...

    Authors: Zied Zarai, Nicholas Boulais, Pascale Marcorelles, Eric Gobin, Sofiane Bezzine, Hafedh Mejdoub and Youssef Gargouri
    Citation: Lipids in Health and Disease 2011 10:219
    Content type: Research Published on:

  7. Previous studies have demonstrated that long chain fatty acids influence fibroblast function at sub-lethal concentrations. This study is the first to assess the effects of oleic, linoleic or palmitic acids on ...

    Authors: Juliana Magdalon, Elaine Hatanaka, Talita Romanatto, Hosana G Rodrigues, Wilson MT Kuwabara, Caitriona Scaife, Philip Newsholme and Rui Curi
    Citation: Lipids in Health and Disease 2011 10:218
    Content type: Research Published on:

  8. Obese subjects with impaired glucose tolerance (IGT) are more susceptible than healthy individuals to oxidative stress and cardiovascular disease. This randomised controlled investigation was designed to test ...

    Authors: Andrea M McNeilly, Gareth W Davison, Marie H Murphy, Nida Nadeem, Tom Trinick, Ellie Duly, Anna Novials and Jane McEneny
    Citation: Lipids in Health and Disease 2011 10:217
    Content type: Research Published on:

  10. We investigated relationship of low levels of high density lipoprotein cholesterol (HDL-C), high levels of triglycerides, and renal function for the odds, prognosis and survival following acute coronary events...

    Authors: Kuo-Liong Chien, Hung-Ju Lin, Hsiu-Ching Hsu and Ming-Fong Chen
    Citation: Lipids in Health and Disease 2011 10:215
    Content type: Research Published on:

  11. To develop effective strategies in cancer chemoprevention, an increased understanding of endogenous biochemical mediators that block metastatic processes is critically needed. Dietary lipids and non-steroidal ...

    Authors: Paul L Wood, M Amin Khan, Tara Smith and Dayan B Goodenowe
    Citation: Lipids in Health and Disease 2011 10:214
    Content type: Research Published on:

  12. Platelet activating factor (PAF) has been proposed as a key factor and initial trigger in atherosclerosis. Recently, a modulation of PAF metabolism by bioactive food constituents has been suggested. In this st...

    Authors: Constantina Nasopoulou, Alexandros B Tsoupras, Haralabos C Karantonis, Constantinos A Demopoulos and Ioannis Zabetakis
    Citation: Lipids in Health and Disease 2011 10:213
    Content type: Research Published on:

  14. Since the early 1990s, several strains of genetically modified mice have been developed as models for experimental atherosclerosis. Among the available models, the apolipoprotein E-deficient (apoE-/-) mouse is of...

    Authors: Silvana S Meyrelles, Veronica A Peotta, Thiago MC Pereira and Elisardo C Vasquez
    Citation: Lipids in Health and Disease 2011 10:211
    Content type: Review Published on:

  15. Probucol is a unique hypolipidemic agent that decreases high density lipoprotein cholesterol (HDL-C). However, it is not definite that whether probucol hinders the progression of atherosclerosis by improving H...

    Authors: Jian-Kai Zhong, Zhi-Gang Guo, Chen Li, Zhen-Kun Wang, Wen-Yan Lai and Yan Tu
    Citation: Lipids in Health and Disease 2011 10:210
    Content type: Research Published on:

  16. Extracellular bacterial lipases received much attention for their substrate specificity and their ability to function under extreme environments (pH, temperature...). Many staphylococci produced lipases which ...

    Authors: Slim Cherif, Sami Mnif, Fatma Hadrich, Slim Abdelkafi and Sami Sayadi
    Citation: Lipids in Health and Disease 2011 10:209
    Content type: Research Published on:

  18. Liver dominates the production and secretion of apolipoprotein B (apoB) and evidence shows that liver malfunction induced by hepatitis B virus (HBV) infection could lead to apolipoprotein metabolism disorders....

    Authors: Fu-Bing Wang, Cheng-liang Zhu, Xinghui Liu and Guo-sheng Gao
    Citation: Lipids in Health and Disease 2011 10:207
    Content type: Research Published on:

  19. Apolipoprotein E (apoE) is a key component of the lipid metabolism. Polymorphisms at the apoE gene (APOE) have been associated with cardiovascular disease, lipid levels and lipid-lowering response to statins. We ...

