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  1. Nitric oxide is a key molecule not only in the cardiovascular system, but also in the metabolic-endocrine system. The purpose of this study was to examine possible associations of the NOS3 T-786C polymorphism (rs...

    Authors: Takahiro Higashibata, Nobuyuki Hamajima, Mariko Naito, Sayo Kawai, Guang Yin, Sadao Suzuki, Yoshikuni Kita, Hideshi Niimura, Takeshi Imaizumi, Keizo Ohnaka, Kokichi Arisawa, Masako Shigeta, Hidemi Ito, Haruo Mikami, Michiaki Kubo, Hideo Tanaka…
    Citation: Lipids in Health and Disease 2012 11:150
    Content type: Research Published on:

  2. Atherosclerosis is a major manifestation of the pathophysiology underlying cardiovascular disease. Flaxseed oil (FO) and α-lipoic acid (LA) have been reported to exert potential benefit to cardiovascular syste...

    Authors: Jiqu Xu, Wei Yang, Qianchun Deng, Qingde Huang, Jin’e Yang and Fenghong Huang
    Citation: Lipids in Health and Disease 2012 11:148
    Content type: Research Published on:

  3. Dietary changes are a major factor in determining cardiovascular risk. n-3 polyunsaturated fatty acids modulate the risk factors for metabolic syndrome via multiple mechanisms, including the regulation of the lip...

    Authors: Adil Haimeur, Lionel Ulmann, Virginie Mimouni, Frédérique Guéno, Fabienne Pineau-Vincent, Nadia Meskini and Gérard Tremblin
    Citation: Lipids in Health and Disease 2012 11:147
    Content type: Research Published on:

  4. Hypertriglyceridemia and postprandial hyperlipidemia is thought to play an important role in atherosclerosis, but to select patients at high-risk for cardiovascular diseases is difficult with triglycerides (TG...

    Authors: Tomoki Nagata, Daisuke Sugiyama, Takako Kise, Satomi Tsuji, Hideo Ohira, Itsuko Sato, Mari Yamamoto, Hitomi Kohsaka, Seiji Kawano, Shizuya Yamashita, Yuichi Ishikawa and Yoshio Fujioka
    Citation: Lipids in Health and Disease 2012 11:146
    Content type: Research Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2014 13:68

  5. Lipid metabolism is altered in subjects with liver steatosis. FAS is a key enzyme in de novo lipogenesis and both FAS gene expression and enzymatic activity are primarily regulated by metabolic signals in the liv...

    Authors: Maria Notarnicola, Giovanni Misciagna, Valeria Tutino, Marisa Chiloiro, Alberto Ruben Osella, Vito Guerra, Caterina Bonfiglio and Maria Gabriella Caruso
    Citation: Lipids in Health and Disease 2012 11:145
    Content type: Research Published on:

  7. Omega-3 fatty acids are important in treatment of severe primary hypertriglyceridemia (HTG). In 15 patients with severe primary HTG (TG >500 mg/dl despite conventional TG lowering therapy), we assessed efficac...

    Authors: Charles J Glueck, Naseer Khan, Muhammad Riaz, Jagjit Padda, Zia Khan and Ping Wang
    Citation: Lipids in Health and Disease 2012 11:143
    Content type: Research Published on:

  8. Polyunsaturated fatty acids are popular dietary supplements advertised to contribute to weight loss by increasing fat metabolism in liver, but the effects on overall muscle metabolism are less established. We ...

    Authors: Roger A Vaughan, Randi Garcia-Smith, Marco Bisoffi, Carole A Conn and Kristina A Trujillo
    Citation: Lipids in Health and Disease 2012 11:142
    Content type: Research Published on:

  9. The association of rs3757354 single nucleotide polymorphism (SNP) in the E3 ubiquitin ligase myosin regulatory light chain-interacting protein (MYLIP, also known as IDOL) gene and serum lipid levels is not wel...

    Authors: Ting-Ting Yan, Rui-Xing Yin, Qing Li, Ping Huang, Xiao-Na Zeng, Ke-Ke Huang, Dong-Feng Wu and Lynn Htet Htet Aung
    Citation: Lipids in Health and Disease 2012 11:141
    Content type: Research Published on:

  11. Atherosclerosis is a chronic degenerative disease of the arteries and is thought to be one of the most common causes of death globally. In recent years, the functions of adventitial fibroblasts in the developm...

