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  1. Recent studies have shown that some glycosyltransferases are involved in the development of nonalcoholic fatty liver disease ( NAFLD). The objective of this study was to explore the effect and mechanism of glycos...

    Authors: Yutao Zhan, Fei Zhao, Ping Xie, Leping Zhong, Dongnian Li, Qujing Gai, Li Li, Hongshan Wei, Lingqiang Zhang and Wei An
    Citation: Lipids in Health and Disease 2015 14:43
    Content type: Research Published on:

  2. Visceral fat accumulation is associated with metabolic disease. It is therefore relevant to study factors that regulate adipose tissue distribution. Recent data shows that overeating saturated fatty acids prom...

    Authors: Paul Petrus, Fredrik Rosqvist, David Edholm, Niklas Mejhert, Peter Arner, Ingrid Dahlman, Mikael Rydén, Magnus Sundbom and Ulf Risérus
    Citation: Lipids in Health and Disease 2015 14:42
    Content type: Short report Published on:

  3. Asymmetric Dimethylarginine (ADMA) is an inhibitor of endogenous nitric oxide synthase, which is the key synthase for nitric oxide (NO) production. Whether statins could protect endothelium by reducing ADMA co...

    Authors: Dongdan Zheng, Qing Liang, FanFang Zeng, Zhuocheng Mai, Anping Cai, Ruofeng Qiu, Rulin Xu, Dongjuan Li and Weiyi Mai
    Citation: Lipids in Health and Disease 2015 14:41
    Content type: Research Published on:

  4. Recent evidence points to an increased incidence of new-onset diabetes and a negative impact on glucose parameters with statin use. This study examined the safety of ezetimibe vs placebo for change from baseli...

    Authors: Itori Saito, Kyoichi Azuma, Taro Kakikawa, Nobuyuki Oshima, Mary E Hanson and Andrew M Tershakovec
    Citation: Lipids in Health and Disease 2015 14:40
    Content type: Research Published on:

  5. Nonalcoholic fatty liver disease (NAFLD) has emerged as the major pediatric chronic liver disease, and it is estimated to affect more than one third of obese children in the U.S. Cardiovascular complications a...

    Authors: Ran Jin, Ngoc-Anh Le, Rebecca Cleeton, Xiaoyan Sun, Jessica Cruz Muños, James Otvos and Miriam B Vos
    Citation: Lipids in Health and Disease 2015 14:39
    Content type: Research Published on:

  7. Elevated cholesterol in type 2 diabetes mellitus (DM) can cause endothelial dysfunction. An effective clinical therapy to improve endothelial dysfunction remains to be established. Different cardiovascular act...

    Authors: Seigo Sugiyama, Hideaki Jinnouchi, Kunio Hieshima, Noboru Kurinami, Tomoko Suzuki, Fumio Miyamoto, Keizo Kajiwara, Kunihiko Matsui and Tomio Jinnouchi
    Citation: Lipids in Health and Disease 2015 14:37
    Content type: Research Published on:

  8. Consumers are becoming increasingly interested in food containing high concentration of polyunsaturated fatty acids (PUFA). PUFA are considered as functional ingredients to prevent cardiovascular disease. The ...

    Authors: Xiudong Liao, Rujuan Wu, Guang Ma, Longmei Zhao, Zhaojun Zheng and Rijun Zhang
    Citation: Lipids in Health and Disease 2015 14:36
    Content type: Research Published on:

  9. Dyslipidemia is one factor cited for increased risk of cardiovascular disease (CVD) in American football players. However, American football players undergo physical conditioning which is known to influence li...

    Authors: Jonathan M Oliver, Dustin P Joubert, Aaron Caldwell, Steve E Martin and Stephen F Crouse
    Citation: Lipids in Health and Disease 2015 14:35
    Content type: Research Published on:

  10. The beta-3 adrenergic receptor (β3-AR) Trp64Arg and uncoupling protein 1 (UCP1) -3826 A > G polymorphisms have been reported to be associated with obesity and/or lipid metabolism in some populations. This study e...