    Authors: Alvaro Cerda, Fabiana DV Genvigir, Maria AV Willrich, Simone S Arazi, Marcia MS Bernik, Egidio L Dorea, Marcelo C Bertolami, Andre A Faludi, Mario H Hirata and Rosario DC Hirata
    Citation: Lipids in Health and Disease 2011 10:206
    Content type: Research Published on:

  21. This study evaluated the relationship between ulcerative colitis and obesity, which are both chronic diseases characterized by inflammation and increases in immune cells and pro-inflammatory cytokines.

    Authors: Lílian G Teixeira, Alda J Leonel, Edenil C Aguilar, Nathália V Batista, Andréa C Alves, Candido C Coimbra, Adaliene VM Ferreira, Ana Maria C de Faria, Denise C Cara and Jacqueline I Alvarez Leite
    Citation: Lipids in Health and Disease 2011 10:204
    Content type: Research Published on:

  22. Long and persistent uncontrolled diabetes tends to degenerate the immune system and leads to an increased incidence of infection. Whey proteins (WPs) enhance immunity during early life and have a protective ro...

    Authors: Gamal Badr, Mohamed Mohany and Ali Metwalli
    Citation: Lipids in Health and Disease 2011 10:203
    Content type: Research Published on:

  23. Nonalcoholic fatty liver disease (NAFLD) is emerging as the most common liver disease of industrialized countries. Thus, discovering food components that can ameliorate NAFLD is of interest. Lotus root, the ed...

    Authors: Yumi Tsuruta, Koji Nagao, Shunichi Kai, Keisuke Tsuge, Takashi Yoshimura, Kazuyoshi Koganemaru and Teruyoshi Yanagita
    Citation: Lipids in Health and Disease 2011 10:202
    Content type: Research Published on:

  24. One of the well-defined and characterized protein modifications usually produced by oxidation is carbonylation, an irreversible non-enzymatic modification of proteins. However, carbonyl groups can be introduce...

    Authors: Rafael Medina-Navarro, Renato Nieto-Aguilar and Cleto Alvares-Aguilar
    Citation: Lipids in Health and Disease 2011 10:201
    Content type: Research Published on:

  25. Several polymorphisms in the apolipoprotein C3 (APOC3) gene have been found association with hypertriglyceridemia(HTG), but the link with coronary heart disease(CHD) risk between ethnicities was still controve...

    Authors: Juan Yu, Jingjing Huang, Yan Liang, Baodong Qin, Su He, Jing Xiao, Huimin Wang and Renqian Zhong
    Citation: Lipids in Health and Disease 2011 10:200
    Content type: Research Published on:

  26. Apolipoprotein M (apoM) may have potential antiatherosclerotic properties. It has been reported that apoM expression could be regulated by many intracellar and extracellar factors. In the present study we furt...

    Authors: Chunhua Zhu, Dongmei Di, Xiaoying Zhang, Guanghua Luo, Zongchun Wang, Jiang Wei, Yuanping Shi, Maria Berggren-Söderlund, Peter Nilsson-Ehle and Ning Xu
    Citation: Lipids in Health and Disease 2011 10:199
    Content type: Research Published on:

  27. Obesity is characterized by increased cell death and inflammatory reactions in the adipose tissue. Here, we explored pathophysiological alterations taking place in the adipose tissue in long-standing obesity. ...

    Authors: Mehmet M Altintas, Maria A Rossetti, Behzad Nayer, Alvaro Puig, Patricia Zagallo, Luis M Ortega, Kevin B Johnson, George McNamara, Jochen Reiser, Armando J Mendez and Ali Nayer
    Citation: Lipids in Health and Disease 2011 10:198
    Content type: Research Published on:

  28. Hepatic lipase (HL), an enzyme present in the hepatic sinusoids, is responsible for the lipolysis of lipoproteins. Human HL contains four polymorphic sites: G-250A, T-710C, A-763G, and C-514T single-nucleotide...

    Authors: Alvaro Pulchinelli Jr, Ana Maria Massad Costa, Cristina V de Carvalho, Naiara Correa Nogueira de Souza, Mauro A Haidar, Adagmar Andriolo and Ismael DC Guerreiro da Silva
    Citation: Lipids in Health and Disease 2011 10:197
    Content type: Research Published on:

  30. One particularly exciting field of research involves the use of gold nanoparticles (GNPs) in the detection and treatment of cancer cells in the liver. The detection and treatment of cancer is an area in which ...