    Authors: Jun Wang, Yanfang Si, Chen Wu, Lu Sun, Yudong Ma, Aili Ge and Baomin Li
    Citation: Lipids in Health and Disease 2012 11:139
    Content type: Research Published on:

  12. Type 2 diabetes mellitus (T2DM) is a chronic disease that is characterized by insulin resistance. Its development is directly connected with the inability of insulin to exert its action, not just on carbohydra...

    Authors: Carla Ribeiro, Lucieli Teresa Cambri, Rodrigo Augusto Dalia, Michel Barbosa de Araújo, José Diego Botezelli, Amanda Christine da Silva Sponton and Maria Alice Rostom de Mello
    Citation: Lipids in Health and Disease 2012 11:138
    Content type: Research Published on:

  13. Partly because of functional genomics, there has been a major paradigm shift from solely thinking of skeletal muscle as contractile machinery to an understanding that it can have roles in paracrine and endocri...

    Authors: Theodore W Zderic and Marc T Hamilton
    Citation: Lipids in Health and Disease 2012 11:137
    Content type: Research Published on:

  14. Surgery is the mainstay therapy for HPV-induced laryngeal papillomatosis (LP) and adjuvant therapies are palliative at best. Research revealed that conjugated-linoleic acid (CLA) may improve the outcome of vir...

    Authors: Louise Louw
    Citation: Lipids in Health and Disease 2012 11:136
    Content type: Research Published on:

  15. Cardiomyocytes apoptosis is an important contributor to myocardial dysfunction and heart failure. Adiponectin has cardioprotective effects, potential mechanisms behind it are not clear in cardiomyocytes. The p...

    Authors: Chuan Dong Wei, Yan Li, Hong Yun Zheng, Kai Sheng Sun, Yong Qing Tong, Wen Dai, Wei Wu and An Yu Bao
    Citation: Lipids in Health and Disease 2012 11:135
    Content type: Research Published on:

  16. The aim of the present study was to evaluate the protective effect of concurrent exercise in the degree of the insulin resistance in mice fed with a high-fat diet, and assess adiponectin receptors (ADIPOR1 and...

    Authors: JM Farias, RM Maggi, CB Tromm, LA Silva, TF Luciano, SO Marques, FS Lira, CT de Souza and RA Pinho
    Citation: Lipids in Health and Disease 2012 11:134
    Content type: Research Published on:

  17. Much attention has been drawn to the deleterious effects of adding progestins to estrogen as hormone therapy (HT) in postmenopausal women. Some widely prescribed progestins have been shown to partially oppose ...

    Authors: Gislaine Casanova and Poli Mara Spritzer
    Citation: Lipids in Health and Disease 2012 11:133
    Content type: Research Published on:

  18. Atherogenic dyslipidemia (AD), defined as low HDL-C plus elevated triglycerides (TG), comorbid to T2DM, increases cardiometabolic risk for CAD even when LDL-C is at target. In T2DM males, AD was shown to corre...

    Authors: Michel P Hermans, Sylvie A Ahn and Michel F Rousseau
    Citation: Lipids in Health and Disease 2012 11:132
    Content type: Research Published on:

  19. Obesity is reaching epidemic worldwide and is risk factor for cardiovascular disease and type 2 diabetes. Although plasma high density lipoprotein (HDL) and apolipoprotein A-I (apoA-I) are inversely correlated...

    Authors: Shuai Wang and Daoquan Peng
    Citation: Lipids in Health and Disease 2012 11:131
    Content type: Review Published on:

  20. Cholesteryl ester transfer protein (CETP) plays a major role in lipid metabolism, but studies on the association of CETP polymorphisms with risks of cardiovascular disease are inconsistent. This study investig...

    Authors: Eliane Soler Parra, Natália Baratella Panzoldo, Denise Kaplan, Helena Coutinho Franco de Oliveira, José Ernesto dos Santos, Luiz Sérgio Fernandes de Carvalho, Andrei Carvalho Sposito, Magnus Gidlund, Ruy Tsutomu Nakamura, Vanessa Helena de Souza Zago, Edna Regina Nakandakare, Eder Carlos Rocha Quintão and Eliana Cotta de Faria
    Citation: Lipids in Health and Disease 2012 11:130
    Content type: Short report Published on:

  21. Flaxseed has recently gained attention in the area of cardiovascular disease primarily because of its rich contents of α-linolenic acid (ALA), lignans, and fiber. Although the benefits of exercise on any singl...

