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  1. Researches have shown that soluble epoxide hydrolase inhibitors (sEHi) can protect against the development of atherosclerosis. Simultaneously, emerging evidences have implicated the association between fatty a...

    Authors: Xuan Zhao, Jian-qing Du, Dan-yan Xu and Shui-ping Zhao
    Citation: Lipids in Health and Disease 2013 12:3
  2. Fatty acid (FA) composition and desaturase indices are associated with obesity and related metabolic conditions. However, it is unclear to what extent desaturase activity in different lipid fractions contribut...

    Authors: Jonathan Cedernaes, Johan Alsiö, Åke Västermark, Ulf Risérus and Helgi B Schiöth
    Citation: Lipids in Health and Disease 2013 12:2
  3. Dyslipidemia increases circulating levels of oxidized low-density lipoprotein (OxLDL) and this may induce alveolar bone loss through toll-like receptor (TLR) 2 and 4. The purpose of this study was to investiga...

    Authors: Takaaki Tomofuji, Daisuke Ekuni, Tetsuji Azuma, Koichiro Irie, Yasumasa Endo, Kenta Kasuyama, Toshiki Yoneda and Manabu Morita
    Citation: Lipids in Health and Disease 2013 12:1
  4. The -493G/T polymorphism in the microsomal triglyceride transfer protein (MTP) gene is associated with lower serum low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) levels and longevity in seve...

    Authors: Shang-Ling Pan, Xiao-Qiu Luo, Ze-Ping Lu, Shao-Hua Lu, Huan Luo, Cheng-Wu Liu, Cai-You Hu, Ming Yang, Li-Li Du, Zhen Song, Guo-Fang Pang, Hua-Yu Wu, Jin-Bo Huang, Jun-Hua Peng and Rui-Xing Yin
    Citation: Lipids in Health and Disease 2012 11:177
  5. A novel herbal formulation LI10903F, alternatively known as LOWAT was developed based on its ability to inhibit adipogenesis and lipogenesis in 3T3-L1 adipocytes model. The clinical efficacy and tolerability o...

    Authors: Krishanu Sengupta, Atmatrana T Mishra, Manikeshwar K Rao, Kadainti VS Sarma, Alluri V Krishnaraju and Golakoti Trimurtulu
    Citation: Lipids in Health and Disease 2012 11:176
  6. On the basis that high fat diet induces inflammation in adipose tissue, we wanted to test the effect of dietary saturated and polysunsaturated fatty acids on human adipose tissue and adipocytes inflammation. M...

    Authors: Ravi Kumar Murumalla, Manoj Kumar Gunasekaran, Jibesh Kumar Padhan, Karima Bencharif, Lydie Gence, Franck Festy, Maya Césari, Régis Roche and Laurence Hoareau
    Citation: Lipids in Health and Disease 2012 11:175
  7. Evidence of the genetic association between CD36 candidate gene and the risk of metabolic syndrome and its components has been inconsistent. This case–control study assessed the haplotype-tagged SNPs from CD36 on...

    Authors: Kuo-Liong Chien, Hsiu-Ching Hsu, Pi-Hua Liu, Hung-Ju Lin and Ming-Fong Chen
    Citation: Lipids in Health and Disease 2012 11:174
  8. The molecular mechanism of how cells maintain cholesterol homeostasis has become clearer for the understanding of complicated association between sterol regulatory element-binding proteins (SREBPs), SREBP clea...

    Authors: Xiao-Ying Dong, Sheng-Qiu Tang and Jin-Ding Chen
    Citation: Lipids in Health and Disease 2012 11:173
  9. Beneficial effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on the lipid levels of dyslipidemic subjects are widely described in the literature. However, the underlying molecular mechanisms are large...

    Authors: Simone Schmidt, Janina Willers, Frank Stahl, Kai-Oliver Mutz, Thomas Scheper, Andreas Hahn and Jan Philipp Schuchardt
    Citation: Lipids in Health and Disease 2012 11:172
  10. In many types of cancer, prostaglandin E2 (PGE2) is associated with tumour related processes including proliferation, migration, angiogenesis and apoptosis. However in gliomas the role of this prostanoid is poorl...

    Authors: Renata N Gomes and Alison Colquhoun
    Citation: Lipids in Health and Disease 2012 11:171
  11. The objectives of the present study were to investigate the efficacy of the mixed culture of Lactobacillus acidophilus (DSM 20242), Bifidobacterium bifidum (DSM 20082) and Lactobacillus helveticus (CK60) in the f...

