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  1. NPC1L1 encodes a putative intestinal sterol transporter which is the likely target for ezetimibe, a new type of lipid-lowering medication. We previously reported rare non-synonymous mutations in NPC1L1 in an indi...

    Authors: Robert A Hegele, Justin Guy, Matthew R Ban and Jian Wang
    Citation: Lipids in Health and Disease 2005 4:16
  2. Abstract Hyperlipidemia and increased degree of oxidative stress are among the important risk factors for Atherosclerosis in renal transplant recipients (RTR). The Medical treatment of hyperlipidemia in RTR be...

    Authors: Abbas Jabbari, Hassan Argani, Amir Ghorbanihaghjo and Reza Mahdavi
    Citation: Lipids in Health and Disease 2005 4:11
  3. The requirement of cholesterol for internalization of eukaryotic pathogens like protozoa (Leishmaniasis, Malaria and Toxoplasmosis) and the exchange of cholesterol along with other metabolites during reproduction...

    Authors: Devendra Bansal, Harinderpal Singh Bhatti and Rakesh Sehgal
    Citation: Lipids in Health and Disease 2005 4:10
  4. Polyunsaturated fatty acids (PUFA) are thought to play important roles in inflammation. The n-3 series is considered as anti-inflammatory, and some studies have reported increased plasma n-3 polyunsaturated fa...

    Authors: Tiina Solakivi, Olli Jaakkola, Anne Kalela, Mari Pispa, Anne Salomäki, Terho Lehtimäki, Matti Höyhtyä, Hannu Jokela and Seppo T Nikkari
    Citation: Lipids in Health and Disease 2005 4:8
  5. Metabolic syndrome is a collection of associated conditions such as dyslipidemia, high blood pressure, impaired glucose tolerance and tendency to develop fat around the abdomen. It is now well known that indiv...

    Authors: Demosthenes B Panagiotakos and Evangelos Polychronopoulos
    Citation: Lipids in Health and Disease 2005 4:7
  6. This study tested the hypothesis that human macrophages have the ability to modify oxidation products in LDL and oxidized LDL (oxLDL) via a cellular antioxidant defence system. While many studies have focused ...

    Authors: Lillemor Mattsson Hultén, Christina Ullström, Alexandra Krettek, David van Reyk, Stefan L Marklund, Claes Dahlgren and Olov Wiklund
    Citation: Lipids in Health and Disease 2005 4:6
  7. Autotaxin (ATX, NPP-2), originally purified as a potent tumor cell motility factor, is now known to be the long-sought plasma lysophospholipase D (LPLD). The integrity of the enzymatic active site, including t...

    Authors: Timothy Clair, Eunjin Koh, Malgorzata Ptaszynska, Russell W Bandle, Lance A Liotta, Elliott Schiffmann and Mary L Stracke
    Citation: Lipids in Health and Disease 2005 4:5
  8. Protease inhibitors are known to alter the lipid profiles in subjects treated for HIV/AIDS. However, the magnitude of this effect on plasma lipoproteins and lipids has not been adequately quantified.

    Authors: Adrian R Levy, Lawrence McCandless, P Richard Harrigan, Robert S Hogg, Greg Bondy, Uchenna H Iloeje, Jayanti Mukherjee and Julio S Montaner
    Citation: Lipids in Health and Disease 2005 4:4
  9. Studies in rodents and some studies in humans have shown that conjugated linoleic acid (CLA), especially its trans-10, cis-12 isomer, reduces body fat content. However, some but not all studies in mice and humans...

    Authors: Ed Wargent, Matthew V Sennitt, Claire Stocker, Andrew E Mayes, Louise Brown, Jacqueline O'Dowd, Steven Wang, Alexandra WC Einerhand, Inge Mohede, Jonathan RS Arch and Michael A Cawthorne
    Citation: Lipids in Health and Disease 2005 4:3
  10. Transport of fatty acids within the cytosol of adipocytes and their subsequent assimilation into lipid droplets has been thoroughly investigated; however, the mechanism by which fatty acids are transported acr...

    Authors: Larissa C Wilsie, Shree Chanchani, Deepti Navaratna and Robert A Orlando
    Citation: Lipids in Health and Disease 2005 4:2
  11. Apolipoprotein A-V (Apo A-V) gene has recently been identified as a new apolipoprotein involved in triglyceride metabolism. A single nucleotide polymorphism (SNP3) located in the gene promoter (-1131) was asso...

    Authors: Raja Chaaba, Nebil Attia, Sonia Hammami, Maha Smaoui, Sylvia Mahjoub, Mohamed Hammami and Ahmed Slaheddine Masmoudi
    Citation: Lipids in Health and Disease 2005 4:1
  12. To determine the correlates of serum lipoprotein (a) (Lp(a)) in children and adolescents in the United States.

