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  1. Adiponectin is the most abundant plasma protein synthesized for the most part in adipose tissue, and it is an insulin-sensitive hormone, playing a central role in glucose and lipid metabolism. In addition, it ...

    Authors: Cristiane de Oliveira, Ana BM de Mattos, Carolina Biz, Lila M Oyama, Eliane B Ribeiro and Cláudia Maria Oller do Nascimento
    Citation: Lipids in Health and Disease 2011 10:11
    Content type: Research Published on:

  2. Sphingomyelin synthase 2 (SMS2) contributes to de novo sphingomyelin (SM) biosynthesis. Its activity is related to SM levels in the plasma and the cell membrane. In this study, we investigated the possibility ...

    Authors: Xiaogang Wang, Jibin Dong, Yarui Zhao, Yue Li and Manping Wu
    Citation: Lipids in Health and Disease 2011 10:7
    Content type: Research Published on:

  3. Obesity became major health problem in the world, the objective of this work was to examine the effect of high sucrose and high fat diet to induce obesity on antioxidant defense system, biochemical changes in ...

    Authors: Kamal A Amin, Hamdy H Kamel and Mohamed A Abd Eltawab
    Citation: Lipids in Health and Disease 2011 10:6
    Content type: Research Published on:

  4. Proprotein convertase subtilisin-like kexin type 9 (PCSK9) plays a key role in regulating plasma low-density lipoprotein cholesterol (LDL-C) levels. However, the association of E670G (rs505151) polymorphism in...

    Authors: Lynn Htet Htet Aung, Rui-Xing Yin, Lin Miao, Xi-Jiang Hu, Ting-Ting Yan, Xiao-Li Cao, Dong-Feng Wu, Qing Li, Shang-Ling Pan and Jin-Zhen Wu
    Citation: Lipids in Health and Disease 2011 10:5
    Content type: Research Published on:

  5. The presence of chicken group-IIA PLA2 (ChPLA2-IIA) in the intestinal secretion suggests that this enzyme plays an important role in systemic bactericidal defence. We have analyzed the bactericidal activity of...

    Authors: Aida Karray, Yassine Ben Ali, Youssef Gargouri and Sofiane Bezzine
    Citation: Lipids in Health and Disease 2011 10:4
    Content type: Research Published on:

  6. Metabolic syndrome is a disease that today affects millions of people around the world. Therefore, it is of great interest to implement more effective procedures for preventing and treating this disease. In se...

    Authors: Ana C Ghezzi, Lucieli T Cambri, Carla Ribeiro, José D Botezelli and Maria AR Mello
    Citation: Lipids in Health and Disease 2011 10:3
    Content type: Research Published on:

  7. Inflammation process plays an important role in the development of atherosclerosis. Hypercholesterolemia is one of the major risk factors for atherosclerosis. The present study aimed to evaluate the effect of ...

    Authors: Adel A Amran, Zaiton Zakaria, Faizah Othman, Srijit Das, Hesham M Al-Mekhlafi and Nor-Anita MM Nordin
    Citation: Lipids in Health and Disease 2011 10:2
    Content type: Research Published on:

  8. Oxidized low-density lipoprotein (oxLDL) uptake by macrophages plays an important role in foam cell formation. It has been suggested the presence of heterogeneous subsets of macrophage, such as M1 and M2, in h...

    Authors: Kuniaki Hirose, Kazuhisa Iwabuchi, Kazunori Shimada, Takashi Kiyanagi, Chihiro Iwahara, Hitoshi Nakayama and Hiroyuki Daida
    Citation: Lipids in Health and Disease 2011 10:1
    Content type: Research Published on:

  9. To report changes in body weight, total and central fat mass, metabolic, hormonal and inflammatory parameters in overweight people who participated in a six months weight loss intervention associating diet man...

    Authors: Frédéric Dutheil, Bruno Lesourd, Daniel Courteix, Robert Chapier, Eric Doré and Gérard Lac
    Citation: Lipids in Health and Disease 2010 9:148
    Content type: Research Published on:

  10. Oxidized low-density lipoprotein (LDL) may act as an atheroprotective (anti-atherosclerotic) agent under some conditions. While the α1-antitrypsin (AT)-LDL complex is considered a type of oxidized LDL, its cli...

