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  1. Content type: Research

    Polymorphisms have been identified to predispose to NAFLD. Here, we accessed the seven polymorphisms of rs1260326, rs780094 in GCKR, rs2954021 near TRIB1, rs2228603 in NCAN, rs58542926 in TM6SF2, rs12137855 ne...

    Authors: Wen Cai, Di-hua Weng, Ping Yan, Yu-ting Lin, Zheng-hui Dong, Mailamuguli and Hua Yao

    Citation: Lipids in Health and Disease 2019 18:14

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  2. Content type: Research

    Diabetes is often accompanied by dyslipidemia. Lipid control is very important in the management of diabetes. There are limited real world data on the lipid control in diabetic inpatients in southwest China.

    Authors: Qingtao Hou, Chuan Yu, Sheyu Li, Yun Li, Rui Zhang, Tao Zheng, Yi Ma, Miye Wang, Na Su, Ting Wu, Zhiwen Liu, Xia Sheng, Nan Li, Guanjian Liu, Yong Huang, Ting Xu…

    Citation: Lipids in Health and Disease 2019 18:13

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  3. Content type: Research

    Bioactive components of Ganoderma lucidum has recently gained intense research attention due to their acclaimed nutritional and medicinal properties. Thus, the terpenoid extract from the fruit bodies of G. lucidu...

    Authors: Olarewaju M. Oluba

    Citation: Lipids in Health and Disease 2019 18:12

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  4. Content type: Research

    Maonan nationality is a relatively conservative and isolated minority in the Southwest of China. Little is known about the association of endothelial lipase gene (LIPG) single nucleotide polymorphisms (SNPs) and ...

    Authors: Shuo Yang, Rui-Xing Yin, Liu Miao, Yong-Gang Zhou, Jie Wu and Qing-Hui Zhang

    Citation: Lipids in Health and Disease 2019 18:10

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  5. Content type: Research

    Studies have shown that non-traditional lipid profiles have a better association with stroke than traditional blood lipids in clinical applications, other studies have drawn different conclusions.

    Authors: Jia Zheng, Zhaoqing Sun, Xingang Zhang, Zhao Li, Xiaofan Guo, Yanxia Xie, Yingxian Sun and Liqiang Zheng

    Citation: Lipids in Health and Disease 2019 18:9

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  6. Content type: Research

    Obesity plays crucial roles in the pathogenesis of metabolic diseases such as hyperlipidemia, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes (T2D). The underlying mechanisms linking obesity to m...

    Authors: Junlong Wang, Linqiang Zhang, Ruyue Xiao, Yunhai Li, Shasha Liao, Zhiguo Zhang, Wenhui Yang and Bin Liang

    Citation: Lipids in Health and Disease 2019 18:8

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  7. Content type: Short report

    Lipids are implicated in the pathogenesis of age-related macular degeneration (AMD). The relationship between systemic lipids and AMD has not been well characterized. The objective was to investigate the relat...

    Authors: Richard D. Semba, Ruin Moaddel, Mary Frances Cotch, Fridbert Jonasson, Gudny Eiriksdottir, Tamara B. Harris, Lenore J. Launer, Kai Sun, Ronald Klein, Debra A. Schaumberg, Pálmi Jónsson, Vilmundur Gudnason and Luigi Ferrucci

    Citation: Lipids in Health and Disease 2019 18:7

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  8. Content type: Research

    To emphasize the mechanism of concurrent exercise effect on lipid disorders in insulin resistance (IR) and nonalcoholic fatty liver disease (NAFLD).

    Authors: Fan Zheng and Ying Cai

    Citation: Lipids in Health and Disease 2019 18:6

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  9. Content type: Research

    Coronary artery disease (CAD) is a multi-factor disease. Complement component 3 (C3) plays an important role in the development of CAD. The present study investigated the association between DNA methylation st...

    Authors: Gaojun Cai, Zhiying Huang, Lei Yu and Li Li

    Citation: Lipids in Health and Disease 2019 18:5

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  10. Content type: Research

    Serum lipids [total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG)] are risk factors for stroke, but the relationships between...

