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  1. Hypercholesterolemia coexisting with diabetes still requires clinical intervention to manage the high risk of cardiovascular disease it poses. No second-step strategy is established, however, for cases where s...

    Authors: Takeshi Inazawa, Kentaro Sakamoto, Takahide Kohro, Raisuke Iijima, Toru Kitazawa, Tsutomu Hirano, Mitsunobu Kawamura, Motoki Tagami, Akira Tanaka, Yasumichi Mori, Tsutomu Yamazaki and Teruo Shiba
    Citation: Lipids in Health and Disease 2013 12:142
  2. Dietary supplementation with botanical oils that contain n-6 and n-3 eighteen carbon chain (18C)-PUFA such as γ linolenic acid (GLA, 18:3n-6), stearidonic acid (SDA, 18:4n-3) and α linolenic acid (ALA, 18:3n-3...

    Authors: Jonathan P Arm, Joshua A Boyce, Lin Wang, Heng Chhay, Muhammad Zahid, Vaishali Patil, Usha Govindarajulu, Priscilla Ivester, Kelly L Weaver, Susan Sergeant, Elliot Israel and Floyd H Chilton
    Citation: Lipids in Health and Disease 2013 12:141
  3. High consumption of fish carries a lower risk of cardiovascular disease as a consequence of dietary omega-3 long chain polyunsaturated fatty acid (n-3 PUFA; especially EPA and DHA) content. A controversy exist...

    Authors: Laura Lluís, Núria Taltavull, Mònica Muñoz-Cortés, Vanesa Sánchez-Martos, Marta Romeu, Montse Giralt, Eunice Molinar-Toribio, Josep Lluís Torres, Jara Pérez-Jiménez, Manuel Pazos, Lucía Méndez, José M Gallardo, Isabel Medina and M Rosa Nogués
    Citation: Lipids in Health and Disease 2013 12:140
  4. C5L2, a G protein-coupled receptor (GPCR), has been demonstrated to be a ligand for acylation-stimulating protein (ASP). The aim of the present study is to evaluate the association of a novel variation (901A >...

    Authors: Ying-Ying Zheng, Xiang Xie, Yi-Tong Ma, Yi-Ning Yang, Zhen-Yan Fu, Xiao-Mei Li, Xiang Ma, Bang-Dang Chen and Fen Liu
    Citation: Lipids in Health and Disease 2013 12:139
  5. Although complex multivitamin products are widely used as dietary supplements to maintain health or as special medical food in certain diseases, the effects of these products were not investigated in hyperlipi...

    Authors: Tamás Csont, Márta Sárközy, Gergő Szűcs, Csilla Szűcs, Judit Bárkányi, Péter Bencsik, Renáta Gáspár, Imre Földesi, Csaba Csonka, Csaba Kónya and Péter Ferdinandy
    Citation: Lipids in Health and Disease 2013 12:138
  6. Statins are used to treat hypercholesterolemia in patients with type 2 diabetes mellitus, but many of these patients fail to achieve the target LDL-C level. Recent reports have suggested that a synergistic eff...

    Authors: Keiichi Torimoto, Yosuke Okada, Hiroko Mori, Maiko Hajime, Kenichi Tanaka, Akira Kurozumi, Manabu Narisawa, Sunao Yamamoto, Tadashi Arao, Hirofumi Matsuoka, Nobuo Inokuchi and Yoshiya Tanaka
    Citation: Lipids in Health and Disease 2013 12:137
  7. The metabolic syndrome (MS) is characterized by variable coexistence of metabolic and pathophysiological alterations which are important risk factors for developing of type II diabetes and/or cardiovascular di...

    Authors: Uberdan Guilherme Mendes de Castro, Robson Augusto Souza Augusto Souza dos Santos, Marcelo Eustáquio Silva, Wanderson Geraldo de Lima, Maria José Campagnole-Santos and Andréia Carvalho Alzamora
    Citation: Lipids in Health and Disease 2013 12:136
  8. The apolipoprotein M (APOM) T-778C gene polymorphism has been associated with serum lipid levels and the risk of coronary artery disease (CAD), but the results are inconclusive. The purpose of this meta-analys...