    Authors: Mohamed Anwar K Abdelhalim and Mohsen Mahmoud Mady
    Citation: Lipids in Health and Disease 2011 10:195
    Content type: Research Published on:

  31. Alterations of endocannabinoid system in adipose tissue play an important role in lipid regulation and metabolic dysfunction associated with obesity. The purpose of this study was to determine whether gene exp...

    Authors: Tongjian You, Beth L Disanzo, Xuewen Wang, Rongze Yang and Dawei Gong
    Citation: Lipids in Health and Disease 2011 10:194
    Content type: Research Published on:

  32. Obesity, insulin resistance and hyperandrogenism, crucial parameters of Polycystic ovary syndrome (PCOS) play significant pathophysiological roles in lipidemic aberrations associated within the syndrome. Parts...

    Authors: Muammer Karadeniz, Mehmet Erdoğan, Zengi Ayhan, Murat Yalcın, Murat Olukman, Sevki Cetinkalp, Gulinnaz E Alper, Zuhal Eroglu, Asli Tetik, Vildan Cetintas, Ahmet G Ozgen, Fusun Saygılı and Candeger Yılmaz
    Citation: Lipids in Health and Disease 2011 10:193
    Content type: Research Published on:

  33. To correlate lipid metabolism and autonomic dysfunction with anxious-depressive spectrum and eating disorders. To propose the lipid index (LI) as a new possible biomarker.

    Authors: Elisabetta Pistorio, Maria Luca, Antonina Luca, Vincenzo Messina and Carmela Calandra
    Citation: Lipids in Health and Disease 2011 10:192
    Content type: Research Published on:

  34. Blood viscosity appears to be independent predictor of stroke, carotid intima-media thickening, atherosclerosis and most cardiovascular diseases. In an attempt to understand the toxicity and the potential thre...

    Authors: Mohamed Anwar K Abdelhalim
    Citation: Lipids in Health and Disease 2011 10:191
    Content type: Research Published on:

  35. Previous reports have shown an antiproliferative effect of the synthetic, 3-thia fatty acid tetradecylthioacetic acid (TTA) on different cancer cells in vitro and in vivo. The mechanisms behind the observed effec...

    Authors: Anne G Lundemo, Caroline HH Pettersen, Kjetil Berge, Rolf K Berge and Svanhild A Schønberg
    Citation: Lipids in Health and Disease 2011 10:190
    Content type: Research Published on:

  36. Hyperlipidemia associated with obesity is closely related to the development of atherosclerosis. Both n-3 polyunsaturated fatty acids (PUFAs) and long-chain monounsaturated fatty acids (MUFAs; i.e., C20:1 and ...

    Authors: Zhi-Hong Yang, Hiroko Miyahara, Jiro Takeo, Akimasa Hatanaka and Masashi Katayama
    Citation: Lipids in Health and Disease 2011 10:189
    Content type: Research Published on:

  37. The effect of exercise training on the fatty acid composition of erythrocyte membranes was evaluated in an experimental animal model where rats were subjected to a ten-wk aerobic training. Five groups of rats ...

    Authors: Marina Marini, Provvidenza M Abruzzo, Alessandra Bolotta, Arsenio Veicsteinas and Carla Ferreri
    Citation: Lipids in Health and Disease 2011 10:188
    Content type: Short report Published on:

  38. To examine the effects on LDL cholesterol of the combined use of statins and phytosterols/-stanols, in vivo studies and clinical trials are necessary. However, for a better interpretation of the experimental d...

    Authors: Simone RBM Eussen, Cathy JM Rompelberg, Olaf H Klungel and Jan CH van Eijkeren
    Citation: Lipids in Health and Disease 2011 10:187
    Content type: Research Published on:

  39. The plasma lipoprotein response of F1B Golden-Syrian hamsters fed diets high in very long chain (VLC) n-3 polyunsaturated fatty acids (PUFA) is paradoxical to that observed in humans. This anomaly is attribute...

    Authors: Jaime L Lecker, Nirupa R Matthan, Jeffrey T Billheimer, Daniel J Rader and Alice H Lichtenstein
    Citation: Lipids in Health and Disease 2011 10:186
    Content type: Research Published on:

  40. Myeloperoxidase (MPO) is a marker of plaque vulnerability and a mechanistic bridge between inflammation and cardiovascular disease, and thus is a suitable target for therapeutic strategy against cardiovascular...