    Authors: Immaculata Oyeyemi Banjoko, Muinat Moronke Adeyanju, Oladipo Ademuyiwa, Olugbenga Obajimi Adebawo, Rahman Abiodun Olalere, Martin Oluseye Kolawole, Ibrahim Akorede Adegbola, Tope Adebusola Adesanmi, Tosin Oluyinka Oladunjoye, Adeyemi Adeola Ogunnowo, Ahmeed Adekola Shorinola, Oluwasetemi Daropale, Esther Bunmi Babatope, Adeboye Olufemi Osibogun, Deborah Tolulope Ogunfowokan, Temitope Adeola Jentegbe…
    Citation: Lipids in Health and Disease 2012 11:170
  12. Mitochondrial DNA damage, increased production of reactive oxygen species and progressive respiratory chain dysfunction, together with increased deposition of cholesterol and cholesteryl esters, are hallmarks ...

    Authors: Anne Marie Allen and Annette Graham
    Citation: Lipids in Health and Disease 2012 11:169
  13. Administration of androgens decreases plasma concentrations of high-density lipid cholesterol (HDL-C). However, the mechanisms by which androgens mediate lipid metabolism remain unknown. This present study use...

    Authors: Ye Yi-zhou, Cao Bing, Li Ming-qiu, Wang Wei, Wang Ru-xing, Rui Jun, Wei Liu-yan, Jing Zhao-hui, Ji Yong, Jiao Guo qing and Zou Jian
    Citation: Lipids in Health and Disease 2012 11:168
  14. The present study was performed to investigate the effects of the combination therapy of pinocembrin and simvastatin on the atherosclerotic lesions development in the ApoE−/− mice.

    Authors: Hui Sang, Na Yuan, Shutong Yao, Furong Li, Jiafu Wang, Yongqi Fang and Shucun Qin
    Citation: Lipids in Health and Disease 2012 11:166
  15. Given that acne is a rare condition in societies with higher consumption of omega-3 (n-3) relative to omega-6 (n-6) fatty acids, supplementation with n-3 may suppress inflammatory cytokine production and there...

    Authors: Golandam Khayef, Julia Young, Bonny Burns-Whitmore and Thomas Spalding
    Citation: Lipids in Health and Disease 2012 11:165
  16. Accumulating evidence suggested that dysregulation of cholesterol homeostasis might be a major etiologic factor in initiating and promoting neurodegeneration in Alzheimer’s disease (AD). ATP-binding cassette t...

    Authors: Zhijie Xiao, Juan Wang, Weirong Chen, Peng Wang, Houlin Zeng and Weixi Chen
    Citation: Lipids in Health and Disease 2012 11:163
  17. Apolipoprotein (Apo) levels are considered more reliable than plasma lipoprotein levels for predicting coronary artery disease (CAD). However, a unanimous Apo marker for CAD has not been identified. In the Chi...

    Authors: Po-Yuan Chang, Chii-Ming Lee, Hsiu-Ching Hsu, Hung-Ju Lin, Kuo-Liong Chien, Ming-Fong Chen, Chu-Huang Chen, Yuan-Teh Lee and Chao-Yuh Yang
    Citation: Lipids in Health and Disease 2012 11:162
  18. Many disorders with plasmalogen deficiency have been reported. Replenishment or replacement of tissue plasmalogens of these disorders would be beneficial to the patients with these disorders, but effects of di...

    Authors: Shiro Mawatari, Toshihiko Katafuchi, Kiyotaka Miake and Takehiko Fujino
    Citation: Lipids in Health and Disease 2012 11:161
  19. Inflammation is increasingly recognized as being of both physiological and pathological importance in the immature brain. Cerebellar pathology occurs in autism, as a neurodevelopmental disorder with genetic an...

    Authors: Afaf El-Ansary and Laila Al-Ayadhi
    Citation: Lipids in Health and Disease 2012 11:160
  20. The babassu palm tree is native to Brazil and is most densely distributed in the Cocais region of the state of Maranhão, in northeastern Brazil. In addition to the industrial use of refined babassu oil, the mi...

    Authors: Maria do Carmo L Barbosa, Eliete Bouskela, Fátima ZGA Cyrino, Ana Paula S Azevedo, Maria Célia P Costa, Maria das Graças C de Souza, Debora S Santos, Felipe L Barbosa, Luiz Felipe A Guerra and Maria do Desterro SB Nascimento
    Citation: Lipids in Health and Disease 2012 11:158
  21. Considering the importance of long chain polyunsaturated fatty acids to fetal development and the lack of studies that have compared the status of fatty acids between adolescents and adults mothers, the purpos...

    Authors: Olívia RC Oliveira, Michelle G Santana, Flávia S Santos, Felipe D Conceição, Fátima LC Sardinha, Glória V Veiga and Maria G Tavares do Carmo
    Citation: Lipids in Health and Disease 2012 11:157
  22. The purpose of this study was to investigate the effects and mechanisms of dihydrotestosterone (DHT)-induced expression of sterol regulatory element binding protein-1 (SREBP-1), and the synthesis and secretion...

