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  1. The interactions of oxidized low-density lipoprotein (LDL) and macrophages are hallmarks in the development of atherosclerosis. The biological activities of the modified particle in these cells are due to the ...

    Authors: Ute Stemmer, Zsuzsanna A Dunai, Daniel Koller, Gabriel Pürstinger, Elfriede Zenzmaier, Hans P Deigner, Elma Aflaki, Dagmar Kratky and Albin Hermetter
    Citation: Lipids in Health and Disease 2012 11:110
    Content type: Research Published on:

  2. Brain-derived neurotrophic factor (BDNF) is a potent neurotrophic factor that is implicated in the regulation of food intake and body weight. Polyunsaturated fatty acids (PUFAs) localised in cell membranes hav...

    Authors: Umashankar Vetrivel, Sathya Baarathi Ravichandran, Kaviarasan Kuppan, Jithu Mohanlal, Undurti Narasimha Das and Angayarkanni Narayanasamy
    Citation: Lipids in Health and Disease 2012 11:109
    Content type: Research Published on:

  3. Ingestion of glucosylceramide improves transepidermal water loss (TEWL) from the skin, but the underlying mechanism by which a small amount of dietary glucosylceramide can vastly improve skin conditions remain...

    Authors: Yoshiyuki Shirakura, Kanako Kikuchi, Kenji Matsumura, Katsuyuki Mukai, Susumu Mitsutake and Yasuyuki Igarashi
    Citation: Lipids in Health and Disease 2012 11:108
    Content type: Research Published on:

  4. To compare the predictive ability of adolescent lipoprotein classification using the National Examination Survey (NHANES) cut points and those of the National Cholesterol Education Program (NCEP) for predictin...

    Authors: Masumeh Hatami, Maryam Tohidi, Reza Mohebi, Davood Khalili, Fereidoun Azizi and Farzad Hadaegh
    Citation: Lipids in Health and Disease 2012 11:107
    Content type: Research Published on:

  5. Adiponectin is reported to relate with cardiovascular diseases, we sought to examine whether adiponectin is associated with disease progression of heart failure from hypertension in rats in comparison with oth...

    Authors: Mingqiang Fu, Jingmin Zhou, Juying Qian, Xuejuan Jin, Hongmin Zhu, Chunlin Zhong, Michael Fu, Yunzeng Zou and Junbo Ge
    Citation: Lipids in Health and Disease 2012 11:106
    Content type: Research Published on:

  6. Epidemiological studies have suggested the benefits of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on cardiovascular health, but only limited data are available describing n-3 PUFA regulated pathways in hu...

    Authors: Simone Schmidt, Frank Stahl, Kai-Oliver Mutz, Thomas Scheper, Andreas Hahn and Jan P Schuchardt
    Citation: Lipids in Health and Disease 2012 11:105
    Content type: Research Published on:

  7. Since the amounts of arachidonic acid (AA) and EPA in food may have implications for human health, we investigated whether a small change in chicken feed influenced the blood lipid concentration in humans inge...

    Authors: Anna Haug, Nicole F Nyquist, Therese J Mosti, Malin Andersen and Arne T Høstmark
    Citation: Lipids in Health and Disease 2012 11:104
    Content type: Research Published on:

  9. The aim of the present study was to appraise the antimicrobial activity of Ricinus communis L. essential oil against different pathogenic microorganisms and the cytotoxic activity against HeLa cell lines.

    Authors: Zied Zarai, Ines Ben Chobba, Riadh Ben Mansour, Ahmed Békir, Néji Gharsallah and Adel Kadri
    Citation: Lipids in Health and Disease 2012 11:102
    Content type: Research Published on:

  10. Metabolic syndrome (MetS) is an important health problem which puts individuals at risk for cardiovascular diseases and type 2 diabetes as well as obesity-related cancers such as colon and renal cell in men, a...

