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  1. Soluble low-density lipoprotein receptor (sLDLR) is the circulating ectodomain of transmembrane LDLR. Its blood level strongly correlates with that of triglycerides (TG). This correlation has eluded satisfacto...

    Authors: Majambu Mbikay, Janice Mayne and Michel Chrétien

    Citation: Lipids in Health and Disease 2020 19:17

    Content type: Hypothesis

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  2. We aimed to develop the age- and sex-specific reference values for lipid profile of Iranian pediatric population.

    Authors: Fatemeh Azizi-Soleiman, Maliheh Khoramdad, Ramin Heshmat, Hanieh-Sadat Ejtahed, Mohammad Esmaeil Motlagh, Seyede Shahrbanoo Daniali, Mostafa Qorbani and Roya Kelishadi

    Citation: Lipids in Health and Disease 2020 19:16

    Content type: Research

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  3. n-3 polyunsaturated fatty acids (n-3 PUFAs), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are thought to exert protective effects in cardiovascular diseases. In addition, n-3 PUFAs hav...

    Authors: Keiichi Oono, Kazuo Ohtake, Chie Watanabe, Sachiko Shiba, Takashi Sekiya and Keizo Kasono

    Citation: Lipids in Health and Disease 2020 19:15

    Content type: Research

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  4. Altered lipid metabolism is an important characteristic of neoplastic cells, with androgens and growth factors being major regulatory agents of the lipid metabolism process. We investigated the effect of physi...

    Authors: Giovana Rampazzo Teixeira, Leonardo Oliveira Mendes, Allice Santos Cruz Veras, Hayley Hope Allyssa Thorpe, Wagner José Fávaro, Luiz Gustavo de Almeida Chuffa, Patrícia Fernanda Felipe Pinheiro and Francisco Eduardo Martinez

    Citation: Lipids in Health and Disease 2020 19:14

    Content type: Research

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  5. Han and Uygur are the two main nationalities living in Xinjiang, China. There are significant differences in the incidence of metabolic diseases for two nationalities, but the specific reasons are not clear. O...

    Authors: Yinghua Ma, Tongtong Qiu, Jiaojiao Zhu, Jingzhou Wang, Xue Li, Yuchun Deng, Xueting Zhang, Jiale Feng, Keru Chen, Cuizhe Wang, Jianxin Xie and Jun Zhang

    Citation: Lipids in Health and Disease 2020 19:13

    Content type: Research

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  6. Dyslipidemia is a multifactorial disorder, which arises from complex interactions among genetic and environmental risk factors. Previous studies have established the deteriorating effect of aging on lipid prof...

    Authors: So Mi Jemma Cho, Ho Jae Lee, Jee Seon Shim, Bo Mi Song and Hyeon Chang Kim

    Citation: Lipids in Health and Disease 2020 19:12

    Content type: Research

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  7. Previous evidence suggests that plasma phospholipid fatty acids (PPFAs) and HOMA insulin resistance (HOMA-IR) are independently related to leukocyte telomere length (LTL). However, there is limited evidence of...

    Authors: Yi Zhao, Binxia Wang, Guoqi Wang, Lixia Huang, Ting Yin, Xiaoxia Li, Xiuying Liu, Qingan Wang, Jinyun Jing, Jianjun Yang and Yuhong Zhang

    Citation: Lipids in Health and Disease 2020 19:11

    Content type: Research

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  8. Ω-3 fatty acids perform several therapeutic functions in the body, however, their applications are limited due to the inferior oxidative stability. To improve the oxidative stability and release properties of ...

    Authors: Rahman Ullah, Muhammad Nadeem, Muhammad Imran, Muhammad Kamran Khan, Zarina Mushtaq, Muhammad Asif and Ahmad Din

    Citation: Lipids in Health and Disease 2020 19:10

    Content type: Research

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  9. Previously, we found a significant relationship in a rat study between energy intake and bile acid (BA) metabolism especially 12α-hydroxylated (12αOH) BAs. The present study was designed to reveal relationship...

    Authors: Reika Yoshitsugu, Keidai Kikuchi, Shota Hori, Hitoshi Iwaya, Masahito Hagio, Hidehisa Shimizu, Tohru Hira and Satoshi Ishizuka

    Citation: Lipids in Health and Disease 2020 19:9

    Content type: Research

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  10. It is believed that deposition of amyloid beta (Aβ) in the brain is the central pathological changes of Alzheimer’s disease (AD), which triggers a series of pathological processes. However, the relationship be...