    Authors: Howaida A Nounou, Maha M Deif and Manal A Shalaby
    Citation: Lipids in Health and Disease 2012 11:129
    Content type: Research Published on:

  22. Lipoprotein (a) (Lp [a]) is known being correlated with coronary artery disease (CAD). The SLC22A3-LPAL2-LPA gene cluster, relating with modulating the level of plasma Lp (a), has recently been reported to be ass...

    Authors: Xiaofei Lv, Yuan Zhang, Shaoqi Rao, Fengqiong Liu, Xiaoyu Zuo, Dongfang Su, Min Wang, Min Xia, Honghui Guo, Dan Feng, Changjiang Hong, Dan Li, Wenjun Ma, Ping Ouyang, Xinrui Li, Xiang Feng…
    Citation: Lipids in Health and Disease 2012 11:128
    Content type: Research Published on:

  23. A dietary supplement containing a blend of 170 mg of N-oleyl-phosphatidylethanolamine (NOPE) and 100 mg of epigallocatechin-3-gallate (EGCG) has been shown to improve compliance to low caloric diets. Consideri...

    Authors: Gerald T Mangine, Adam M Gonzalez, Adam J Wells, William P McCormack, Maren S Fragala, Jeffrey R Stout and Jay R Hoffman
    Citation: Lipids in Health and Disease 2012 11:127
    Content type: Research Published on:

  24. The objective of the study is a comparative evaluation of flavone isolated from Mucuna pruriens and coumarin isolated from Ionidium suffruticosum was assessed for the hypolipidemic activity in rats fed with high ...

    Authors: Satheesh Kumar Dharmarajan and Kottai Muthu Arumugam
    Citation: Lipids in Health and Disease 2012 11:126
    Content type: Research Published on:

  25. Visceral fat possesses the most detrimental potential for cardiovascular morbidity through the release of adipokines, as well as metabolic and proinflammatory mediators, which adversely affect metabolic and va...

    Authors: Apostolos Perelas, Vanessa Safarika, Ioannis S Vlachos, Irene Tzanetakou, Laskarina-Maria Korou, Panagiotis Konstantopoulos, Ilias Doulamis, Ioannis Ioannidis, Ioannis Kornezos, Dimitrios Gargas, Christos Klonaris, Despina N Perrea and Achilleas Chatziioannou
    Citation: Lipids in Health and Disease 2012 11:125
    Content type: Short report Published on:

  26. The hydrolysis activities of three alkaline lipases, L-A1, L-A2 and L-A3 secreted by different lipase-producing microorganisms isolated from the Bay of Bohai, P. R. China were characterized with 16 kinds of es...

    Authors: Haikuan Wang, Xiaojie Wang, Xiaolu Li, Yehong Zhang, Yujie Dai, Changlu Guo and Heng Zheng
    Citation: Lipids in Health and Disease 2012 11:124
    Content type: Research Published on:

  27. Although statins (STs) are drugs of first choice in hypercholesterolemic patients, especially in those at high cardiovascular risk, some of them are intolerant to STs or refuse treatment with these drugs. In v...

    Authors: Livia Pisciotta, Antonella Bellocchio and Stefano Bertolini
    Citation: Lipids in Health and Disease 2012 11:123
    Content type: Research Published on:

  28. The effect of an herbal formulation LI85008F on weight loss in obese human subjects was evaluated in an 8-weeks randomized, double-blind, placebo-controlled study (Clinical Trial Registration no. ISRCTN3738170...

    Authors: Krishanu Sengupta, Atmatrana T Mishra, Manikeswar K Rao, Kadainti VS Sarma, Alluri V Krishnaraju and Golakoti Trimurtulu
    Citation: Lipids in Health and Disease 2012 11:122
    Content type: Research Published on:

  29. Periodontal disease is suggested to increase the risk of atherothrombotic disease by inducing dyslipidemia. Recently, we demonstrated that proprotein convertase subtilisin/kexin type 9 (PCSK9), which is known ...

    Authors: Haruna Miyazawa, Koichi Tabeta, Sayuri Miyauchi, Yukari Aoki-Nonaka, Hisanori Domon, Tomoyuki Honda, Takako Nakajima and Kazuhisa Yamazaki
    Citation: Lipids in Health and Disease 2012 11:121
    Content type: Research Published on:

  30. Schisandra, a globally distributed plant, has been widely applied to health care products. Here, we investigated the effects of dietary intake of Fructus Schisandrae chinensis (FSC), both aqueous and ethanolic...