    Authors: Zhi Zhang, Guang Chu and Rui-Xing Yin
    Citation: Lipids in Health and Disease 2013 12:135
  9. Nutritional guidance and diet control play important roles in the treatment of obesity and non-alcoholic fatty liver. However, in Japan, nutritional guidance is difficult to provide in practice. Therefore, we ...

    Authors: Masako Iwamoto, Kaori Yagi, Kayoko Yazumi, Airi Komine, Bungo Shirouchi and Masao Sato
    Citation: Lipids in Health and Disease 2013 12:134
  10. Statin-fibrate combination therapy has been used to treat patients with acute coronary syndrome (ACS) complicated by elevated triglycerides (TG) and decreased high density lipoprotein cholesterol (HDL-C). The ...

    Authors: Xiang-ping Li, Hai-rong Gong, Xian-sheng Huang, Wen-yu Huang and Shui-ping Zhao
    Citation: Lipids in Health and Disease 2013 12:133
  11. Atherosclerosis is a chronic progressive inflammatory disease of blood vessels particularly the arteries. The development of atherosclerotic plaques or atherogenesis is a complex process that is influenced by ...

    Authors: Kriengchai Prasongsukarn, Urai Chaisri, Peenutchanee Chartburus, Kamolwan Wetchabut, Surachet Benjathummarak, Vasant Khachansaksumet and Yaowapa Maneerat
    Citation: Lipids in Health and Disease 2013 12:132
  12. The aim of this study was to determine the physiological effects of an high-intensity circuit training (HICT) on several cardiovascular disease risk factors in healthy, overweight middle-aged subjects, and to ...

    Authors: Antonio Paoli, Quirico F Pacelli, Tatiana Moro, Giuseppe Marcolin, Marco Neri, Giuseppe Battaglia, Giuseppe Sergi, Francesco Bolzetta and Antonino Bianco
    Citation: Lipids in Health and Disease 2013 12:131
  13. Serum amyloid A protein (SAA) is both an inflammatory factor and an apolipoprotein. However, the relation between genetic polymorphisms of SAA and cerebral infarction (CI) remains unclear.

    Authors: Li-Jun Zhang, Bin Yuan, He-Hua Li, Sheng-Bo Tao, Hai-Qing Yan, Li Chang and Jian-Hua Zhao
    Citation: Lipids in Health and Disease 2013 12:130
  14. The prevalence of adolescents’ obesity and overweight has dramatically elevated in China. Obese children were likely to insulin resistance and dyslipidemia, which are risk factors of cardiovascular diseases. H...

    Authors: Chun-dan Gong, Qiao-ling Wu, Zheng Chen, Dan Zhang, Zheng-yan Zhao and Yong-mei Peng
    Citation: Lipids in Health and Disease 2013 12:129
  15. It is well known that enhanced production of reactive oxygen species (ROS) leads to oxidative stress observed in atherosclerosis and that ROS can also cause damage in cellular macromolecules, including DNA. Co...

    Authors: Bianca P. Rodrigues, Bianca P. Campagnaro, Camille M. Balarini, Thiago M. C. Pereira, Silvana S. Meyrelles and Elisardo C. Vasquez
    Citation: Lipids in Health and Disease 2013 12:128
  16. Elevated lipoprotein(a) [Lp(a)] levels predict cardiovascular events incidence in patients with coronary artery disease (CAD). Genetic variants in the rs3798220, rs10455872 and rs6415084 single-nucleotide poly...

    Authors: Zhi-Gen Li, Guang Li, Ying-Ling Zhou, Zhu-Jun Chen, Jun-Qing Yang, Ying Zhang, Shuo Sun and Shi-Long Zhong
    Citation: Lipids in Health and Disease 2013 12:127
  17. Statins (HMG-CoA reductase inhibitors) represent a major class of compounds for the treatment of hypercholesterolemia due to their ability to inhibit de novo cholesterol synthesis. In addition to their hypolipide...