    Authors: Mariarita Puntoni, Francesco Sbrana, Federico Bigazzi, Fabrizio Minichilli, Ezio Ferdeghini and Tiziana Sampietro
    Citation: Lipids in Health and Disease 2011 10:185
    Content type: Research Published on:

  41. Dietary polyunsaturated fats increase liver injury in response to ethanol feeding. We evaluated the effect of dietary corn oil (CO), olive oil (OO), and beef tallow (BT) on fatty acid composition of liver micr...

    Authors: Jinah Hwang, Yun-Hee Chang, Jung Hwa Park, Soo Yeon Kim, Haeyon Chung, Eugene Shim and Hye Jin Hwang
    Citation: Lipids in Health and Disease 2011 10:184
    Content type: Research Published on:

  42. The Visceral Adiposity Index (VAI) is a sex-specific mathematical index, based on Waist Circumference (WC), Body Mass Index (BMI), triglycerides (TG) and HDL cholesterol (HDL) levels, indirectly expressing vis...

    Authors: Marco C Amato, Carla Giordano, Maria Pitrone and Aldo Galluzzo
    Citation: Lipids in Health and Disease 2011 10:183
    Content type: Research Published on:

  43. Childhood peroxisomal disorders and leukodystrophies are devastating diseases characterized by dysfunctional lipid metabolism. Plasmalogens (ether glycerophosphoethanolamine lipids) are decreased in these gene...

    Authors: Paul L Wood, M Amin Khan, Tara Smith, Greg Ehrmantraut, Wei Jin, Wei Cui, Nancy E Braverman and Dayan B Goodenowe
    Citation: Lipids in Health and Disease 2011 10:182
    Content type: Research Published on:

  44. Postprandial lipemia (PPL) is likely a risk factor for cardiovascular disease but these changes have not been well described and characterized in a large cohort. We assessed acute changes in the size and conce...

    Authors: Mary K Wojczynski, Stephen P Glasser, Albert Oberman, Edmond K Kabagambe, Paul N Hopkins, Michael Y Tsai, Robert J Straka, Jose M Ordovas and Donna K Arnett
    Citation: Lipids in Health and Disease 2011 10:181
    Content type: Research Published on:

  45. This study aimed to determine if 25 days of canola oil intake in the absence of excess dietary salt or together with salt loading affects antioxidant and oxidative stress markers in the circulation. A further ...

    Authors: Annateresa Papazzo, Xavier Conlan, Louise Lexis and Paul Lewandowski
    Citation: Lipids in Health and Disease 2011 10:180
    Content type: Research Published on:

  46. Numerous health benefits associated with increased omega-3 polyunsaturated fatty acid (n-3 PUFA) consumption has lead to an increasing variety of available n-3 PUFA sources. However, sources differ in the type...

    Authors: Janet C Tou, Stephanie N Altman, Joseph C Gigliotti, Vagner A Benedito and Elizabeth L Cordonier
    Citation: Lipids in Health and Disease 2011 10:179
    Content type: Research Published on:

  47. The objective of the present study was to examine the influence of adding various amounts beetroot (Beta vulgaris) crisps on gastrointestinal function, antioxidant status and blood and liver lipid profiles in a h...

    Authors: Monika Wroblewska, Jerzy Juskiewicz and Wieslaw Wiczkowski
    Citation: Lipids in Health and Disease 2011 10:178
    Content type: Research Published on:

  48. Inflammation has been implicated in a variety of diseases associated with ageing, including cancer, cardiovascular, and neurologic diseases. We have recently established that the proteasome is a pivotal regula...

    Authors: Asaf A Qureshi, Xiaoyu Tan, Julia C Reis, Mostafa Z Badr, Christopher J Papasian, David C Morrison and Nilofer Qureshi
    Citation: Lipids in Health and Disease 2011 10:177
    Content type: Research Published on:

  50. Epidemiologic studies indicate a strong inverse correlation between plasma levels of high-density lipoproteins (HDL) and cardiovascular disease (CVD). The most relevant cardioprotective mechanism mediated by H...

    Authors: Santiago Redondo, José Martínez-González, Concha Urraca and Teresa Tejerina
    Citation: Lipids in Health and Disease 2011 10:175
    Content type: Review Published on:
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Lipids in Health and Disease

ISSN: 1476-511X