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  1. Cholesterol gallstone disease (GS) is highly prevalent among Hispanics and American Indians. In GS, the pool of bile acids (BA) is decreased, suggesting that BA absorption is impaired. In Caucasian GS patients...

    Authors: Jorge Herrera, Ludwig Amigo, Constanze Husche, Carlos Benítez, Silvana Zanlungo, Dieter Lütjohann, Juan Francisco Miquel and Flavio Nervi

    Citation: Lipids in Health and Disease 2009 8:53

    Content type: Research

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  2. Genome-wide association studies have identified numerous single nucleotide polymorphisms (SNPs) affecting high density lipoprotein (HDL) or low density lipoprotein (LDL) cholesterol levels; these SNPs may cont...

    Authors: James Ronald, Ramakrishnan Rajagopalan, Jane E Ranchalis, Julieann K Marshall, Thomas S Hatsukami, Patrick J Heagerty and Gail P Jarvik

    Citation: Lipids in Health and Disease 2009 8:52

    Content type: Research

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  3. CETP is a plasma protein that modulates atherosclerosis risk through its HDL-cholesterol reducing action. The aim of this work was to examine the effect of the PPARα agonist, ciprofibrate, on the CETP gene exp...

    Authors: Eliete JB Bighetti, Patrícia R Patrício, Andrea C Casquero, Jairo A Berti and Helena CF Oliveira

    Citation: Lipids in Health and Disease 2009 8:50

    Content type: Research

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  4. Detergents are often used to isolate proteins, lipids as well as "detergent-resistant membrane domains" (DRMs) from cells. Different detergents affect different membrane structures according to their physico-c...

    Authors: Ulrike Jakop, Beate Fuchs, Rosmarie Süß, Gudrun Wibbelt, Beate Braun, Karin Müller and Jürgen Schiller

    Citation: Lipids in Health and Disease 2009 8:49

    Content type: Research

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  5. The aim of the study was to evaluate the association of immunoglobulin G type of autoantibodies to oxidized low-density lipoprotein (oxLDL-lgG) and oxLDL-lgM with the progression of esophageal squamous cell ca...

    Authors: Yutao Diao, Hao Li, Huiqing Li, Yingzhi Zhou, Qing Ma, Yan Wang and Dong Li

    Citation: Lipids in Health and Disease 2009 8:48

    Content type: Research

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  6. Citation: Lipids in Health and Disease 2009 8:47

    Content type: Erratum

    Published on:

    The original article was published in Lipids in Health and Disease 2009 8:38

  7. Amyloid-β is recognized as the major constituent of senile plaque found in subjects with Alzheimer's disease. However, there is increasing evidence that in a physiological context amyloid-β may serve as regula...

    Authors: Susan Galloway, Ryusuke Takechi, Menuka MS Pallebage-Gamarallage, Satvinder S Dhaliwal and John CL Mamo

    Citation: Lipids in Health and Disease 2009 8:46

    Content type: Research

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  8. Although consumption of various plant sterol (PS)-enriched beverages is effective in lowering plasma cholesterol, the lipid-lowering potential of PS in a soymilk format has not been investigated thoroughly. Th...

    Authors: Todd C Rideout, Yen-Ming Chan, Scott V Harding and Peter JH Jones

    Citation: Lipids in Health and Disease 2009 8:45

    Content type: Research

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  9. The β2-adrenergic receptor (BAR2) is the main lipolytic receptor in white human adipose tissue. There is a functional glutamine 27 glutamic acid (Gln27Glu, rs 1042714) polymorphism in its gene, which has been var...

    Authors: Tarja Kunnas, Riikka Lahtio, Marja-Leena Kortelainen, Anne Kalela and Seppo T Nikkari

    Citation: Lipids in Health and Disease 2009 8:43

    Content type: Short paper

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  10. Metabolic syndrome is associated with subsequent development of cardiovascular diseases and type 2 diabetes. It is characterized by reduced response to insulin, central obesity, and dyslipidemia. Intake of pla...