    Authors: Beiyu Zhao, Suhang Shang, Pei Li, Chen Chen, Liangjun Dang, Yu Jiang, Jin Wang, Kang Huo, Meiying Deng, Jingyi Wang and Qiumin Qu

    Citation: Lipids in Health and Disease 2019 18:4

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  11. Content type: Research

    The loss of muscle mass and concomitantly strength, poses a serious risk to the elderly and to astronauts. Dietary cholesterol (CL), in conjunction with resistance training (RT), has been strongly associated w...

    Authors: Teak V. Lee, Chang Woock Lee, Vincent C. W. Chen, Steve Bui, James D. Fluckey and Steven E. Riechman

    Citation: Lipids in Health and Disease 2019 18:3

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  12. Content type: Research

    ATP-binding cassette (ABC) transporters are involved in a huge range of physiological processes. Mutations in the ABCC6 gene cause pseudoxanthoma elasticum, a metabolic disease with progressive soft tissue calcif...

    Authors: Bettina Ibold, Isabel Faust, Janina Tiemann, Theo G. M. F. Gorgels, Arthur A. B. Bergen, Cornelius Knabbe and Doris Hendig

    Citation: Lipids in Health and Disease 2019 18:2

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  13. Content type: Research

    Excess energy intake contributes to metabolic disorders. However, the relationship between excess sugar and fat in their contributions to metabolic abnormalities remains to be further elucidated. Here we condu...

    Authors: Ke-Wei Wang, Bai-Quan Xiao, Bi-Hai Li, Yi-Yan Liu, Zhi-Yuan Wei, Jun-Hua Rao and Jian-Huan Chen

    Citation: Lipids in Health and Disease 2019 18:1

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  14. Content type: Research

    Excessive lipid depositing in liver cells could induce pathophysiological development of liver. Our study aimed to assess whether non-HDL cholesterol to HDL-cholesterol ratio (NonHDLc/HDLc) is an independent r...

    Authors: Tianhui An, Yi Song, Yi Yang, Mengyuan Guo, Hui Liu, Kun Liu and Zhaohui Wang

    Citation: Lipids in Health and Disease 2018 17:296

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  15. Content type: Short report

    Postprandial non-esterified fatty acid (NEFA) and triglyceride (TG) responses are increased in subjects with type 2 diabetes mellitus (T2DM) and may impair insulin action and increase risk of cardiovascular di...

    Authors: Amirsalar Samkani, Mads J. Skytte, Christian Anholm, Arne Astrup, Carolyn F. Deacon, Jens J. Holst, Sten Madsbad, Ray Boston, Thure Krarup and Steen B. Haugaard

    Citation: Lipids in Health and Disease 2018 17:295

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  16. Content type: Research

    Recent research had shown blood glucose was not the only cause of large for gestational age infant (LGA), the contributions of other fuels such as lipids also play an important role in fetal development. Howev...

    Authors: Ning Liang, Haiyan Zhu, Xueping Cai, Zhiyin Le, Hongliang Wang, Dian He, Rong Xiao and Huanling Yu

    Citation: Lipids in Health and Disease 2018 17:294

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  17. Content type: Research

    Inflammation may be a key pathophysiological mechanism in diabetic nephropathy (DN). Intercellular adhesion molecule 1 (ICAM1) is an acute phase marker of inflammation. ICAM1 rs5498 has been reported to be ass...

    Authors: Liya Liu, Dongling He, Ling Fang and Xiaojie Yan

    Citation: Lipids in Health and Disease 2018 17:293

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  18. Content type: Research

    The hepatokine fetuin-A is linked to obesity and type 2 diabetes, but its presence and expression in adipose tissue remain unclear. In this study, we aimed to assess the circulating levels of fetuin-A and its ...

    Authors: Abdelkrim Khadir, Sina Kavalakatt, Dhanya Madhu, Maha Hammad, Sriraman Devarajan, Jaakko Tuomilehto and Ali Tiss

    Citation: Lipids in Health and Disease 2018 17:291

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  19. Content type: Research

    Long-term statin therapy has been shown to protect against several cancers, including esophageal cancer (EC). While the mechanisms underlying this effect are not clear. We investigated the effect of hydrophobi...