    Authors: Helena Gbelcová, Martin Švéda, Lucia Laubertová, Ivan Varga, Libor Vítek, Michal Kolář, Hynek Strnad, Jaroslav Zelenka, Daniel Böhmer and Tomáš Ruml
    Citation: Lipids in Health and Disease 2013 12:126
  18. Diets enriched with sphingolipids may improve blood lipid profiles. Studies in animals have shown reductions in cholesterol absorption and alterations in blood lipids after treatment with sphingomyelin (SM). H...

    Authors: Vanu R. Ramprasath, Peter J. H. Jones, Donna D. Buckley, Laura A. Woollett and James E. Heubi
    Citation: Lipids in Health and Disease 2013 12:125
  19. Various flavonoids obtained from the genus Cirsium have been reported to exhibit beneficial effects on health. The present study evaluated the antiobesity effects of Cirsium brevicaule A. GRAY leaf (CL) by using ...

    Authors: Masashi Inafuku, Ruwani N. Nugara, Yasuo Kamiyama, Itsuki Futenma, Ayako Inafuku and Hirosuke Oku
    Citation: Lipids in Health and Disease 2013 12:124
  20. Various inflammatory mediators related to obesity might be closely related to insulin resistance. Leukotrienes (LTs) are involved in inflammatory reactions. However, there are few reports regarding the role of...

    Authors: Kae Hirata, Koichiro Wada, Yuka Murata, Atsushi Nakajima, Takashi Yamashiro and Yoshinori Kamisaki
    Citation: Lipids in Health and Disease 2013 12:122
  21. Hypercholesterolemia and oxidative stress are the main stimulating factors responsible for coronary artery disease and progression of atherosclerosis. Dairy food products are rich in conjugated linoleic acid (...

    Authors: Kathirvelan Chinnadurai, Harpreet Kaur Kanwal, Amrish Kumar Tyagi, Catherine Stanton and Paul Ross
    Citation: Lipids in Health and Disease 2013 12:121
  22. Dyslipidemia is one of several known risk factors for coronary heart disease, a leading cause of death in Lithuania. Blood lipid levels are influenced by multiple genetic and environmental factors. Epidemiolog...

    Authors: Alina Smalinskiene, Janina Petkeviciene, Dalia Luksiene, Kristina Jureniene, Jurate Klumbiene and Vaiva Lesauskaite
    Citation: Lipids in Health and Disease 2013 12:120
  23. This study investigated the hypothesis that long-term orange juice consumption (≥ 12 months) was associated with low risk factors for cardiovascular disease in adult men and women with normal and moderately hi...

    Authors: Nancy P. Aptekmann and Thais B. Cesar
    Citation: Lipids in Health and Disease 2013 12:119
  24. The theory of Chinese medicine believes rage harms normal liver function, namely ’raged impairing liver' in short. The purpose of this study is to investigate the impact of acute stress on liver lipid metaboli...

    Authors: Xiaoling Gao, Yuaner Zeng, Shuqiang Liu and Shuling Wang
    Citation: Lipids in Health and Disease 2013 12:118
  25. Early preclinical diagnosis of COPD is urgent. We proposed that fatty acid composition of red blood cells may serve as a prognostic test for the complications in the chronic respiratory diseases. Fatty acid co...

    Authors: Tatyana P. Novgorodtseva, Yulia K. Denisenko, Natalia V. Zhukova, Marina V. Antonyuk, Vera V. Knyshova and Tatyana A. Gvozdenko
    Citation: Lipids in Health and Disease 2013 12:117
  26. Serum amyloid A (SAA) is a kind of apolipoprotein. Several studies indicated that SAA genetic polymorphism rs12218 was associated with carotid atherosclerosis, peripheral arterial disease, and serum uric acid ...

    Authors: Xiao-Lin Xu, Xiao-Tian Sun, Liewen Pang, Guoqian Huang, Jiechun Huang, Meng Shi and Yi-Qing Wang
    Citation: Lipids in Health and Disease 2013 12:116
  27. Atherosclerosis has been widely accepted as an inflammatory disease of vascular, adhesion molecules play an important role in the early progression of it. The aim of the present study was to evaluate the effec...

    Authors: Lingxi Kong, Cheng Luo, Xiuying Li, Yuanda Zhou and Haixia He
    Citation: Lipids in Health and Disease 2013 12:115
  28. The Daniel Fast involves dietary modification similar to a purified vegan diet. Although improvements in several health-specific biomarkers have been noted with this plan, the removal of animal products result...