    Authors: Ehud Ziv, Natan Patlas, Rony Kalman, Dori Pelled, Yael Herzog, Tali Dror and Tzafra Cohen

    Citation: Lipids in Health and Disease 2009 8:42

    Content type: Research

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  11. Ezetimibe (Zetia®) is a potent inhibitor of cholesterol absorption that has been approved for the treatment of hypercholesterolemia. Statin, an inhibitor of cholesterol synthesis, is the first-choice drug to redu...

    Authors: Minako Yamaoka-Tojo, Taiki Tojo, Rie Kosugi, Yuko Hatakeyama, Yuki Yoshida, Yoji Machida, Naoyoshi Aoyama, Takashi Masuda and Tohru Izumi

    Citation: Lipids in Health and Disease 2009 8:41

    Content type: Research

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  12. There is increasing interest in natural treatments to control dyslipidemia and reduce the risk of cardiovascular disease. Previous studies have demonstrated the beneficial effects of soy yogurt fermented with Ent...

    Authors: Daniela CU Cavallini, Dulcinéia SP Abdalla, Regina C Vendramini, Raquel Bedani, Laura Q Bomdespacho, Nadiége D Pauly-Silveira, Graciela F de Valdez and Elizeu A Rossi

    Citation: Lipids in Health and Disease 2009 8:40

    Content type: Research

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  13. Atherosclerosis which results from gradual deposition of lipids in medium and large arteries is a leading cause of mortality worldwide. The objective of this study was to determine the effect of apple juice on...

    Authors: Mahbubeh Setorki, Sedighe Asgary, Akram Eidi, Ali Haeri rohani and Nafiseh Esmaeil

    Citation: Lipids in Health and Disease 2009 8:39

    Content type: Research

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  14. One of the most important factors in the initiation and progression of atherosclerosis is the default in macrophage cholesterol homeostasis. Many genes and transcription factors such as Peroxisome Proliferator...

    Authors: Javad Zavvar Reza, Mahmoud Doosti, Masoud salehipour, Malehieh PackneJad, Majed Mojarrad, Mansour Heidari and Effat S Emamian

    Citation: Lipids in Health and Disease 2009 8:38

    Content type: Research

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    The Erratum to this article has been published in Lipids in Health and Disease 2009 8:47

  15. Fatty acid composition of serum lipids and adipose tissue triacylglycerols (AT-TAG) partly reflect dietary fatty acid intake. The fatty acid composition is, besides the diet, also influenced by desaturating en...

    Authors: Eva Warensjö, Magdalena Rosell, Mai-Lis Hellenius, Bengt Vessby, Ulf De Faire and Ulf Risérus

    Citation: Lipids in Health and Disease 2009 8:37

    Content type: Short paper

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  16. The purpose of the present investigation was to determine the effects of EPA/DHA supplementation on resting and exercise-induced inflammation and oxidative stress in exercise-trained men. Fourteen men suppleme...

    Authors: Richard J Bloomer, Douglas E Larson, Kelsey H Fisher-Wellman, Andrew J Galpin and Brian K Schilling

    Citation: Lipids in Health and Disease 2009 8:36

    Content type: Research

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  17. Peroxisome proliferator-activated receptor (PPAR)γ is a key regulator in adipose tissue. The rare variant Pro12Ala of PPARγ2 is associated with a decreased risk of insulin resistance. Being dietary PPARγ ligan...

    Authors: J Herrmann, D Rubin, R Häsler, U Helwig, M Pfeuffer, A Auinger, C Laue, P Winkler, S Schreiber, D Bell and J Schrezenmeir

    Citation: Lipids in Health and Disease 2009 8:35

    Content type: Research

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  18. The objective was to investigate in a group of obese subjects the course in skeletal muscle phospholipid (SMPL) fatty acids (FA) during a 24-weeks weight maintenance program, which was preceded by a successful...

    Authors: Steen B Haugaard, Allan Vaag, Huiling Mu and Sten Madsbad

    Citation: Lipids in Health and Disease 2009 8:34

    Content type: Research

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  19. N-3 Polyunsaturated fatty acids have been shown to have potential beneficial effects for chronic diseases including cancer, insulin resistance and cardiovascular disease. Eicosapentaenoic acid (EPA) and docosa...