    Authors: Bing-rong Zhou, Qiu-hong Huang, Yang Xu, Di Wu, Zhi-qiang Yin and Dan Luo
    Citation: Lipids in Health and Disease 2012 11:156
  23. Genome wide association studies (GWAS), mostly in Europeans have identified several common variants as associated with key lipid traits. Replication of these genetic effects in South Asian populations is impor...

    Authors: Sajjad Rafiq, Kranthi Kumar M Venkata, Vipin Gupta, DG Vinay, Charles J Spurgeon, Smitha Parameshwaran, Sandeep N Madana, Sanjay Kinra, Liza Bowen, Nicholas J Timpson, George Davey Smith, Frank Dudbridge, Dorairaj Prabhakaran, Yoav Ben-Shlomo, K Srinath Reddy, Shah Ebrahim…
    Citation: Lipids in Health and Disease 2012 11:155
  24. Uncoupling protein 2 (UCP2) was reported to be involved in lipid metabolism through regulating the production of superoxide anion. However, the role of UCP2 in hepatocytes steatosis has not been determined. We...

    Authors: Shuangtao Ma, Dachun Yang, De Li, Yan Tan, Bing Tang and Yongjian Yang
    Citation: Lipids in Health and Disease 2012 11:154
  25. Lipoprotein-associated phospholipase A2 (Lp-PLA2) probably plays an important role in the development of acute coronary syndrome (ACS); elevated levels of Lp-PLA2 are associated with a poorer prognosis in pati...

    Authors: Petr Ostadal, Dagmar Vondrakova, Andreas Kruger, Marek Janotka, Hana Psotova and Miroslav Prucha
    Citation: Lipids in Health and Disease 2012 11:153
  26. This study investigated the effects of salmonella infection and its chemotherapy on lipid metabolism in tissues of rats infected orally with Salmonella typhimurium and treated intraperitoneally with pefloxacin an...

    Authors: Solomon O Rotimi, David A Ojo, Olusola A Talabi, Elizabeth A Balogun and Oladipo Ademuyiwa
    Citation: Lipids in Health and Disease 2012 11:152
  27. Nitric oxide is a key molecule not only in the cardiovascular system, but also in the metabolic-endocrine system. The purpose of this study was to examine possible associations of the NOS3 T-786C polymorphism (rs...

    Authors: Takahiro Higashibata, Nobuyuki Hamajima, Mariko Naito, Sayo Kawai, Guang Yin, Sadao Suzuki, Yoshikuni Kita, Hideshi Niimura, Takeshi Imaizumi, Keizo Ohnaka, Kokichi Arisawa, Masako Shigeta, Hidemi Ito, Haruo Mikami, Michiaki Kubo, Hideo Tanaka…
    Citation: Lipids in Health and Disease 2012 11:150
  28. Atherosclerosis is a major manifestation of the pathophysiology underlying cardiovascular disease. Flaxseed oil (FO) and α-lipoic acid (LA) have been reported to exert potential benefit to cardiovascular syste...

    Authors: Jiqu Xu, Wei Yang, Qianchun Deng, Qingde Huang, Jin’e Yang and Fenghong Huang
    Citation: Lipids in Health and Disease 2012 11:148
  29. Dietary changes are a major factor in determining cardiovascular risk. n-3 polyunsaturated fatty acids modulate the risk factors for metabolic syndrome via multiple mechanisms, including the regulation of the lip...

    Authors: Adil Haimeur, Lionel Ulmann, Virginie Mimouni, Frédérique Guéno, Fabienne Pineau-Vincent, Nadia Meskini and Gérard Tremblin
    Citation: Lipids in Health and Disease 2012 11:147
  30. Hypertriglyceridemia and postprandial hyperlipidemia is thought to play an important role in atherosclerosis, but to select patients at high-risk for cardiovascular diseases is difficult with triglycerides (TG...

    Authors: Tomoki Nagata, Daisuke Sugiyama, Takako Kise, Satomi Tsuji, Hideo Ohira, Itsuko Sato, Mari Yamamoto, Hitomi Kohsaka, Seiji Kawano, Shizuya Yamashita, Yuichi Ishikawa and Yoshio Fujioka
    Citation: Lipids in Health and Disease 2012 11:146

    The Erratum to this article has been published in Lipids in Health and Disease 2014 13:68

  31. Lipid metabolism is altered in subjects with liver steatosis. FAS is a key enzyme in de novo lipogenesis and both FAS gene expression and enzymatic activity are primarily regulated by metabolic signals in the liv...