    Authors: Rick J. Alleman Jr, Innocence C. Harvey, Tyler M. Farney and Richard J. Bloomer
    Citation: Lipids in Health and Disease 2013 12:114
  29. Polyunsaturated fatty acids (PUFA) play important roles in brain fatty acid composition and behavior through their effects on neuronal properties and gene expression. The hippocampus plays an important role in...

    Authors: Toktam Hajjar, Yong Meng Goh, Mohamed Ali Rajion, Sharmili Vidyadaran, Tan Ai Li and Mahdi Ebrahimi
    Citation: Lipids in Health and Disease 2013 12:113
  30. Studies in animals showed that PCSK9 is involved in HDL metabolism. We investigated the molecular mechanism by which PCSK9 regulates HDL cholesterol concentration and also whether Pcsk9 inactivation might affect ...

    Authors: Seungbum Choi, Aleksandra Aljakna, Ujala Srivastava, Blake R Peterson, Bin Deng, Annik Prat and Ron Korstanje
    Citation: Lipids in Health and Disease 2013 12:112
  31. Polyunsaturated fatty acids (PUFAs) have positive effect on the regulation of plasma lipids. But the mechanism for them to modulate lipid homeostasis in macrophage is still unclear. In this study, we employed ...

    Authors: Yue Song, Li-Jun Zhang, Hang Li, Yu Gu, Fan-Fan Li, Li-Na Jiang, Fang Liu, Jing Ye and Qing Li
    Citation: Lipids in Health and Disease 2013 12:111
  32. Our previous study demonstrated that the A-allele of the single nucleotide polymorphism (SNP) rs34623097 located in the upstream region of the β2 adrenergic receptor gene (ADRB2) is significantly associated with ...

    Authors: Izumi Naka, Jun Ohashi, Ryosuke Kimura, Tsukasa Inaoka and Yasuhiro Matsumura
    Citation: Lipids in Health and Disease 2013 12:110
  33. Over the past two decades, a striking increase in the number of people with metabolic syndrome (MS) has taken place worldwide. With the elevated risk of not only diabetes but also cardiovascular morbidity and ...

    Authors: Xiaofang Liu, Yong Xue, Chunhua Liu, Qiaoming Lou, Jingfeng Wang, Teruyoshi Yanagita, Changhu Xue and Yuming Wang
    Citation: Lipids in Health and Disease 2013 12:109
  34. Hypoadiponectinemia in lipoatrophy may be related to worsening of hypertension in stroke-prone spontaneously hypertensive rats (SHRSP). One of the beneficial effects of candesartan (Angiotensin II Type 1 recep...

    Authors: Kumiko Takemori, Takao Inoue and Hiroyuki Ito
    Citation: Lipids in Health and Disease 2013 12:108
  35. It is now established that patients with hyperlipidemia have a high risk of atherosclerosis and thrombotic complications, which are two important events responsible for the onset and progression of cardiovascu...

    Authors: Adil Haimeur, Hafida Messaouri, Lionel Ulmann, Virginie Mimouni, Azelarab Masrar, Abdelmjid Chraibi, Gérard Tremblin and Nadia Meskini
    Citation: Lipids in Health and Disease 2013 12:107
  36. During postprandial state, TG concentration is increasing and HDL cholesterol decreasing, leading to a transitory pro-atherosclerotic profile. Previous studies have reported that bicarbonate water improve post...

    Authors: Yassine Zair, Fatima Kasbi-Chadli, Beatrice Housez, Mathieu Pichelin, Murielle Cazaubiel, François Raoux and Khadija Ouguerram
    Citation: Lipids in Health and Disease 2013 12:105
  37. Excessive circular fatty acid, particlarly saturated fatty acid, can result in insulin resistance in skeletal muscle, but other adverse effects of fatty acid accumulation in myocytes remain unclear.

    Authors: Ming Yang, Dandan Wei, Chunfen Mo, Jie Zhang, Xu Wang, Xiaojuan Han, Zhe Wang and Hengyi Xiao
    Citation: Lipids in Health and Disease 2013 12:104
  38. This post hoc analysis assessed switching to ezetimibe/simvastatin 10/20 mg vs doubling the baseline statin dose to simvastatin 40 mg or atorvastatin 20 mg or switching to rosuvastatin 10 mg in subgroups of obese...