    Authors: Breanne M Anderson and David WL Ma

    Citation: Lipids in Health and Disease 2009 8:33

    Content type: Review

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  20. We have recently reported that the dietary supplement Meltdown® increases plasma norepinephrine (NE), epinephrine (EPI), glycerol, free fatty acids (FFA), and metabolic rate in men. However, in that investigation...

    Authors: Richard J Bloomer, Robert E Canale, Megan M Blankenship, Kelley G Hammond, Kelsey H Fisher-Wellman and Brian K Schilling

    Citation: Lipids in Health and Disease 2009 8:32

    Content type: Research

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  21. The metabolic syndrome (MetS) is a cluster of metabolic abnormalities comprising visceral obesity, dyslipidaemia and insulin resistance (IR). With the onset of IR, the expression of lipoprotein lipase (LPL), a...

    Authors: Wai Yen Alfred Lim, Yoke Yin Chia, Shih Yeen Liong, So Ha Ton, Khalid Abdul Kadir and Sharifah Noor Akmal Syed Husain

    Citation: Lipids in Health and Disease 2009 8:31

    Content type: Research

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  22. The aim of this work was to assess the effect of chronic administration of protonated nanostructured aluminosilicate (NSAS) on the plasma cholesterol levels and development of atherosclerotic lesions in Apolip...

    Authors: Olena Sivak, Jerry Darlington, Pavel Gershkovich, Panayiotis P Constantinides and Kishor M Wasan

    Citation: Lipids in Health and Disease 2009 8:30

    Content type: Research

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  23. Changes in lipid profile have long been associated with malignancies as lipids play a key role in maintenance of cell integrity. This study evaluated the alterations in extended lipid profile in untreated pati...

    Authors: Ravi Mehrotra, Shruti Pandya, Ajay Kumar Chaudhary, Himanshu Pratap Singh, Ritesh Kumar Jaiswal, Mangal Singh, SC Gupta and Mamta Singh

    Citation: Lipids in Health and Disease 2009 8:29

    Content type: Research

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  24. The metabolism of dietary fatty acids in human has been measured so far using human blood cells and stable-isotope labeled fatty acids, however, no direct data was available for human peripheral tissues and ot...

    Authors: Satoshi Yoshida, Qin-Zeng Zhang, Shu Sakuyama and Satoshi Matsushima

    Citation: Lipids in Health and Disease 2009 8:28

    Content type: Research

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  25. Low-density lipoprotein (LDL) cholesterol lowering is a primary goal in clinical management of patients with cardiovascular disease, but traditional cholesterol levels may not accurately reflect the true ather...

    Authors: David J Decewicz, David M Neatrour, Amy Burke, Mary Jane Haberkorn, Heather L Patney, Marina N Vernalis and Darrell L Ellsworth

    Citation: Lipids in Health and Disease 2009 8:26

    Content type: Research

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  26. Chronic inflammation is a key player in pathogenesis. The inflammatory cytokine, tumor necrosis factor-alpha is a well known inflammatory protein, and has been a therapeutic target for the treatment of disease...

    Authors: Evros K Vassiliou, Andres Gonzalez, Carlos Garcia, James H Tadros, Goutam Chakraborty and Jeffrey H Toney

    Citation: Lipids in Health and Disease 2009 8:25

    Content type: Research

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  27. This study assessed the gender-specific influence of the cholesteryl ester transfer protein (TaqIB, I405V) and lipoprotein lipase (S447X) polymorphisms on the response to an oral fat tolerance test in heterozygot...

    Authors: Katherine K Anagnostopoulou, Genovefa D Kolovou, Peggy M Kostakou, Constantinos Mihas, Georgios Hatzigeorgiou, Christina Marvaki, Dimitrios Degiannis, Dimitri P Mikhailidis and Dennis V Cokkinos

    Citation: Lipids in Health and Disease 2009 8:24

    Content type: Review

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  28. Linoleic 18:2 (n-6) and α-linolenic 18:3 (n-3) essential fatty acids and long-chain polyunsaturated fatty acids (LC-PUFA) are essential nutrients for growth and neonatal development. Consumption of preformed n...