    Authors: Yihong Chen, Xiaosu Wang, Zheni Shen, Ping Fan, Rui Liu, Yu Liu, Rongmei Ren, Lei Ma and Huai Bai
    Citation: Lipids in Health and Disease 2015 14:34
    Content type: Research Published on:

  12. Studies of the association between the apolipoprotein C3 gene (APOC3) rs5128 polymorphism and plasma levels of apolipoprotein C3 (APOC3) and lipids have reported apparently conflicting findings. This meta-analysi...

    Authors: Yongyan Song, Liren Zhu, Mudwari Richa, Ping Li, Yang Yang and Suping Li
    Citation: Lipids in Health and Disease 2015 14:32
    Content type: Research Published on:

  13. In recent years, much evidence suggested that vitamin D plays an important role in decreasing the risk of type 2 diabetes. The purpose of this study was to investigate whether 1, 25 (OH) 2D3 can modulate inflamma...

    Authors: Conghua Ning, Lina Liu, Guodong Lv, Ye Yang, Yuanyuan Zhang, Rui Yu, Yongtao Wang and Jun Zhu
    Citation: Lipids in Health and Disease 2015 14:31
    Content type: Research Published on:

  14. Plasma low density lipoprotein (LDL) particles vary in size, density, electrical charge and chemical composition. An increased presence of small dense LDL (sdLDL), along with raised triglyceride concentrations...

    Authors: Sirikul Kulanuwat, Rungsunn Tungtrongchitr, David Billington and Ian G Davies
    Citation: Lipids in Health and Disease 2015 14:30
    Content type: Research Published on:

  15. Cardiovascular disease (CVD) risk is substantially increased in subjects with chronic kidney disease (CKD). The Triglycerides (TG) to High-Density Lipoprotein Cholesterol (HDL-C) ratio is an indirect measure o...

    Authors: Alper Sonmez, Mahmut Ilker Yilmaz, Mutlu Saglam, Hilmi Umut Unal, Mahmut Gok, Hakki Cetinkaya, Murat Karaman, Cem Haymana, Tayfun Eyileten, Yusuf Oguz, Abdulgaffar Vural, Manfredi Rizzo and Peter P Toth
    Citation: Lipids in Health and Disease 2015 14:29
    Content type: Research Published on:

  16. High serum Retinol Binding Protein 4 (RBP4) levels were associated with insulin-resistant states in humans. To determine which fat compartments are associated with elevated RBP4 levels in humans, we measured s...

    Authors: Xinxia Chang, Hongmei Yan, Hua Bian, Mingfeng Xia, Linshan Zhang, Jian Gao and Xin Gao
    Citation: Lipids in Health and Disease 2015 14:28
    Content type: Research Published on:

  18. Several studies show that the consumption of vegetable oils, such as soybean oil, rich in polyunsaturated fatty acids (PUFAs) has beneficial health effects by preventing or reducing the risk factors of cardiov...

    Authors: Taisla Soprani, Vinicius Kuffer Uliana, Rogerio Faustino Ribeiro, Sergio Lisboa, Gabriella Xavier Maretto, André Teixeira Silva da Ferreira, Jonas Perales, Ivanita Stefanon and Suely Gomes de Figueiredo
    Citation: Lipids in Health and Disease 2015 14:26
    Content type: Research Published on:

  19. Apolipoprotein E (ApoE) participates in lipoprotein metabolism and immune regulation. This study assessed association between ApoE polymorphisms with hyperuricemia and uric acid metabolism in Uygur men, Xinjiang,...

    Authors: Yu-Ping Sun, Bei Zhang, Lei Miao, Xian-Min Wang, Jia-Hui Yu, Li Luo, Lu Ying, Gao Xin, Gulinizha Haliakpaer, He Xia and Hua Yao
    Citation: Lipids in Health and Disease 2015 14:25
    Content type: Research Published on:

  20. Metabolic syndrome (MetS) is associated with carotid intima-media thickness (CIMT), which is a good predictor of cardiovascular disease (CVD). However, among individuals with MetS, direct comparative data rega...