    Authors: Jeffrey B. Rosen, Jose G. Jimenez, Valdis Pirags, Hella Vides, Rachid Massaad, Mary E. Hanson, Philippe Brudi and Joseph Triscari
    Citation: Lipids in Health and Disease 2013 12:103
  39. The long-chain n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have human health benefits. Alternatives to fish as sources of EPA and DHA are needed. Oil from the micro-algae Nannochlor...

    Authors: Michael L. Kagan, Annette L. West, Christa Zante and Philip C. Calder
    Citation: Lipids in Health and Disease 2013 12:102
  40. Omega-3 PUFAs are known to have anti-inflammatory properties, and different mechanisms are involved. GPR120 is a G-protein coupled receptor that has recently received attention because of its anti-inflammatory...

    Authors: Kaia Mobraten, Trude M. Haug, Charlotte R. Kleiveland and Tor Lea
    Citation: Lipids in Health and Disease 2013 12:101
  41. The association of adverse health with high fat intake has long been recognized. However, the lack of research focusing on the interrelationship of thyroid and liver function, and the pathogenesis of a high fa...

    Authors: Venus Welch-White, Norma Dawkins, Thomas Graham and Ralphenia Pace
    Citation: Lipids in Health and Disease 2013 12:100
  42. There is considerable interest in dairy products from low-input systems, such as mountain-pasture grazing cows, because these products are believed to be healthier than products from high-input conventional sy...

    Authors: Louise B. Werner, Lars I. Hellgren, Marianne Raff, Søren K. Jensen, Rikke A. Petersen, Tue Drachmann and Tine Tholstrup
    Citation: Lipids in Health and Disease 2013 12:99
  43. Diabetes mellitus is a metabolic disease with multiple complications that causes serious diseases over the years. The condition leads to severe economic consequences and is reaching pandemic level globally. Mu...

    Authors: Sehamuddin Galadari, Anees Rahman, Siraj Pallichankandy, Alaa Galadari and Faisal Thayyullathil
    Citation: Lipids in Health and Disease 2013 12:98
  44. The association of genetic polymorphisms of Tanis with triglyceride concentration in human has not been thoroughly examined. We aimed to investigate the relationship between triglyceride concentrations and Tan...

    Authors: Ying Gao, Xiang Xie, Yi-Tong Ma, Yi-Ning Yang, Xiao-Mei Li, Zhen-Yan Fu, Ying-Ying Zheng, Xiang Ma, Bang-Dang Chen, Fen Liu and Ying Huang
    Citation: Lipids in Health and Disease 2013 12:97
  45. Conjugated linoleic acids (CLA) in general, and in particular the trans- 10,cis- 12 (t 10,c 12-CLA) isomer are potent modulators of milk fat synthesis in dairy cows. Studies in rodents, such as mice, have reveale...

    Authors: Ronny Kramer, Simone Wolf, Tobias Petri, Dirk von Soosten, Sven Dänicke, Eva-Maria Weber, Ralf Zimmer, Juergen Rehage and Gerhard Jahreis
    Citation: Lipids in Health and Disease 2013 12:96
  46. Epidemiological studies have verified the protective role of fish lipids in cardiovascular diseases. However, the effects of fish lipids on health boost remain undefined. Large amounts of by-products, such as ...

    Authors: Caixia Wang, Wenshui Xia, Yanshun Xu, Qixing Jiang, Shanshan Yin, Yuwei Yang and Peipie Yu
    Citation: Lipids in Health and Disease 2013 12:94
  47. To evaluate whether abnormal endothelial function, a common finding in gestational diabetes mellitus (GDM) pregnancies, can be explained by inflammatory cytokines.

    Authors: Ines Mrizak, Amel Arfa, Mariem Fekih, Haythem Debbabi, Ali Bouslema, Imen Boumaiza, Monia Zaouali, Naim A Khan and Zouhair Tabka
    Citation: Lipids in Health and Disease 2013 12:93

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