    Authors: Si-Yuan Pan, Qing Yu, Yi Zhang, Xiao-Yan Wang, Nan Sun, Zhi-Ling Yu and Kam-Ming Ko
    Citation: Lipids in Health and Disease 2012 11:120
    Content type: Research Published on:

  31. Advanced stages of leprosy show T cell unresponsiveness and lipids of mycobacterial origin are speculated to modulate immune responses in these patients. Present study elucidates the role of phenolicglycolipid...

    Authors: Pradeep Kumar Dagur, Bhawna Sharma, Rajni Upadhyay, Bhavyata Dua, Arshad Rizvi, Naim Akhtar Khan, Vishwa Mohan Katoch, Utpal Sengupta and Beenu Joshi
    Citation: Lipids in Health and Disease 2012 11:119
    Content type: Research Published on:

  32. The single and combined effects of scavenger receptor-BI (SR-BI), ATP-binding cassette transporter (ABC) A1 and G1 on cholesterol efflux from Chinese Hamster Ovary (CHO) cells were investigated.

    Authors: Guohua Song, Chuanlong Zong, Qian Liu, Yanhong Si, Jie Liu, Wei Li, Ping Zhu and Shucun Qin
    Citation: Lipids in Health and Disease 2012 11:118
    Content type: Research Published on:

  33. Several studies have identified use of non-steroidal-anti-inflammatory drugs and statins for prevention of dementia, but their efficacy in slowing progression is not well understood. Cerebrovascular disturbanc...

    Authors: Menuka Pallebage-Gamarallage, Virginie Lam, Ryusuke Takechi, Susan Galloway, Karin Clark and John Mamo
    Citation: Lipids in Health and Disease 2012 11:117
    Content type: Research Published on:

  34. Omega-3 poly-unsaturated fatty acids (ω-3 PUFAs) have demonstrated to be beneficial in the prevention of cardiovascular disease, however, the mechanisms by which they perform their cardiovascular protection ha...

    Authors: Elena Burillo, Rocío Mateo-Gallego, Ana Cenarro, Sarah Fiddyment, Ana M Bea, Inmaculada Jorge, Jesús Vázquez and Fernando Civeira
    Citation: Lipids in Health and Disease 2012 11:116
    Content type: Research Published on:

  35. Inflammation and increased ceramide concentrations characterise adipose tissue of obese women with high liver fat content compared to equally obese women with normal liver fat content. The present study charac...

    Authors: Maria Kolak, Joanna Gertow, Jukka Westerbacka, Scott A Summers, Jan Liska, Anders Franco-Cereceda, Matej Orešič, Hannele Yki-Järvinen, Per Eriksson and Rachel M Fisher
    Citation: Lipids in Health and Disease 2012 11:115
    Content type: Research Published on:

  36. Previous studies showed that intake of yacon or some lactic acid bacteria was able to inhibit the development of diabetes mellitus, by reducing glucose and associated symptoms, for example, the lipid profile.

    Authors: Mariana N Roselino, Nadiége D Pauly-Silveira, Daniela CU Cavallini, Larissa S Celiberto, Roseli A Pinto, Regina C Vendramini and Elizeu A Rossi
    Citation: Lipids in Health and Disease 2012 11:114
    Content type: Research Published on:

  37. Milk contains numerous nutrients. The content of n-3 fatty acids, the n-6/n-3 ratio, and short- and medium-chain fatty acids may promote positive health effects. In Western societies, cow’s milk fat is perceiv...

    Authors: Giovanni Martemucci and Angela Gabriella D’Alessandro
    Citation: Lipids in Health and Disease 2012 11:113
    Content type: Research Published on:

  38. Fucoxanthin is a xanthophyll present in brown seaweeds and has several beneficial effects, including anti-obesity and anti-diabetic effects. However, we and another group previously observed that fucoxanthin i...

    Authors: Fumiaki Beppu, Masashi Hosokawa, Yoshimi Niwano and Kazuo Miyashita
    Citation: Lipids in Health and Disease 2012 11:112
    Content type: Research Published on:

  39. It is known that the increased level of IDL and oxidized LDL are associated with risk of cardiovascular disease, and the lipoprotein abnormalities accelerate atherosclerosis. Cardiovascular disease is a major ...

    Authors: Yuji Hirowatari, Yasuhiko Homma, Joe Yoshizawa and Koichiro Homma
    Citation: Lipids in Health and Disease 2012 11:111
    Content type: Short report Published on:

  40. The interactions of oxidized low-density lipoprotein (LDL) and macrophages are hallmarks in the development of atherosclerosis. The biological activities of the modified particle in these cells are due to the ...