    Authors: Kazuhiko Kotani, Toshiyuki Yamada and Nobuyuki Taniguchi
    Citation: Lipids in Health and Disease 2010 9:147
    Content type: Research Published on:

  11. Abnormalities in lipid metabolism and transport are hallmarks in analbuminemic Nagase rats (NAR) and humans. Triglyceridemia is nearly 3- to 5-fold higher in female NAR than in control Sprague-Dawley rats (SDR...

    Authors: Tiago R Figueira, Aníbal E Vercesi and Helena CF Oliveira
    Citation: Lipids in Health and Disease 2010 9:146
    Content type: Research Published on:

  12. The association of peroxisome proliferator-activated receptor delta (PPARD) +294T > C polymorphism and serum lipid levels is inconsistent in several previous studies. Bai Ku Yao is an isolated subgroup of the ...

    Authors: Lin Miao, Rui-Xing Yin, Dong-Feng Wu, Xiao-Li Cao, Qing Li, Xi-Jiang Hu, Ting-Ting Yan, Lynn Htet Htet Aung, De-Zhai Yang and Wei-Xiong Lin
    Citation: Lipids in Health and Disease 2010 9:145
    Content type: Research Published on:

  13. Type 2 diabetes is associated with significant cardiovascular morbidity and mortality. Although low-density lipoprotein cholesterol levels may be normal in patients with type 2 diabetes, insulin resistance dri...

    Authors: Krishnaswami Vijayaraghavan
    Citation: Lipids in Health and Disease 2010 9:144
    Content type: Review Published on:

  14. Inflammation has been implicated in cardiovascular disease, and the important role of proteasomes in the development of inflammation and other macrophage functions has been demonstrated. Tocotrienols are poten...

    Authors: Asaf A Qureshi, Julia C Reis, Christopher J Papasian, David C Morrison and Nilofer Qureshi
    Citation: Lipids in Health and Disease 2010 9:143
    Content type: Research Published on:

  15. Statins induces cell cycle arrest, apoptosis, reduction of angiogenic factors, inhibition of the endothelial growth factor, impairing tissue adhesion and attenuation of the resistance mechanisms. The aim of th...

    Authors: Giovani M Favero, Michel F Otuki, Karen A Oliveira, Milton S Bohatch Jr, Primavera Borelli, Francisco E Barros, Durvanei A Maria, Daniel Fernandes and Sergio P Bydlowski
    Citation: Lipids in Health and Disease 2010 9:142
    Content type: Research Published on:

  17. Because abdominal obesity is predisposed to various metabolic disorders, it is of major importance to assess and track the changes with time of this specific fat mass. The main issue for clinicians or research...

    Authors: Maude Gerbaix, Lore Metz, Emeline Ringot and Daniel Courteix
    Citation: Lipids in Health and Disease 2010 9:140
    Content type: Research Published on:

  18. The association of rs1044925 polymorphism in the acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) gene and serum lipid profiles is not well known in different ethnic groups. Bai Ku Yao is a special subgroup of ...

    Authors: Dong-Feng Wu, Rui-Xing Yin, Lynn Htet Htet Aung, Xi-Jiang Hu, Xiao-Li Cao, Lin Miao, Qing Li, Ting-Ting Yan, Jin-Zhen Wu and Shang-Ling Pan
    Citation: Lipids in Health and Disease 2010 9:139
    Content type: Research Published on:

  19. The aim of the present study was to examine how lipid profiles are associated with insulin resistance in Japanese community-dwelling adults.

    Authors: Ryuichi Kawamoto, Yasuharu Tabara, Katsuhiko Kohara, Tetsuro Miki, Tomo Kusunoki, Shuzo Takayama, Masanori Abe, Tateaki Katoh and Nobuyuki Ohtsuka
    Citation: Lipids in Health and Disease 2010 9:138
    Content type: Research Published on:

  20. Rapeseed oil is the principal dietary source of monounsaturated and n-3 polyunsaturated fatty acids in the Northern Europe. However, the effect of rapeseed oil on the markers of subclinical atherosclerosis is ...