    Authors: Yan Chen, Li-Bin Li, Jun Zhang, Du-Peng Tang, Jing-Jing Wei and Ze-Hao Zhuang

    Citation: Lipids in Health and Disease 2018 17:290

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  20. Content type: Research

    The present study evaluated the predictive ability of five known “best” obesity and lipid-related parameters, including body mass index (BMI), waist-to-height ratio (WHtR), triglyceride-to-high-density-lipopro...

    Authors: Zhan Gu, Ping Zhu, Qiao Wang, Huayu He, Jingjuan Xu, Li Zhang, Dong Li, Jianying Wang, Xiaojuan Hu, Guang Ji, Lei Zhang and Baocheng Liu

    Citation: Lipids in Health and Disease 2018 17:289

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  21. Content type: Research

    Hyperuricemia is related to obesity and fat accumulation. This study aimed to observe the effects of laparoscopic sleeve gastrectomy (LSG) on serum uric acid (sUA) level and body fat distribution in obese pati...

    Authors: Xuane Zhang, Cuiling Zhu, Jingyang Gao, Fangyun Mei, Jiajing Yin, Le Bu, Xiaoyun Cheng, Chunjun Sheng and Shen Qu

    Citation: Lipids in Health and Disease 2018 17:288

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  22. Content type: Research

    Krill powder is rich in bioactive ingredients such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), phospholipids, protein and astaxanthin. Containing dominantly EPA, it is considered to be effectiv...

    Authors: Essi S. Sarkkinen, Markku J. Savolainen, Jyrki Taurio, Tuuli Marvola and Inge Bruheim

    Citation: Lipids in Health and Disease 2018 17:287

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  23. Content type: Research

    Recently, trimethylamine-N-oxide (TMAO) plasma levels have been proved to be associated with atherosclerosis development. Among the targets aimed to ameliorating atherosclerotic lesions, inducing bile acid syn...

    Authors: Lin Ding, Mengru Chang, Ying Guo, Lingyu Zhang, Changhu Xue, Teruyoshi Yanagita, Tiantian Zhang and Yuming Wang

    Citation: Lipids in Health and Disease 2018 17:286

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  24. Content type: Research

    The focus of studies on high-density lipoproteins (HDL) has shifted from HDL-cholesterol (HDL-C) to HDL function. We recently demonstrated that low USF1 expression in mice and humans associates with high plasma H...

    Authors: Maija Ruuth, Jarkko Soronen, Essi Kaiharju, Krista Merikanto, Julia Perttilä, Jari Metso, Miriam Lee-Rueckert, Marja-Riitta Taskinen, Petri T. Kovanen, Katariina Öörni, Vesa M. Olkkonen, Matti S. Jauhiainen and Pirkka-Pekka Laurila

    Citation: Lipids in Health and Disease 2018 17:285

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  25. Content type: Research

    The atherogenic index of plasma showed to be related with some chronic disease like cardiovascular diseases and atherosclerosis. Body mass index which was commonly used in clinical practice is not an accurate ...

    Authors: Qian WANG, Dongmei Zheng, Jia Liu, Li FANG and Qiu Li

    Citation: Lipids in Health and Disease 2018 17:284

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  26. Content type: Research

    Diabetes mellitus is a non-infectious disease that has a high prevalence worldwide. Altered level of many haematological parameters have been observed in patients with diabetes. The levels of lipids are also a...

    Authors: Samuel Antwi-Baffour, Ransford Kyeremeh, Samuel Owusu Boateng, Lawrence Annison and Mahmood Abdulai Seidu

    Citation: Lipids in Health and Disease 2018 17:283

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  27. Content type: Research

    Designer eggs (DEs) have gained positive importance in maintaining cholesterol level, triglyceride profile and protection towards cardiovascular diseases due to the presence of essential fatty acids (EFAs) suc...

    Authors: Amna Javed, Muhammad Imran, Nazir Ahmad and Abdullah Ijaz Hussain

    Citation: Lipids in Health and Disease 2018 17:282

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  28. Content type: Research

    Several meta-analyses have demonstrated that the rs662 polymorphism in Paraoxonase 1 gene (PON1) gene is associated with coronary heart disease (CHD). However, it is still uncertain whether this polymorphism is a...