    Authors: Guangming Qin, Jiangfeng Tu, Chenjing Zhang, Xiaoxiao Tang, Laisheng Luo, Jiaqi Wu, Lingang Liu, Wen Lu, Lisha Tao, Shengrong Shen, Undurti N Das and Wensheng Pan
    Citation: Lipids in Health and Disease 2015 14:24
    Content type: Research Published on:

  21. There have been several meta-analyses evaluating the effect of n-3 polyunsaturated fatty acids (PUFAs) in critically ill patients, but of these, none focused on patients with systemic inflammatory response syn...

    Authors: Xiao Wan, Xuejin Gao, Jingcheng Bi, Feng Tian and Xinying Wang
    Citation: Lipids in Health and Disease 2015 14:23
    Content type: Review Published on:

  22. Low serum cholesterol levels are related to an increased risk of depression and its serious consequences. However, the effect of central cholesterol on depressive disorder and its potential regulatory mechanis...

    Authors: Shuqin Sun, Shuo Yang, Yongjun Mao, Xiujuan Jia and Zheng Zhang
    Citation: Lipids in Health and Disease 2015 14:22
    Content type: Research Published on:

  24. Lactobacillus gasseri SBT2055 (LG2055) has been shown to prevent abdominal adiposity, and suppression of lipid absorption is considered a possible mechanism, detail of which, however, are poorly understood. In th...

    Authors: Akihiro Ogawa, Toshiya Kobayashi, Fumihiko Sakai, Yukio Kadooka and Yoshihiro Kawasaki
    Citation: Lipids in Health and Disease 2015 14:20
    Content type: Research Published on:

  25. Krill contains two marine omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), mainly bound in phospholipids. Typical products from krill are krill oil and krill mea...

    Authors: Anton Köhler, Essi Sarkkinen, Niina Tapola, Tarja Niskanen and Inge Bruheim
    Citation: Lipids in Health and Disease 2015 14:19
    Content type: Research Published on:

  26. Testosterone deficiency is associated with increased serum cholesterol levels. However, how testosterone deficiency precisely affects cholesterol metabolism remains unclear. Therefore, in the current study, we...

    Authors: Zhaowei Cai, Haitao Xi, Yongming Pan, Xiaoling Jiang, Liang Chen, Yueqin Cai, Keyan Zhu, Cheng Chen, Xiaoping Xu and Minli Chen
    Citation: Lipids in Health and Disease 2015 14:18
    Content type: Research Published on:

  27. The +294T/C polymorphism in the peroxisome proliferator-activated receptor delta (PPARD) gene is associated with hyperlipidemia in several younger populations, but results are still inconsistence across ethnic...

    Authors: Chen-Yuan Luo, Cheng-Wu Liu, Lin Ge, Guo-Fang Pang, Ming Yang, Cai-You Hu, Ze-Ping Lv, Ning-Yuan Chen, Hai-Yan Li, Hua-Yu Wu, Yi-Yuan Wang, Rui-Xing Yin, Shang-Ling Pan and Jun-Hua Peng
    Citation: Lipids in Health and Disease 2015 14:17
    Content type: Research Published on:

  28. CYP17A1 gene encodes P450c17 proteins, which is a key enzyme that catalyzes the formation of sex hormones. Many clinical studies showed that sex hormones levels play an important role in the pathogenesis of co...

    Authors: Chuan-Fang Dai, Xiang Xie, Yi-Ning Yang, Xiao-Mei Li, Ying-Ying Zheng, Zhen-Yan Fu, Fen Liu, Bang-Dang Chen, Min-Tao Gai and Yi-Tong Ma
    Citation: Lipids in Health and Disease 2015 14:16
    Content type: Research Published on:

  29. The current perspective for the search of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitor has been shifted towards a natural agent also having antioxidant property. Thus, this study was in...

    Authors: Danish Iqbal, M Salman Khan, Mohd Sajid Khan, Saheem Ahmad, Md Sarfaraj Hussain and Mohd Ali
    Citation: Lipids in Health and Disease 2015 14:15
    Content type: Research Published on:

  30. Alpha linolenic acid (ALA, 18:3) in maternal diets has been shown to attenuate obesity associated insulin resistance (IR) in adult offspring in mice. The objective in the present study was to detect the early ...