    Authors: Ari Palomäki, Hanna Pohjantähti-Maaroos, Marja Wallenius, Päivi Kankkunen, Heikki Aro, Sari Husgafvel, Juha-Matti Pihlava and Kalevi Oksanen
    Citation: Lipids in Health and Disease 2010 9:137
    Content type: Research Published on:

  21. Some patients administered cholesterol-lowering therapies may experience an increase in the proportion of small LDL particles, which may be misinterpreted as a worsening of atherosclerotic coronary heart disea...

    Authors: Harold Bays, Scott Conard, Lawrence A Leiter, Steven Bird, Erin Jensen, Mary E Hanson, Arvind Shah and Andrew M Tershakovec
    Citation: Lipids in Health and Disease 2010 9:136
    Content type: Research Published on:

  22. PUFAs are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme catalyzing the conversion of HMGCoA to mevalonate, the rate limiting step in cholesterol biosynthesis. Statin...

    Authors: Maria Notarnicola, Caterina Messa, Maria G Refolo, Valeria Tutino, Angelica Miccolis and Maria G Caruso
    Citation: Lipids in Health and Disease 2010 9:135
    Content type: Research Published on:

  23. Kurozu concentrated liquid (KCL) is used as a health-promoting supplement for the treatment of disorders such as cancer, hyperlipidemia, and hypertension in Japan. We investigated the possible anti-obesity eff...

    Authors: Li-Tao Tong, Yoshinori Katakura, Sayaka Kawamura, Sanae Baba, Yasutake Tanaka, Miyako Udono, Yoshie Kondo, Kumi Nakamura, Katsumi Imaizumi and Masao Sato
    Citation: Lipids in Health and Disease 2010 9:134
    Content type: Research Published on:

  24. Despite significant improvements in the treatment of coronary heart disease (CHD), it is still a major cause of mortality and morbidity among the Iranian population. Epidemiological studies have documented tha...

    Authors: Teymoor Yary, Kourosh Soleimannejad, Firdaus Abd Rahim, Mirnalini Kandiah, Sanaz Aazami, Seyedehozma Jafar Poor, Wong Teck Wee and Golnaz Aazami
    Citation: Lipids in Health and Disease 2010 9:133
    Content type: Research Published on:

  25. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive glucocorticoids to active glucocorticoids and plays an important role in the development of obesity and metabolic syndrom...

    Authors: Sakamuri SS Vara Prasad, Anamthathmakula Prashanth, Chodavarapu Pavan Kumar, Sirisha J Reddy, Nappan V Giridharan and Ayyalasomayajula Vajreswari
    Citation: Lipids in Health and Disease 2010 9:132
    Content type: Short paper Published on:

  26. It is designed to investigate the effects of combination therapy of allicin and fenofibrate on the endothelial and liver functions in rats with hyperlipidemia.

    Authors: Weihong Li, Daxin Wang, Guohua Song, Chunxia Zuo, Xianfu Qiao and Shucun Qin
    Citation: Lipids in Health and Disease 2010 9:131
    Content type: Research Published on:

  27. The high incidence of insulin resistance and the metabolic syndrome in South Asians remains unexplained. I propose that a defect in the activity of Δ6 and Δ5 desaturases and consequent low plasma and tissue conce...

    Authors: Undurti N Das
    Citation: Lipids in Health and Disease 2010 9:130
    Content type: Hypothesis Published on:

  28. Dysregulated inflammation in cystic fibrosis (CF) is attributed to an altered production of inflammatory mediators derived from polyunsaturated lipids. In comparison to the arachidonic acid (AA) cascade, littl...

    Authors: Elena Bravo, Mariarosaria Napolitano, Sara Benedetti Valentini and Serena Quattrucci
    Citation: Lipids in Health and Disease 2010 9:129
    Content type: Short paper Published on:

  29. Cardiovascular diseases (CVD) are the main cause of death and disability in developed countries. In most cases, the progress of CVD is influenced by environmental factors and multifactorial inheritance. The pu...

    Authors: Rafael O Alvim, Silvia RS Freitas, Noely E Ferreira, Paulo CJL Santos, Roberto S Cunha, José G Mill, José E Krieger and Alexandre C Pereira
    Citation: Lipids in Health and Disease 2010 9:128
    Content type: Research Published on:

  30. This post-hoc analysis compared the lipid-altering efficacy of Ezetimibe/Simvastatin 10/20 mg (EZ/Simva) versus Rosuvastatin 10 mg (Rosuva) in patients stratified by statin potency/dose prior to randomization.