    Authors: Ute Stemmer, Zsuzsanna A Dunai, Daniel Koller, Gabriel Pürstinger, Elfriede Zenzmaier, Hans P Deigner, Elma Aflaki, Dagmar Kratky and Albin Hermetter
    Citation: Lipids in Health and Disease 2012 11:110
    Content type: Research Published on:

  41. Brain-derived neurotrophic factor (BDNF) is a potent neurotrophic factor that is implicated in the regulation of food intake and body weight. Polyunsaturated fatty acids (PUFAs) localised in cell membranes hav...

    Authors: Umashankar Vetrivel, Sathya Baarathi Ravichandran, Kaviarasan Kuppan, Jithu Mohanlal, Undurti Narasimha Das and Angayarkanni Narayanasamy
    Citation: Lipids in Health and Disease 2012 11:109
    Content type: Research Published on:

  42. Ingestion of glucosylceramide improves transepidermal water loss (TEWL) from the skin, but the underlying mechanism by which a small amount of dietary glucosylceramide can vastly improve skin conditions remain...

    Authors: Yoshiyuki Shirakura, Kanako Kikuchi, Kenji Matsumura, Katsuyuki Mukai, Susumu Mitsutake and Yasuyuki Igarashi
    Citation: Lipids in Health and Disease 2012 11:108
    Content type: Research Published on:

  43. To compare the predictive ability of adolescent lipoprotein classification using the National Examination Survey (NHANES) cut points and those of the National Cholesterol Education Program (NCEP) for predictin...

    Authors: Masumeh Hatami, Maryam Tohidi, Reza Mohebi, Davood Khalili, Fereidoun Azizi and Farzad Hadaegh
    Citation: Lipids in Health and Disease 2012 11:107
    Content type: Research Published on:

  44. Adiponectin is reported to relate with cardiovascular diseases, we sought to examine whether adiponectin is associated with disease progression of heart failure from hypertension in rats in comparison with oth...

    Authors: Mingqiang Fu, Jingmin Zhou, Juying Qian, Xuejuan Jin, Hongmin Zhu, Chunlin Zhong, Michael Fu, Yunzeng Zou and Junbo Ge
    Citation: Lipids in Health and Disease 2012 11:106
    Content type: Research Published on:

  45. Epidemiological studies have suggested the benefits of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on cardiovascular health, but only limited data are available describing n-3 PUFA regulated pathways in hu...

    Authors: Simone Schmidt, Frank Stahl, Kai-Oliver Mutz, Thomas Scheper, Andreas Hahn and Jan P Schuchardt
    Citation: Lipids in Health and Disease 2012 11:105
    Content type: Research Published on:

  46. Since the amounts of arachidonic acid (AA) and EPA in food may have implications for human health, we investigated whether a small change in chicken feed influenced the blood lipid concentration in humans inge...

    Authors: Anna Haug, Nicole F Nyquist, Therese J Mosti, Malin Andersen and Arne T Høstmark
    Citation: Lipids in Health and Disease 2012 11:104
    Content type: Research Published on:

  48. The aim of the present study was to appraise the antimicrobial activity of Ricinus communis L. essential oil against different pathogenic microorganisms and the cytotoxic activity against HeLa cell lines.

    Authors: Zied Zarai, Ines Ben Chobba, Riadh Ben Mansour, Ahmed Békir, Néji Gharsallah and Adel Kadri
    Citation: Lipids in Health and Disease 2012 11:102
    Content type: Research Published on:

  49. Metabolic syndrome (MetS) is an important health problem which puts individuals at risk for cardiovascular diseases and type 2 diabetes as well as obesity-related cancers such as colon and renal cell in men, a...

    Authors: Fareed K N Arthur, Michael Adu-Frimpong, James Osei-Yeboah, Faustina O Mensah and Lawrence Owusu
    Citation: Lipids in Health and Disease 2012 11:101
    Content type: Research Published on:

  50. Although most of what is known about the biology and function of arachidonic acid metabolites comes from the study of mammalian biology, these compounds can also be produced by lower eukaryotes, including yeas...

    Authors: Ruan Ells, Johan LF Kock, Jacobus Albertyn and Carolina H Pohl
    Citation: Lipids in Health and Disease 2012 11:100
    Content type: Review Published on:
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Lipids in Health and Disease

ISSN: 1476-511X