    Authors: Zhi Luo, Lijun Pu, Irfan Muhammad, Yun Chen and Xiaoqian Sun

    Citation: Lipids in Health and Disease 2018 17:281

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  29. Content type: Research

    Extracts from plants, rich in antioxidants may be used as active ingredients of many preparations, mainly due to their antioxidant, regenerative and anti-aging properties. The work involved a comprehensive eva...

    Authors: Zofia Nizioł-Łukaszewska, Dominika Furman-Toczek and Martyna Zagórska-Dziok

    Citation: Lipids in Health and Disease 2018 17:280

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  30. Content type: Research

    Hyperlipidemia is a well-established risk factor for cardiac damage, which can lead to cardiovascular diseases. Many studies have shown that Coenzyme Q10(CoQ10) protects against cardiac damage in vivo. The aim of...

    Authors: Xiaoqing Zhang, Hongyang Liu, Yuhua Hao, Lulu Xu, Tiemei Zhang, Yingshu Liu, Lipeng Guo, Liyue Zhu and Zuowei Pei

    Citation: Lipids in Health and Disease 2018 17:279

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  31. Content type: Research

    High blood lipoprotein concentrations are one of the major risk factors for cardiovascular diseases. Drug therapy is the base of treatment; statins in particular. Both brand-name and generic presentations are ...

    Authors: A. Sicras-Mainar, L. Sánchez-Álvarez, R. Navarro-Artieda and J. Darbà

    Citation: Lipids in Health and Disease 2018 17:277

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  32. Content type: Research

    An increasing number of studies have shown that obesity is the key etiological agent of cardiovascular diseases, nonalcoholic fatty liver disease, type 2 diabetes and several kinds of cancer and that gut micro...

    Authors: Yanan An, Yan Li, Xueyan Wang, Zhaobin Chen, Hongyue Xu, Lingyu Wu, Shulin Li, Chao Wang, Wenjing Luan, Xuefei Wang, Mingyuan Liu, Xudong Tang and Lu Yu

    Citation: Lipids in Health and Disease 2018 17:276

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  33. Content type: Review

    Previous studies have revealed that triglyceride to high-density lipoprotein cholesterol (HDL-C) ratio (henceforth TG/HDL-C) is one of the major risk factors for cardiovascular disease, insulin resistance and ...

    Authors: Yongmei Liu, Peiling Zhao, Mingliang Cheng, Lei Yu, Zhuo Cheng, Linda Fan and Chi Chen

    Citation: Lipids in Health and Disease 2018 17:275

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  34. Content type: Research

    Previous studies have investigated the associations of paraoxonase 1 (PON1) rs854560 polymorphism with plasma lipid levels, but the results are inconclusive. This meta-analysis aimed to clarify the associations o...

    Authors: Zhi Luo, Shujin Li, Irfan Muhammad, Md Rezaul Karim and Yongyan Song

    Citation: Lipids in Health and Disease 2018 17:274

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  35. Content type: Research

    The contributions of inflammation, triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) to the residual risk of cardiovascular events have not been determined in a large cohort of Chinese populat...

    Authors: Wen Dai, Ziyu Zhang and Shuiping Zhao

    Citation: Lipids in Health and Disease 2018 17:273

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  36. Content type: Research

    The rabbit is widely used as an important experimental model for biomedical research, and shows low adipose tissue deposition during growth. Long non-coding RNAs (lncRNAs) are associated with adipose growth, b...

    Authors: Guo-Ze Wang, Kun Du, Shen-Qiang Hu, Shi-Yi Chen, Xian-Bo Jia, Ming-Cheng Cai, Yu Shi, Jie Wang and Song-Jia Lai

    Citation: Lipids in Health and Disease 2018 17:271

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  37. Content type: Research

    We demonstrated growing evidence supports a protective role of chlorogenic acid of rat hepatocytes elicited by two compounds, i.e. thapsigargin and palmitic acid. Nevertheless, little is known about the mechan...