    Authors: Limor Shomonov-Wagner, Amiram Raz and Alicia Leikin-Frenkel
    Citation: Lipids in Health and Disease 2015 14:14
    Content type: Research Published on:

  32. Fish oil-derived long-chain omega-3 (n-3) polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), reduce plasma triglyceride (TG) levels. Genetic factors such...

    Authors: Bénédicte L Tremblay, Hubert Cormier, Iwona Rudkowska, Simone Lemieux, Patrick Couture and Marie-Claude Vohl
    Citation: Lipids in Health and Disease 2015 14:12
    Content type: Research Published on:

  33. Numerous studies on animals evidenced that conjugated linoleic acid (CLA) could decrease blood pressure (BP) in several rat models. However, such beneficial effect is not completely supported by studies on hum...

    Authors: Jing Yang, Hai-Peng Wang, Ling-Mei Zhou, Li Zhou, Tan Chen and Li-Qiang Qin
    Citation: Lipids in Health and Disease 2015 14:11
    Content type: Review Published on:

  34. Dyslipidemia management situation in Chinese patients with high risk and very high risk has been demonstrated very low, despite the wide use of statins. The effects and safety of the combined treatment of ezet...

    Authors: Lulu Li, Minli Zhang, Fuxiang Su, Yang Li, Yali Shen, Jie Shen and Daqing Zhang
    Citation: Lipids in Health and Disease 2015 14:10
    Content type: Research Published on:

  35. Thrombosis and immune dysfunction are two important complications that result from the administration of parenteral nutrition. Endothelial cells within the vasculature are crucial components necessary for main...

    Authors: Kevin A Harvey, Zhidong Xu, Thomas M Pavlina, Gary P Zaloga and Rafat A Siddiqui
    Citation: Lipids in Health and Disease 2015 14:9
    Content type: Research Published on:

  36. Familial chylomicronemia syndrome (FCS) is a rare lipid disease caused by complete lipoprotein lipase (LPL) deficiency resulting in fasting chylomicronemia and severe hypertriglyceridemia. Inhibition of diacyl...

    Authors: Charles Daniel Meyers, Karine Tremblay, Ahmed Amer, Jin Chen, Liewen Jiang and Daniel Gaudet
    Citation: Lipids in Health and Disease 2015 14:8
    Content type: Research Published on:

  37. Sodium metabisulfite is commonly used as preservative in foods but can oxidize to sulfite radicals initiating molecular oxidation. Ghrelin is a peptide hormone primarily produced in the stomach and has anti-in...

    Authors: Sevim Ercan, Ceren Kencebay, Goksun Basaranlar, Filiz Ozcan, Narin Derin and Mutay Aslan
    Citation: Lipids in Health and Disease 2015 14:7
    Content type: Research Published on:

  38. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) show beneficial effects on cardiovascular health and cognitive functions, but the underlying molecular mechanisms are not completely understood. Because of the f...

    Authors: Simone Schmidt, Janina Willers, Sabine Riecker, Katharina Möller, Jan Philipp Schuchardt and Andreas Hahn
    Citation: Lipids in Health and Disease 2015 14:4
    Content type: Research Published on:

  39. It is widely known that salt is an accelerating factor for the progression of metabolic syndrome and causes cardiovascular diseases, most likely due to its pro-oxidant properties. We hypothesized that excessiv...

    Authors: Yuzaburo Uetake, Hitoshi Ikeda, Rie Irie, Kazuaki Tejima, Hiromitsu Matsui, Sayoko Ogura, Hong Wang, ShengYu Mu, Daigoro Hirohama, Katsuyuki Ando, Tatsuya Sawamura, Yutaka Yatomi, Toshiro Fujita and Tatsuo Shimosawa
    Citation: Lipids in Health and Disease 2015 14:6
    Content type: Research Published on:

  40. Extra-virgin olive oil (EVOO) represents an important food in Mediterranean diet due to its favorable effects on human and animal health derived from the consumption of polyphenols. We studied the effects of d...