    Authors: Ningwei Hu, Ling Gao, Yu Jiang, Shan Wei, Suhang Shang, Chen Chen, Liangjun Dang, Jin Wang, Kang Huo, Meiying Deng, Jingyi Wang and Qiumin Qu

    Citation: Lipids in Health and Disease 2020 19:8

    Content type: Research

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  11. Atherosclerotic cardiovascular (CV) events commonly occur in individuals with a low CV risk burden. This study evaluated the ability of the triglyceride glucose (TyG) index to predict subclinical coronary arte...

    Authors: Gyung-Min Park, Young-Rak Cho, Ki-Bum Won, Yu Jin Yang, Sangwoo Park, Soe Hee Ann, Yong-Giun Kim, Eun Ji Park, Shin-Jae Kim, Sang-Gon Lee, Dong Hyun Yang, Joon-Won Kang, Tae-Hwan Lim, Hong-Kyu Kim, Jaewon Choe, Seung-Whan Lee…

    Citation: Lipids in Health and Disease 2020 19:7

    Content type: Research

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  12. The HMG-CoA reductase is key enzyme of cholesterol biosynthesis which potentially contributes in management of hypercholesterolemia. The present study was designed to assess the inhibitory effect of phytoconst...

    Authors: Heera Ram, Noopur Jaipal, Jaykaran Charan, Priya Kashyap, Suresh Kumar, Rashmi Tripathi, Bhim Pratap Singh, Chandra Nayaka Siddaiah, Abeer Hashem, Baby Tabassum and Elsayed Fathi Abd_Allah

    Citation: Lipids in Health and Disease 2020 19:6

    Content type: Research

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  13. Real-world evidence of low-density lipoprotein cholesterol (LDL-C) goal attainment rates for Asian patients is deficient. The objective of this study was to assess the status of dyslipidemia management, especi...

    Authors: Ye Seul Yang, Bo Ram Yang, Mi-Sook Kim, Yunji Hwang and Sung Hee Choi

    Citation: Lipids in Health and Disease 2020 19:5

    Content type: Research

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  14. Menopause predisposes individuals to affective disorders, such as depression, which is tightly related to neuroinflammation. While the neuroinflammatory condition has been demonstrated in ovariectomized (OVX) ...

    Authors: Bin Wu, Qingen Song, Yongkang Zhang, Changshui Wang, Mengqi Yang, Jun Zhang, Wenxiu Han and Pei Jiang

    Citation: Lipids in Health and Disease 2020 19:4

    Content type: Research

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  15. Use of ezetimibe on top of statin therapy has been shown to be effective to reduce LDL cholesterol level in hypercholesterolemic patients. However, little is known regarding the individual variety of the effec...

    Authors: Hayato Tada, Hirofumi Okada, Akihiro Nomura, Masayuki Takamura and Masa-aki Kawashiri

    Citation: Lipids in Health and Disease 2020 19:3

    Content type: Research

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  16. Acute pancreatitis is a pregnancy complication potentially lethal for both the mother and fetus, occurring most frequently in the third trimester or early postpartum. Hypertriglyceridemia may be the cause of i...

    Authors: Gheorghe Cruciat, Georgiana Nemeti, Iulian Goidescu, Stefan Anitan and Andreea Florian

    Citation: Lipids in Health and Disease 2020 19:2

    Content type: Review

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  17. The aim of this study was to compare and summarize the lipid-altering effects of combination therapy with ezetimibe and statins (E/S) and a double dose of statin (D/S) monotherapy on patients with hypercholest...

    Authors: Min Yu, Chunshui Liang, Qianran Kong, Yihan Wang and Minmin Li

    Citation: Lipids in Health and Disease 2020 19:1

    Content type: Research

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  18. Cerebrotendinous xanthomatosis (CTX) and Lathosterolosis represent two treatable inherited disorders of cholesterol metabolism that are characterized by the accumulation of cholestanol and lathosterol, respect...

    Authors: Monica Gelzo, Maria Donata Di Taranto, Concetta Sica, Antonio Boscia, Francesco Papagni, Giuliana Fortunato, Gaetano Corso and Antonio Dello Russo

    Citation: Lipids in Health and Disease 2019 18:235

    Content type: Research

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  19. Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide, although its pathogenesis remains to be elucidated. A recent study revealed that hepatic Niemann-Pick C1-Like 1 (NP...