    Authors: Margus Viigimaa, Helena Vaverkova, Michel Farnier, Maurizio Averna, Luc Missault, Mary E Hanson, Qian Dong, Arvind Shah and Philippe Brudi
    Citation: Lipids in Health and Disease 2010 9:127
    Content type: Research Published on:

  31. Conjugated linoleic acids (CLA) are a group of positional and geometric isomers of linoleic acid with proven beneficial influence on health. They show e.g. anticarcinogenic, antiobesity, and antiatherogenic ef...

    Authors: Agnieszka Białek, Andrzej Tokarz, Agnieszka Dudek, Weronika Kazimierska and Wojciech Bielecki
    Citation: Lipids in Health and Disease 2010 9:126
    Content type: Research Published on:

  32. Sleep deprivation has been shown to increase inflammatory markers in rat sera and peripheral blood mononuclear cells. Inflammation is a condition associated with pathologies such as obesity, cancer, and cardio...

    Authors: José C Rosa Neto, Fábio S Lira, Daniel P Venancio, Cláudio A Cunha, Lila M Oyama, Gustavo D Pimentel, Sérgio Tufik, Cláudia M Oller do Nascimento, Ronaldo VT Santos and Marco T de Mello
    Citation: Lipids in Health and Disease 2010 9:125
    Content type: Research Published on:

  33. Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme catabolism, has been reported to have potential antioxidant properties. However, the role of HO-1 on hepatocyte apoptosis remains unclear. We aim to el...

    Authors: YueMin Nan, RongQi Wang, SuXian Zhao, Fang Han, Wen Juan Wu, LingBo Kong, Na Fu, Li Kong and Jun Yu
    Citation: Lipids in Health and Disease 2010 9:124
    Content type: Research Published on:

  34. The association of methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and serum lipid profiles is still controversial in diverse ethnics. Bai Ku Yao is an isolated subgroup of the Yao minority in Ch...

    Authors: Lin Zhang, Rui-Xing Yin, Wan-Ying Liu, Lin Miao, Dong-Feng Wu, Lynn Htet Htet Aung, Xi-Jiang Hu, Xiao-Li Cao, Jin-Zhen Wu and Shang-Ling Pan
    Citation: Lipids in Health and Disease 2010 9:123
    Content type: Research Published on:

  35. The association between modulation of detailed lipoprotein profiles and cholesterol ester transfer (CET) activity by peroxisome proliferator-activated receptor (PPAR)-a agonists in patients with coronary arter...

    Authors: Tetsuro Miyazaki, Kazunori Shimada, Katsumi Miyauchi, Atsumi Kume, Kosei Tanimoto, Takashi Kiyanagi, Katsuhiko Sumiyoshi, Makoto Hiki, Hiroshi Mokuno, Shinya Okazaki, Hitoshi Sato, Takeshi Kurata and Hiroyuki Daida
    Citation: Lipids in Health and Disease 2010 9:122
    Content type: Research Published on:

  36. Intermittent hypoxia (IH), a model of sleep apnea, produces weight loss in animals. We hypothesized that changes in brown adipose tissue (BAT) function are involved in such phenomenon. We investigated the effe...

    Authors: Denis Martinez, Cintia Z Fiori, Diego Baronio, Alicia Carissimi, Renata SR Kaminski, Lenise J Kim, Darlan P Rosa and Ângelo Bos
    Citation: Lipids in Health and Disease 2010 9:121
    Content type: Research Published on:

  37. To investigate the effect of oxidized low density lipoprotein receptor-1 (LOX-1) on tubular epithelial-mesenchymal transition (TEMT) induced by oxidized low-density lipoprotein (ox-LDL) and its mechanism.

    Authors: Rui Wang, Guohua Ding, Wei Liang, Cheng Chen and Hongxia Yang
    Citation: Lipids in Health and Disease 2010 9:120
    Content type: Short paper Published on:

  38. The double-blinded placebo-controlled randomized study has been performed in 51 coronary heart disease (CHD) patients to estimate the effects of time-released garlic powder tablets Allicor on the values of 10-...