    Authors: Thomas O Obisesan, Muktar H Aliyu, Abayomi S Adediran, Vernon Bond, Celia J Maxwell and Charles N Rotimi
    Citation: Lipids in Health and Disease 2004 3:29
  13. The lipoprotein lipase (LPL) hydrolyses circulating triacylglycerol-rich lipoproteins. Thereby, LPL acts as a metabolic gate-keeper for fatty acids partitioning between adipose tissue for storage and skeletal ...

    Authors: Florence Gondret, Sanjay B Jadhao, Marie Damon, Patrick Herpin, Céline Viglietta, Louis-Marie Houdebine and Jean-François Hocquette
    Citation: Lipids in Health and Disease 2004 3:27
  14. The response of serum cholesterol to diet may be affected by the apolipoprotein E (APOE) ε2/ε3/ε4 polymorphism, which also is a significant predictor of variation in the risk of coronary heart disease (CHD) and C...

    Authors: Elisabeth Strandhagen, Henrik Zetterberg, Nibia Aires, Mona Palmér, Lars Rymo, Kaj Blennow and Dag S Thelle
    Citation: Lipids in Health and Disease 2004 3:26
  15. Conjugated fatty acid, the general term of positional and geometric isomers of polyunsaturated fatty acids with conjugated double bonds, has attracted considerable attention because of its potentially benefici...

    Authors: Keisuke Arao, Yu-Ming Wang, Nao Inoue, Junichi Hirata, Jae-Young Cha, Koji Nagao and Teruyoshi Yanagita
    Citation: Lipids in Health and Disease 2004 3:24
  16. Apolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-dens...

    Authors: Guanghua Luo, Xiaoying Zhang, Peter Nilsson-Ehle and Ning Xu
    Citation: Lipids in Health and Disease 2004 3:21
  17. One of the primary causes of otitis media (OM), an inflammation of the middle ear, is the bacterium Haemophilus influenzae (HI). OM often occurs to young children, and is mostly treated with antibiotics. Due to c...

    Authors: Jim-Wen R Liu, Steve N Anderson, Jonathan A Meulbroek, Shie-Ming Hwang, Pradip Mukerji and Yung-Sheng Huang
    Citation: Lipids in Health and Disease 2004 3:20
  18. Low levels of high density lipoprotein (HDL) cholesterol and disturbed postprandial lipemia are associated with coronary heart disease. In the present study, we evaluated the variation of triglyceride (TG) pos...

    Authors: Genovefa D Kolovou, Katherine K Anagnostopoulou, Nektarios Pilatis, Nikolaos Kafaltis, Konstandina Sorodila, Eleftherios Psarros and Dennis V Cokkinos
    Citation: Lipids in Health and Disease 2004 3:18
  19. Restriction of fat intake has been effective in improving insulin sensitivity in obese and type 2 diabetic subjects, but what effects the recommended diet (less than 30% of total calories from fat) have not be...

    Authors: Chung-Jung Wu and Zer-Ran Yu
    Citation: Lipids in Health and Disease 2004 3:17
  20. Malnutrition, anemia and increased atherosclerosis are the main causes of mortality in hemodialysis patients. Therapies designed to improve the disorders might therefore be expected to improve outcome. The eff...

    Authors: Amir Ghorbanihaghjo, Hassan Argani, Mohammad Rohbaninoubar and Nadereh Rashtchizadeh
    Citation: Lipids in Health and Disease 2004 3:16
  21. Oxidative stress has been demonstrated in malaria. The potential oxidative modification of lipoproteins derived from malaria patients was studied. These oxidized lipids may have role in pathogenesis of malaria.

    Authors: Nathawut Sibmooh, Paveena Yamanont, Srivicha Krudsood, Wattana Leowattana, Gary Brittenham, Sornchai Looareesuwan and Rachanee Udomsangpetch
    Citation: Lipids in Health and Disease 2004 3:15
  22. The theoretical benefits of using antioxidant vitamin supplements to quench oxygen free radicals appear large. High intensity aerobic-type exercise produces oxygen free radicals that can cause damage to lipid ...

    Authors: Peter E Viitala, Ian J Newhouse, Norm LaVoie and Christine Gottardo
    Citation: Lipids in Health and Disease 2004 3:14
  23. The aim of the current study was to examine the influence of socioeconomic status (SES) on physiological (lipid profile, obesity indices) and behavioral (dietary habits, physical activity) cardiovascular disea...

    Authors: Yannis Manios, Maria Dimitriou, George Moschonis, Bike Kocaoglu, Haydar Sur, Yasar Keskin and Osman Hayran
    Citation: Lipids in Health and Disease 2004 3:11
  24. The important role of APOAV gene T-1131>C variant in determination of plasma triglyceride levels has been proved on many population studies. Recently, associations between C-1131 allele and higher mother's height...