    Authors: Maria Notarnicola, Giovanni Misciagna, Valeria Tutino, Marisa Chiloiro, Alberto Ruben Osella, Vito Guerra, Caterina Bonfiglio and Maria Gabriella Caruso
    Citation: Lipids in Health and Disease 2012 11:145
  32. Omega-3 fatty acids are important in treatment of severe primary hypertriglyceridemia (HTG). In 15 patients with severe primary HTG (TG >500 mg/dl despite conventional TG lowering therapy), we assessed efficac...

    Authors: Charles J Glueck, Naseer Khan, Muhammad Riaz, Jagjit Padda, Zia Khan and Ping Wang
    Citation: Lipids in Health and Disease 2012 11:143
  33. Polyunsaturated fatty acids are popular dietary supplements advertised to contribute to weight loss by increasing fat metabolism in liver, but the effects on overall muscle metabolism are less established. We ...

    Authors: Roger A Vaughan, Randi Garcia-Smith, Marco Bisoffi, Carole A Conn and Kristina A Trujillo
    Citation: Lipids in Health and Disease 2012 11:142
  34. The association of rs3757354 single nucleotide polymorphism (SNP) in the E3 ubiquitin ligase myosin regulatory light chain-interacting protein (MYLIP, also known as IDOL) gene and serum lipid levels is not wel...

    Authors: Ting-Ting Yan, Rui-Xing Yin, Qing Li, Ping Huang, Xiao-Na Zeng, Ke-Ke Huang, Dong-Feng Wu and Lynn Htet Htet Aung
    Citation: Lipids in Health and Disease 2012 11:141
  35. Atherosclerosis is a chronic degenerative disease of the arteries and is thought to be one of the most common causes of death globally. In recent years, the functions of adventitial fibroblasts in the developm...

    Authors: Jun Wang, Yanfang Si, Chen Wu, Lu Sun, Yudong Ma, Aili Ge and Baomin Li
    Citation: Lipids in Health and Disease 2012 11:139
  36. Type 2 diabetes mellitus (T2DM) is a chronic disease that is characterized by insulin resistance. Its development is directly connected with the inability of insulin to exert its action, not just on carbohydra...

    Authors: Carla Ribeiro, Lucieli Teresa Cambri, Rodrigo Augusto Dalia, Michel Barbosa de Araújo, José Diego Botezelli, Amanda Christine da Silva Sponton and Maria Alice Rostom de Mello
    Citation: Lipids in Health and Disease 2012 11:138
  37. Partly because of functional genomics, there has been a major paradigm shift from solely thinking of skeletal muscle as contractile machinery to an understanding that it can have roles in paracrine and endocri...

    Authors: Theodore W Zderic and Marc T Hamilton
    Citation: Lipids in Health and Disease 2012 11:137
  38. Surgery is the mainstay therapy for HPV-induced laryngeal papillomatosis (LP) and adjuvant therapies are palliative at best. Research revealed that conjugated-linoleic acid (CLA) may improve the outcome of vir...

    Authors: Louise Louw
    Citation: Lipids in Health and Disease 2012 11:136
  39. Cardiomyocytes apoptosis is an important contributor to myocardial dysfunction and heart failure. Adiponectin has cardioprotective effects, potential mechanisms behind it are not clear in cardiomyocytes. The p...

    Authors: Chuan Dong Wei, Yan Li, Hong Yun Zheng, Kai Sheng Sun, Yong Qing Tong, Wen Dai, Wei Wu and An Yu Bao
    Citation: Lipids in Health and Disease 2012 11:135
  40. The aim of the present study was to evaluate the protective effect of concurrent exercise in the degree of the insulin resistance in mice fed with a high-fat diet, and assess adiponectin receptors (ADIPOR1 and...

    Authors: JM Farias, RM Maggi, CB Tromm, LA Silva, TF Luciano, SO Marques, FS Lira, CT de Souza and RA Pinho
    Citation: Lipids in Health and Disease 2012 11:134
  41. Much attention has been drawn to the deleterious effects of adding progestins to estrogen as hormone therapy (HT) in postmenopausal women. Some widely prescribed progestins have been shown to partially oppose ...

    Authors: Gislaine Casanova and Poli Mara Spritzer
    Citation: Lipids in Health and Disease 2012 11:133
  42. Atherogenic dyslipidemia (AD), defined as low HDL-C plus elevated triglycerides (TG), comorbid to T2DM, increases cardiometabolic risk for CAD even when LDL-C is at target. In T2DM males, AD was shown to corre...

    Authors: Michel P Hermans, Sylvie A Ahn and Michel F Rousseau
    Citation: Lipids in Health and Disease 2012 11:132
  43. Obesity is reaching epidemic worldwide and is risk factor for cardiovascular disease and type 2 diabetes. Although plasma high density lipoprotein (HDL) and apolipoprotein A-I (apoA-I) are inversely correlated...

    Authors: Shuai Wang and Daoquan Peng
    Citation: Lipids in Health and Disease 2012 11:131

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