    Authors: Sandra M Barboza Tinoco, Rosely Sichieri, Cecília L Setta, Anibal S Moura and Maria G Tavares do Carmo

    Citation: Lipids in Health and Disease 2009 8:23

    Content type: Research

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  29. Conjugated linoleic acid (CLA) has diverse influences on the immune response in different experimental models. In the present study we investigated the effect of CLA feeding on inflammatory and immune response...

    Authors: Tomaz Malovrh, Lidija Kompan, Polona Juntes, Branka Wraber, Alenka Spindler-Vesel and Drago Kompan

    Citation: Lipids in Health and Disease 2009 8:22

    Content type: Research

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  30. Lactic acid bacteria (LAB) are beneficial probiotic organisms that contribute to improved nutrition, microbial balance, and immuno-enhancement of the intestinal tract, as well as lower cholesterol. Although pr...

    Authors: Do Kyung Lee, Seok Jang, Eun Hye Baek, Mi Jin Kim, Kyung Soon Lee, Hea Soon Shin, Myung Jun Chung, Jin Eung Kim, Kang Oh Lee and Nam Joo Ha

    Citation: Lipids in Health and Disease 2009 8:21

    Content type: Research

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  31. The supply of long-chain polyunsaturated fatty acids via the placenta is interrupted in premature infants, making them exclusively dependent on breast milk, which varies in fatty acid (FA) concentrations depen...

    Authors: Karl-Göran Sabel, Cristina Lundqvist-Persson, Elsa Bona, Max Petzold and Birgitta Strandvik

    Citation: Lipids in Health and Disease 2009 8:20

    Content type: Research

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  32. Lipoprotein-associated phospholipase A2 (Lp-PLA2) also known as serum platelet activating factor acetylhydrolase (PAF-AH) activity constitutes a novel risk marker for cardiovascular disease. Leukocytes constitute...

    Authors: Paraskevi Detopoulou, Tzortzis Nomikos, Elizabeth Fragopoulou, Demosthenis B Panagiotakos, Christos Pitsavos, Christodoulos Stefanadis and Smaragdi Antonopoulou

    Citation: Lipids in Health and Disease 2009 8:19

    Content type: Research

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  33. We have previously shown that dietary red palm oil (RPO) supplementation improves functional recovery in hearts subjected to ischaemia/reperfusion-induced injury. Unfortunately, the cellular and molecular mech...

    Authors: Anna-Mart Engelbrecht, Louise Odendaal, Eugene F Du Toit, Kristina Kupai, Tamás Csont, Peter Ferdinandy and Jacques van Rooyen

    Citation: Lipids in Health and Disease 2009 8:18

    Content type: Research

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  34. Studies in patients with low HDL have suggested that impaired cellular cholesterol efflux is a heritable phenotype increasing atherosclerosis risk. Less is known about the association of macrophage cholesterol...

    Authors: Patrick Linsel-Nitschke, Henning Jansen, Zouhair Aherrarhou, Stefanie Belz, Björn Mayer, Wolfgang Lieb, Fritz Huber, Werner Kremer, Hans-Robert Kalbitzer, Jeanette Erdmann and Heribert Schunkert

    Citation: Lipids in Health and Disease 2009 8:14

    Content type: Research

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  35. Obesity and its complications lead to vascular injury, atherosclerosis, diabetes and pathological angiogenesis. One of the models to study the obesity and its entanglements is the New Zealand Obese mice model....

    Authors: Adriana Balwierz, Anna Polus, Urszula Razny, Lukasz Wator, Grzegorz Dyduch, Romana Tomaszewska, Stephan Scherneck, Hans Joost and Aldona Dembinska-Kiec

    Citation: Lipids in Health and Disease 2009 8:13

    Content type: Research

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  36. There is a predominance of small and dense LDL cholesterol particles in familial combined hyperlipidemia (FCH). The lipoprotein lipase gene could exert an influence in these circumstances.