    Authors: Yu Toyoda, Tappei Takada, Yoshihide Yamanashi and Hiroshi Suzuki

    Citation: Lipids in Health and Disease 2019 18:234

    Content type: Research

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  20. Previous genome-wide association studies have found two single nucleotide polymorphisms (SNP) rs7692387 and rs1842896 located on or near the GUCY1A3 gene were associated with coronary artery disease (CAD). GUCY1A...

    Authors: Jian-li Li, Liu-yu Liu, Dong-dong Jiang, Yi-ying Jiang, Guo-qiu Zhou, Dong-can Mo and Man Luo

    Citation: Lipids in Health and Disease 2019 18:233

    Content type: Research

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  21. Chanarin Dorfman Syndrome (CDS) is a rare autosomal recessive disorder characterized by the multisytemic accumulation of neutral lipids inside the cytoplasmic lipid droplets. This condition is caused by mutati...

    Authors: Ali Haydar Eskiocak, Sara Missaglia, Laura Moro, Murat Durdu and Daniela Tavian

    Citation: Lipids in Health and Disease 2019 18:232

    Content type: Short report

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  22. Considering the crucial role of low-density lipoprotein-cholesterol (LDL-C) concentration in determining cardiovascular risk, the accuracy of LDL-C estimation is essential. To date, various types of formulae h...

    Authors: Azam Karkhaneh, Molood Bagherieh, Solmaz Sadeghi and Asma Kheirollahi

    Citation: Lipids in Health and Disease 2019 18:231

    Content type: Research

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  23. Adipogenesis is the process of adipocytes formation from unspecialized progenitor cells called mesenchymal stromal cells. Numerous mechanisms including epigenetic regulation modulate the correct progress of th...

    Authors: Malgorzata Malodobra-Mazur, Aneta Cierzniak and Tadeusz Dobosz

    Citation: Lipids in Health and Disease 2019 18:230

    Content type: Research

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  24. Hypertension is a highly prevalent disease and the leading cause of chronic kidney disease (CKD). Metabolic syndrome could also be the risk factor for CKD. We sought to study the association between metabolic ...

    Authors: Kun Xie, Liwen Bao, Xiaofei Jiang, Zi Ye, Jianping Bing, Yugang Dong, Danchen Gao, Xiaoping Ji, Tingbo Jiang, Jiehua Li, Yan Li, Suxin Luo, Wei Mao, Daoquan Peng, Peng Qu, Shangming Song…

    Citation: Lipids in Health and Disease 2019 18:229

    Content type: Research

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  25. Influences of atorvastatin on atherosclerosis and glycemic metabolism may be related to its potential impact on circulating adiponectin, an adipocyte that exerts anti-inflammatory, ant-atherosclerotic, and ant...

    Authors: Xiaoyu Liu, Wei Zhang, Ming Zhao, Guowei Jia and Rongguo Sun

    Citation: Lipids in Health and Disease 2019 18:228

    Content type: Review

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  26. Conflicting results on the prognostic value of blood adiponectin level in patients with coronary artery disease (CAD) have been reported. This meta-analysis aimed to investigate the prognostic value of elevate...

    Authors: Lili Yang, Bin Li, Yuan Zhao and Zhengyi Zhang

    Citation: Lipids in Health and Disease 2019 18:227

    Content type: Review

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  27. Endothelial lipase (EL) plays an important role in lipoprotein metabolism and atherosclerosis. To study the functional roles of EL, we recently generated transgenic (Tg) rabbits and reported that increased hep...

    Authors: Chuan Wang, Manabu Niimi, Shuji Kitajima, Fumikazu Matsuhisa, Haizhao Yan, Sijun Dong, Jingyan Liang and Jianglin Fan

    Citation: Lipids in Health and Disease 2019 18:226

    Content type: Research

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  28. Hypocholesterolemia is the most frequently encountered lipid abnormality in sickle cell disease (SCD). We enrolled pediatric patients to determine the relationships between lipid profile and parameters of hemo...

    Authors: Ahmet Yalcinkaya, Selma Unal and Yesim Oztas

    Citation: Lipids in Health and Disease 2019 18:225

    Content type: Research

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  29. APOC3 is important in lipid transport and metabolism with limited studies reporting genetic sequence variations in specific ethnic groups. The present study aimed to analyze the full APOC3 sequence among Kuwaiti ...