    Authors: Jaroslav A Hubacek, Zdena Skodova, Vera Adamkova, Vera Lanska, Dagmar Bobkova and Rudolf Poledne
    Citation: Lipids in Health and Disease 2004 3:10
  25. The NCEP III -ATP guidelines provide clear clinical directives for lipid management especially statins therapy in appropriate patient groups. Compliance of primary care physicians with these guidelines especia...

    Authors: Zakari Y Aliyu, Sohair B Yousif, Kate Plantholt, Hamisu M Salihu, Ayodele Erinle and Steve Plantholt
    Citation: Lipids in Health and Disease 2004 3:9
  26. The Lp(a) lipoprotein (Lp(a)) consists of the polymorphic glycoprotein apolipoprotein(a) (apo(a)), which is attached by a disulfide bond to apolipoprotein B (apoB). Apo(a), which has high homology with plasmin...

    Authors: Päivi A Teivainen, Knut A Eliassen, Edward M Rubin, Srdjan Djurovic and Kåre Berg
    Citation: Lipids in Health and Disease 2004 3:8
  27. HMG-CoA reductase inhibitors (statins) are commonly used in medicine to control blood lipid disorder. Large clinical trials have demonstrated that statins greatly reduces cardiovascular-related morbidity and m...

    Authors: Martin Noël, Claude Gagné, Jean Bergeron, Jean Jobin and Paul Poirier
    Citation: Lipids in Health and Disease 2004 3:7
  28. Atherosclerosis is the main cause of mortality and morbidity in end stage renal diseases (ESRD), especially in hemodialysis (HD) patients. In addition the classic risk factors for atherosclerosis, non classica...

    Authors: Hassan Argani, Amir Ghorbani, Nadereh Rashtchizade and Mohammad Rahbaninobar
    Citation: Lipids in Health and Disease 2004 3:6
  29. β-oxidation of long and very long chain fatty acyl-CoA derivatives occurs in peroxisomes, which are ubiquitous subcellular organelles of eukaryotic cells. This pathway releases acetyl-CoA as precursor for seve...

    Authors: Stéphane Desaint, Franck Hansmannel, Marie-Claude Clémencet, Catherine Le Jossic-Corcos, Valérie Nicolas-Frances, Norbert Latruffe and Mustapha Cherkaoui-Malki
    Citation: Lipids in Health and Disease 2004 3:4
  30. Beta-thalassaemia major (b-TM) has been defined as a combination of chronic hemolytic anemia, iron storage disease and myocarditis, and it has been associated with premature death especially due to heart failu...

    Authors: Christina Chrysohoou, Demosthenes B Panagiotakos, Christos Pitsavos, Konstantina Kosma, John Barbetseas, Markisia Karagiorga, Ioannis Ladis and Christodoulos Stefanadis
    Citation: Lipids in Health and Disease 2004 3:3
  31. There has been renewed interest in mushroom medicinal properties. We studied cholesterol lowering properties of Ganoderma lucidum (Gl), a renowned medicinal species.

    Authors: A Berger, D Rein, E Kratky, I Monnard, H Hajjaj, I Meirim, C Piguet-Welsch, J Hauser, K Mace and P Niederberger
    Citation: Lipids in Health and Disease 2004 3:2
  32. Previous studies have shown that the functional capacity of T cells may be modulated by the composition of fatty acids within, and the release of fatty acids from membrane phospholipids, particulary containing...

    Authors: Michiyo Tomita, Rodney C Baker, Soichiro Ando and Thomas J Santoro
    Citation: Lipids in Health and Disease 2004 3:1
  33. Triglyceride concentrations are raised in pregnancy and are considered a key fetal fuel. Several gene variants are known to alter triglyceride concentrations, including those in the Apolipoprotein E (ApoE), Lipop...

    Authors: Kirsten J Ward, Beverley Shields, Beatrice Knight, Maurice B Salzmann, Andrew T Hattersley and Timothy M Frayling
    Citation: Lipids in Health and Disease 2003 2:9
  34. Offspring of at least 1 parent with type 2 diabetes are more resistant to the insulin action, exhibit higher incidence of dyslipidemia and are more prone to cardiovascular diseases. The association between Lp(...

    Authors: Agathoklis Psyrogiannis, Ioannis Habeos and Venetsana Kyriazopoulou
    Citation: Lipids in Health and Disease 2003 2:8
  35. Hyperhomocysteinemia and lipid abnormalities are commonly found in patients with chronic renal failure; both are recognized as risk factors for atherosclerosis. The homocysteine-lowering effect of pyridoxine i...

    Authors: Nelva T de Gómez Dumm, Ana M Giammona and Luis A Touceda
    Citation: Lipids in Health and Disease 2003 2:7
  36. In spite of the considerable amount of experimental, clinical and epidemiological research about the consumption of red meat, total fats, saturated/unsaturated fatty acids and cholesterol with regard to the ri...

    Authors: Aldo R Eynard and Cristina B Lopez
    Citation: Lipids in Health and Disease 2003 2:6

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