    Authors: Yong Zhang, Liangsheng Miao, Huijuan Zhang, Gang Wu, Zhenni Zhang and Jianrui Lv

    Citation: Lipids in Health and Disease 2018 17:270

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  38. Content type: Research

    This study aimed to determine early postoperative changes of serum sphingomyelin (SM) and ceramide (CER) species following laparoscopic sleeve gastrectomy (LSG).

    Authors: Hakan Özer, İbrahim Aslan, Mehmet Tahir Oruç, Yaşar Çöpelci, Ebru Afşar, Sabriye Kaya and Mutay Aslan

    Citation: Lipids in Health and Disease 2018 17:269

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  39. Content type: Research

    Insulin resistance (IR) is an important risk factor for subclinical atherosclerosis. This study evaluated the relationship between the triglyceride glucose (TyG) index, which is a simple and reliable surrogate...

    Authors: Ki-Bum Won, Gyung-Min Park, Sang-Eun Lee, In-Jeong Cho, Hyeon Chang Kim, Byoung Kwon Lee and Hyuk-Jae Chang

    Citation: Lipids in Health and Disease 2018 17:268

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  40. Content type: Research

    High doses and vegetable origin of lipid emulsions (LE) are prominent factors for liver test (LT) alterations in patients treated with parenteral nutrition (PN). This study aims to determine incidence of LT al...

    Authors: Josep Llop-Talaveron, Maria B. Badia-Tahull, Toni Lozano-Andreu, Ana Suarez-Lledo and Elisabet Leiva-Badosa

    Citation: Lipids in Health and Disease 2018 17:267

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  41. Content type: Research

    Abnormal lipid levels have been suggested as a mechanism leading to atherosclerosis of the lumbar vessels, resulting in low back pain (LBP). This study examined whether abnormal lipid levels were associated wi...

    Authors: Takahiko Yoshimoto, Hirotaka Ochiai, Takako Shirasawa, Satsue Nagahama, Mariko Kobayashi, Akira Minoura, Ayako Miki, Yingli Chen, Hiromi Hoshino and Akatsuki Kokaze

    Citation: Lipids in Health and Disease 2018 17:266

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  42. Content type: Research

    Achievement of low-density lipoprotein cholesterol (LDL-C) goal is the most important for the patients with atherosclerotic cardiovascular diseases (ASCVD) who received lipid-lowering therapy. It is unclear th...

    Authors: Na-Qiong Wu, Yuan-Lin Guo, Cheng-Gang Zhu, Ying Gao, Xi Zhao, Di Sun, Jing Sun, Rui-Xia Xu, Geng Liu, Qian Dong and Jian-Jun Li

    Citation: Lipids in Health and Disease 2018 17:265

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  43. Content type: Research

    Fish intake has been postulated to reduce the risk of stroke. However, whether the beneficial effect of fish are mainly linked to fat content, as a source of omega-3 polyunsaturated fatty acids, remains unclea...

    Authors: Zhi-Zhen Qin, Jia-Ying Xu, Guo-Chong Chen, Yu-Xia Ma and Li-Qiang Qin

    Citation: Lipids in Health and Disease 2018 17:264

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  44. Content type: Research

    Metabolic syndrome is a common extrapulmonary comorbidity in patients with chronic obstructive pulmonary disease (COPD). However, the reported relationship of COPD with dyslipidemia, an important component of ...

    Authors: Lingling Xuan, Feifei Han, Lili Gong, Yali Lv, Zirui Wan, He Liu, Dongsu Zhang, Yangjie Jia, Song Yang, Lulu Ren and Lihong Liu

    Citation: Lipids in Health and Disease 2018 17:263

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  45. Content type: Research

    Triglyceride and glucose (TyG) index and nonalcoholic fatty liver disease (NAFLD) both bave been related to insulin resistance (IR). The study aimed to investigate the longitudinal relationship between TyG ind...

    Authors: Rongjiong Zheng, Zhennan Du, Mingming Wang, Yushan Mao and Wenjie Mao

    Citation: Lipids in Health and Disease 2018 17:262

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