    Authors: Zainab H. Malalla, Ahmad E. Al-Serri, Huda M. AlAskar, Wafaa Y. Al-Kandari and Suzanne A. Al-Bustan

    Citation: Lipids in Health and Disease 2019 18:224

    Content type: Research

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  30. Obesity is the most common nutritional disorder worldwide and is associated with dyslipidemia and atherosclerotic cardiovascular disease. The hallmark of dyslipidemia in obesity is low high density lipoprotein...

    Authors: Tianhua Zhang, Jin Chen, Xiaoyu Tang, Qin Luo, Danyan Xu and Bilian Yu

    Citation: Lipids in Health and Disease 2019 18:223

    Content type: Review

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  31. Lipids and adipokines including leptin, resistin and visfatin play various roles in the pathophysiology of Gestational Diabetes Mellitus (GDM). This study was aimed at determining whether serum leptin, resisti...

    Authors: Ahmed Tijani Bawah, Mohammed Mustapha Seini, Albert Abaka-Yawason, Huseini Alidu and Salifu Nanga

    Citation: Lipids in Health and Disease 2019 18:221

    Content type: Research

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  32. Apolipoprotein C3 (apoC3) and apolipoprotein A5 (apoA5), encoded by APOA1/C3/A4/A5 gene cluster, are two critical regulators of plasma triglyceride (TG) metabolism. Deficiency of apoC3 or apoA5 led to significant...

    Authors: Wen Dai, Ziyu Zhang, Chun Yao and Shuiping Zhao

    Citation: Lipids in Health and Disease 2019 18:220

    Content type: Review

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  33. High-density lipoprotein cholesterol (HDL-C) is considered as a protective marker of coronary atherosclerotic disease (CAD). It is still not clear if HDL-C is associated with left ventricular (LV) diastolic fu...

    Authors: Lufan Sun, Xiaorui Liu, Wenna Li and Dalin Jia

    Citation: Lipids in Health and Disease 2019 18:219

    Content type: Research

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  34. The cholesterol gallstones diseases (CGD) is highly correlated with metabolic syndrome and type 2 diabetes. The present study aimed to investigate preventive effects of pioglitazone (PIO), an antidiabetic drug...

    Authors: Tao Han, Yangge Lv, Shijia Wang, Tao Hu, Hao Hong and Zan Fu

    Citation: Lipids in Health and Disease 2019 18:218

    Content type: Research

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  35. Coronary artery disease (CAD) is the leading cause of mortality and morbidity worldwide. Previous studies have shown that complement component 3 (C3) is associated with atherosclerosis and cardiovascular risk ...

    Authors: Gaojun Cai, Li Li, Yifei Chen, Haomin Huang, Lei Yu and Lianhong Xu

    Citation: Lipids in Health and Disease 2019 18:217

    Content type: Research

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  36. There is no randomized clinical trials with recurrence of atherosclerotic cardiovascular disease (ASCVD) as a major outcome with rosuvastatin. In order to analyze potential differences in the clinical response...

    Authors: Sofía Perez-Calahorra, Martin Laclaustra, Victoria Marco-Benedi, Xavier Pinto, Rosa M. Sanchez-Hernandez, Núria Plana, Emilio Ortega, Francisco Fuentes and Fernando Civeira

    Citation: Lipids in Health and Disease 2019 18:216

    Content type: Short report

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  37. Macrophage are specialized cells that contributes to the removal of detrimental contents via phagocytosis. Lipid accumulation in macrophages, whether from phagocytosis of dying cells or from circulating oxidiz...

    Authors: Priscila Calle, Angeles Muñoz, Anna Sola and Georgina Hotter

    Citation: Lipids in Health and Disease 2019 18:215

    Content type: Research

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  38. To study whether minimal doses of arachidonic acid (AA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and lipoxin A4 (LXA4) and brain-derived neurotrophic factor (BDNF), when used in combination ...

    Authors: Siresha Bathina and Undurti N. Das

    Citation: Lipids in Health and Disease 2019 18:214

    Content type: Research

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  39. In developing and developed countries, several versions of safe and shelf-stable Ultra High Temperature, UHT-treated products are manufactured. Terminologies and formulations of UHT-treated tea whitener, milk ...