    Authors: Antonio López-Ruiz, María M Jarabo, María L Martínez-Triguero, Maria Morales-Suárez-Varela, Eva Solá, Celia Bañuls, Marta Casado and Antonio Hernández-Mijares

    Citation: Lipids in Health and Disease 2009 8:12

    Content type: Short paper

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  37. Dietary fatty acids may modulate inflammation in macrophages of the atherosclerotic plaque, affecting its stability. The n-6 polyunsaturated fatty acid (PUFA) arachidonic acid (AA) generally promotes inflammat...

    Authors: Tiina Solakivi, Tarja Kunnas, Satu Kärkkäinen, Olli Jaakkola and Seppo T Nikkari

    Citation: Lipids in Health and Disease 2009 8:11

    Content type: Short paper

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  38. Hypercholesterolemia is one of the most important factors causing cardiovascular disease (CVD). The aim of the present work was to evaluate the relationships between socio-demographic, clinical, lifestyle and ...

    Authors: Stefanos Tyrovolas, Christos Lionis, Akis Zeimbekis, Vassiliki Bountziouka, Mary Micheli, Alexia Katsarou, Natassa Papairakleous, George Metallinos, Kornilia Makri, Evangelos Polychronopoulos and Demosthenes B Panagiotakos

    Citation: Lipids in Health and Disease 2009 8:10

    Content type: Research

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  39. Omega 3 fatty acids have been found to inhibit proliferation, induce apoptosis, and promote differentiation in various cell types. The processes of cell survival, expansion, and differentiation are of key impo...

    Authors: Melinda E Varney, W Elaine Hardman and Vincent E Sollars

    Citation: Lipids in Health and Disease 2009 8:9

    Content type: Research

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  40. Gamma-linolenic acid is a known inhibitor of tumour cell proliferation and migration in both in vitro and in vivo conditions. The aim of the present study was to determine the mechanisms by which gamma-linolenic ...

    Authors: Juliano Andreoli Miyake, Marcel Benadiba and Alison Colquhoun

    Citation: Lipids in Health and Disease 2009 8:8

    Content type: Research

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  41. A recent in vitro study indicates that IGOB131, a novel seed extract of the traditional West African food plant Irvingia gabonensis, favorably impacts adipogenesis through a variety of critical metabolic pathways...

    Authors: Judith L Ngondi, Blanche C Etoundi, Christine B Nyangono, Carl MF Mbofung and Julius E Oben

    Citation: Lipids in Health and Disease 2009 8:7

    Content type: Research

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  42. The aim of the study is to prepare aqueous dispersions of lipid nanoparticles – flurbiprofen solid lipid nanoparticles (FLUSLN) and flurbiprofen nanostructured lipid carriers (FLUNLC) by hot homogenization fol...

    Authors: Kesavan Bhaskar, Jayaraman Anbu, Velayutham Ravichandiran, Vobalaboina Venkateswarlu and Yamsani Madhusudan Rao

    Citation: Lipids in Health and Disease 2009 8:6

    Content type: Research

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  43. Cognitive deficits are a hallmark feature of both Down Syndrome (DS) and Alzheimer's Disease (AD). Extra copies of the genes on chromosome 21 may also play an important role in the accelerated onset of AD in D...

    Authors: Pamela F Parkinson, Timal S Kannangara, Brennan D Eadie, Braydon L Burgess, Cheryl L Wellington and Brian R Christie

    Citation: Lipids in Health and Disease 2009 8:5

    Content type: Research

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  44. The secreted enzyme autotaxin (ATX) stimulates tumor cell migration, tumorigenesis, angiogenesis, and metastasis. ATX hydrolyzes nucleotides, but its hydrolysis of lysophospholipids to produce lysophosphatidic...

    Authors: Eunjin Koh, Russell W Bandle, David D Roberts, Mary L Stracke and Timothy Clair

    Citation: Lipids in Health and Disease 2009 8:4

    Content type: Research

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