    Authors: Igor A Sobenin, Valentin V Pryanishnikov, Lyudmila M Kunnova, Yevgeny A Rabinovich, Danik M Martirosyan and Alexander N Orekhov
    Citation: Lipids in Health and Disease 2010 9:119
    Content type: Research Published on:

  40. Atherosclerosis is considered a chronic inflammatory disease in which monocytes and macrophages are critical. These cells express CD14, toll-like receptor (TLR) 2, and TLR4 on their surfaces, are activated by ...

    Authors: Luis Chávez-Sánchez, Karina Chávez-Rueda, Maria Victoria Legorreta-Haquet, Edgar Zenteno, Yadira Ledesma-Soto, Eduardo Montoya-Díaz, Emiliano Tesoro-Cruz, Alejandra Madrid-Miller and Francisco Blanco-Favela
    Citation: Lipids in Health and Disease 2010 9:117
    Content type: Research Published on:

  41. This study aimed to analyze the effects of exercise at the aerobic/anaerobic transition on the markers of non-alcoholic fatty liver disease (NAFLD), insulin sensitivity and the blood chemistry of rats kept on ...

    Authors: José D Botezelli, Rodrigo F Mora, Rodrigo A Dalia, Leandro P Moura, Lucieli T Cambri, Ana C Ghezzi, Fabrício A Voltarelli and Maria AR Mello
    Citation: Lipids in Health and Disease 2010 9:116
    Content type: Research Published on:

  42. Prevalence of dyslipidemia is high and increases even in younger people. The key aim of this study was to explore the group characteristics of patients in different durations of dyslipidemia and provide clues ...

    Authors: Yingying Liu, Puhong Zhang, Wei Wang, Huan Wang, Ling Zhang, Wei Wu and Xiuhua Guo
    Citation: Lipids in Health and Disease 2010 9:115
    Content type: Research Published on:

  43. Tree shrew and beijing duck are regarded as animal models resistant to atherosclerosis (AS). This study was carried out to discover the potential mechanism.

    Authors: Hui-rong Liu, Gang Wu, Bing Zhou and Bao-sheng Chen
    Citation: Lipids in Health and Disease 2010 9:114
    Content type: Research Published on:

  45. Nutritional factors play a major role in cancer initiation and development. Dietary polyunsaturated fatty acids (PUFAs) have the ability to induce modifications in the activity of lipoxygenase (LOX) and cycloo...

    Authors: Andrea Comba, Damian M Maestri, María A Berra, Carolina Paola Garcia, Undurti N Das, Aldo R Eynard and María E Pasqualini
    Citation: Lipids in Health and Disease 2010 9:112
    Content type: Research Published on:

  46. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) amplifies intracellular glucocorticoid action by converting inactive glucocorticoids to their active forms in vivo. Adipose-specific overexpression of...

    Authors: Sakamuri SS Vara Prasad, Shanmugam S Jeya Kumar, Putcha Uday Kumar, Syed SYH Qadri and Ayyalasomayajula Vajreswari
    Citation: Lipids in Health and Disease 2010 9:111
    Content type: Short paper Published on:

  47. Endothelial lipase (EL) is a major determinant of high-density lipoprotein-cholesterol (HDL-C) metabolism, but the association of endothelial lipase gene (LIPG) polymorphism and serum HDL-C levels is scarce and c...

    Authors: Wan-Ying Liu, Rui-Xing Yin, Lin Zhang, Xiao-Li Cao, Lin Miao, Dong-Feng Wu, Lynn Htet Htet Aung, Xi-Jiang Hu, Wei-Xiong Lin and De-Zhai Yang
    Citation: Lipids in Health and Disease 2010 9:110
    Content type: Research Published on:

  48. Cytokines (IL-6, IL-10 and TNF-α) are increased after exhaustive exercise in the rat retroperitoneal (RPAT) and mesenteric adipose tissue (MEAT) pads. On the other hand, these cytokines show decreased expressi...

    Authors: Fábio S Lira, José C Rosa, Gustavo D Pimentel, Victor AF Tarini, Ricardo M Arida, Flávio Faloppa, Eduardo S Alves, Cláudia O do Nascimento, Lila M Oyama, Marília Seelaender, Marco T de Mello and Ronaldo VT Santos
    Citation: Lipids in Health and Disease 2010 9:109
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X