    Authors: Muhammad Ajmal, Muhammad Nadeem, Muhammad Imran, Zarina Mushtaq, Muhammad Haseeb Ahmad, Muhammad Tayyab, Muhammad Kamran Khan and Nabila Gulzar

    Citation: Lipids in Health and Disease 2019 18:213

    Content type: Research

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  40. Insulin resistance (IR) and lipid peroxidation are accepted as ‘two-hit’ hypothesis of Non-alcoholic fatty liver disease (NAFLD). However, there are few published research on identifying genes which connect li...

    Authors: Ting Li, Hua Yan, Yan Geng, Haitao Shi, Hong Li, Shenhao Wang, Yatao Wang, Jingyuan Xu, Gang Zhao and Xiaolan Lu

    Citation: Lipids in Health and Disease 2019 18:211

    Content type: Research

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  41. It has been confirmed that the triglyceride to high-density lipoprotein cholesterol ratio (THR) is associated with insulin resistance and metabolic syndrome. However, to the best of our knowledge, only a few s...

    Authors: Xin-Ya Dai, Ying-Ying Zheng, Jun-Nan Tang, Xu-Ming Yang, Qian-Qian Guo, Jian-Chao Zhang, Meng-Die Cheng, Feng-Hua Song, Zhi-Yu Liu, Kai Wang, Li-Zhu Jiang, Lei Fan, Xiao-Ting Yue, Yan Bai, Zeng-Lei Zhang, Ru-Jie Zheng…

    Citation: Lipids in Health and Disease 2019 18:210

    Content type: Research

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  42. Consumption of a Western-styled diet enriched in saturated fatty acids (SFA) relative to polyunsaturated fatty acids is positively associated with risk for Alzheimer’s disease. Whilst potential causal mechanis...

    Authors: Susan Galloway, Ryusuke Takechi, Michael Nesbit, Menuka M. Pallebage-Gamarallage, Virginie Lam and John C. L. Mamo

    Citation: Lipids in Health and Disease 2019 18:209

    Content type: Research

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  43. MicroRNAs are short non-coding RNAs that regulate gene expression. The aim of this study was to gain an understanding of the possible role of the miR-106b~ 25 microRNA cluster in regulating atherosclerosis in ...

    Authors: Jonathan Semo, Gil Chernin, Michael Jonas, Sara Shimoni and Jacob George

    Citation: Lipids in Health and Disease 2019 18:208

    Content type: Research

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  44. Endoplasmic reticulum (ER) stress and mitochondrial function affected intramuscular fat accumulation. However, there is no clear evident on the effect of the regulation of ER stress and mitochondrial function ...

    Authors: Xi Cao, Xin-Meng Lu, Xiu Tuo, Jing-Yi Liu, Yi-Chen Zhang, Li-Ni Song, Zhi-Qiang Cheng, Jin-Kui Yang and Zhong Xin

    Citation: Lipids in Health and Disease 2019 18:207

    Content type: Research

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  45. Postprandial high triglyceride (HTG), marking elevated level of remnant cholesterol (RC), is an independent risk factor of coronary heart disease (CHD). The postprandial cut-off points for HTG and high RC (HRC...

    Authors: Jin Xu, Yan-Qiao Chen, Shui-Ping Zhao and Ling Liu

    Citation: Lipids in Health and Disease 2019 18:206

    Content type: Research

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  46. Resistant starch (RS) is a starch that can be fermented by the microbial flora within gut lumen. Insulin resistance (IR) is a pathophysiological condition related to diabetes and obesity. RS could reduce blood...

    Authors: Chenlin Gao, Mingyue Rao, Wei Huang, Qin Wan, Pijun Yan, Yang Long, Man Guo, Youhua Xu and Yong Xu

    Citation: Lipids in Health and Disease 2019 18:205

    Content type: Research

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  47. A healthy gastric mucosal epithelium exhibits tumor-suppressive properties. Gastric epithelial cell dysfunction contributes to gastric cancer development. Oxysterols provided from food or cholesterol oxidation...

    Authors: Wenting Hong, Fenghua Guo, Mingjie Yang, Dongke Xu, Ziyan Zhuang, Baolin Niu, Qianming Bai and Xiaobo Li

    Citation: Lipids in Health and Disease 2019 18:203

    Content type: Research

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