    Authors: Vito Laudadio, Edmondo Ceci, Nunzia M B Lastella and Vincenzo Tufarelli
    Citation: Lipids in Health and Disease 2015 14:5
    Content type: Research Published on:

  41. Arachidonic acid (ARA) is an essential fatty acid and a major constituent of biomembranes. It is converted into various lipid mediators, such as prostaglandin E2 (PGE2), which is involved in the development of rh...

    Authors: Norifumi Tateishi, Yoshihisa Kaneda, Saki Kakutani, Hiroshi Kawashima, Hiroshi Shibata and Ikuo Morita
    Citation: Lipids in Health and Disease 2015 14:3
    Content type: Research Published on:

  42. Irisin is a newly discovered exercise-mediated myokine which regulates energy metabolism and has been the subject of much recent research. Irisin plays an important role in metabolic diseases making it a poten...

    Authors: Jia-qi Chen, Yue-ye Huang, Aaron M Gusdon and Shen Qu
    Citation: Lipids in Health and Disease 2015 14:2
    Content type: Review Published on:

  43. Ezetimibe ameliorates serum low-density lipoprotein cholesterol (LDL-c) and it has been approved for the treatment of hypercholesterolemia. However, the effects of ezetimibe on specific biomarkers have not bee...

    Authors: Hisashi Adachi, Hitoshi Nakano, Kiichiro Yamamoto, Masashi Nakata, Hisatoshi Bekki, Tomoki Honma, Hideki Yoshiyama and Masatoshi Nohara
    Citation: Lipids in Health and Disease 2015 14:1
    Content type: Research Published on:

  44. Evidence from in vitro and animal studies indicates that conjugated linoleic acid (CLA) possesses anti-diabetic properties, which appear to be attributed to cis-9, trans-11 CLA, the major CLA isomer in ruminant f...

    Authors: Mariana Macedo de Almeida, Sheila Cristina Potente Dutra Luquetti, Céphora Maria Sabarense, José Otávio do Amaral Corrêa, Larissa Gomes dos Reis, Ellen Paula Santos da Conceição, Patrícia Cristina Lisboa, Egberto Gaspar de Moura, Jacy Gameiro, Marco Antônio Sundfeld da Gama, Fernando César Ferraz Lopes and Raúl Marcel González Garcia
    Citation: Lipids in Health and Disease 2014 13:200
    Content type: Research Published on:

  45. Palmitoleic acid was previously shown to improve glucose homeostasis by reducing hepatic glucose production and by enhancing insulin-stimulated glucose uptake in skeletal muscle. Herein we tested the hypothesi...

    Authors: Andressa Bolsoni-Lopes, William T Festuccia, Patricia Chimin, Talita SM Farias, Francisco L Torres-Leal, Maysa M Cruz, Paula B Andrade, Sandro M Hirabara, Fabio B Lima and Maria Isabel C Alonso-Vale
    Citation: Lipids in Health and Disease 2014 13:199
    Content type: Research Published on:

  46. Micronutrients in oil reduce one or more risk factors of cardiovascular diseases, while the contents of micronutrients in oil are relatively poor, which is insufficient to reverse the metabolic disorders at di...

    Authors: Qianchun Deng, Xiao Yu, Jiqu Xu, Lan Wang, Fenghong Huang, Qingde Huang, Changsheng Liu and Fangli Ma
    Citation: Lipids in Health and Disease 2014 13:198
    Content type: Research Published on:

  48. Ingestion of polyunsaturated fatty acids (PUFAs) has been proposed to influence several chronic diseases including coronary heart disease (CHD) and type-2 diabetes (T2D). There is strong evidence that omega-3 ...

    Authors: Tammy C Lee, Priscilla Ivester, Austin G Hester, Susan Sergeant, Larry Douglas Case, Timothy Morgan, Ethel O Kouba and Floyd H Chilton
    Citation: Lipids in Health and Disease 2014 13:196
    Content type: Research Published on:

  49. Recent studies have demonstrated a relationship between fructose consumption and risk of developing metabolic syndrome. Mechanisms by which dietary fructose mediates metabolic changes are poorly understood. Th...

    Authors: Faizan Jameel, Melinda Phang, Lisa G Wood and Manohar L Garg
    Citation: Lipids in Health and Disease 2014 13:195
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X