    Authors: Fareed K N Arthur, Michael Adu-Frimpong, James Osei-Yeboah, Faustina O Mensah and Lawrence Owusu
    Citation: Lipids in Health and Disease 2012 11:101
    Content type: Research Published on:

  11. Although most of what is known about the biology and function of arachidonic acid metabolites comes from the study of mammalian biology, these compounds can also be produced by lower eukaryotes, including yeas...

    Authors: Ruan Ells, Johan LF Kock, Jacobus Albertyn and Carolina H Pohl
    Citation: Lipids in Health and Disease 2012 11:100
    Content type: Review Published on:

  12. The purpose of the present study was to evaluate the relationship between sleep duration and dietary habits in elderly obese patients treated at an institute of cardiology.

    Authors: Aline Alves Santana, Gustavo Duarte Pimentel, Monica Romualdo, Lila Missae Oyama, Ronaldo Vagner Thomatieli Santos, Ricardo Aurino Pinho, Claudio Teodoro de Souza, Bruno Rodrigues, Erico Chagas Caperuto and Fabio Santos Lira
    Citation: Lipids in Health and Disease 2012 11:99
    Content type: Research Published on:

  13. Pentacyclic triterpenes in general exert beneficial effects in metabolic disorders. This study investigated the effects of α, β-amyrin, a pentacyclic triterpene mixture from the resin of Protium heptaphyllum on b...

    Authors: Flávia Almeida Santos, Julyanne Torres Frota, Bruno Rodrigues Arruda, Tiago Sousa de Melo, Armenio André de Carvalho Almeida da Silva, Gerly Anne de Castro Brito, Mariana Helena Chaves and Vietla Satyanarayana Rao
    Citation: Lipids in Health and Disease 2012 11:98
    Content type: Short report Published on:

  14. Several genetic polymorphisms have been reported to modify the effects of smoking on serum lipid levels. The objective of this study was to investigate whether longevity-associated mitochondrial DNA 5178 (Mt51...

    Authors: Akatsuki Kokaze, Mamoru Ishikawa, Naomi Matsunaga, Kanae Karita, Masao Yoshida, Naoki Shimada, Tadahiro Ohtsu, Takako Shirasawa, Hirotaka Ochiai, Masao Satoh, Masayasu Hashimoto, Hiromi Hoshino and Yutaka Takashima
    Citation: Lipids in Health and Disease 2012 11:97
    Content type: Research Published on:

  15. Stem/progenitor cell-based therapy has successfully been used as a novel therapeutic strategy for vascular diseases triggered by endothelial dysfunction. The aim of this study was to investigate the effects of...

    Authors: Leandro C F Lima, Marcella L Porto, Bianca P Campagnaro, Clarissa L Tonini, Breno V Nogueira, Thiago MC Pereira, Elisardo C Vasquez and Silvana S Meyrelles
    Citation: Lipids in Health and Disease 2012 11:96
    Content type: Research Published on:

  16. Saury oil contains considerable amounts of n-3 polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) with long aliphatic tails (>18C atoms). Ingestion of saury oil reduces the risk of devel...

    Authors: Zhi-Hong Yang, Hiroko Miyahara, Jiro Takeo and Masashi Katayama
    Citation: Lipids in Health and Disease 2012 11:95
    Content type: Short report Published on:

    The Erratum to this article has been published in Lipids in Health and Disease 2012 11:151

  17. Cigarette smoking had been confirmed as an increased risk for dyslipidemia, but none of the evidence was from long-lived population. In present study, we detected relationship between cigarette smoking habits ...

    Authors: Zhang Yan-Ling, Zhao Dong-Qing, Huang Chang-Quan and Dong Bi-Rong
    Citation: Lipids in Health and Disease 2012 11:94
    Content type: Research Published on:

  18. This study aimed at investigating the oxidative stress ameliorating effect, lipids profile restoration, and the anti-inflammatory effect of Samsum Ant Venom (SAV) in induced endotoxemic male rats, injected wit...

    Authors: Hossam Ebaid, Mohamed Al-Khalifa, Ahmed M Isa and Saad Gadoa
    Citation: Lipids in Health and Disease 2012 11:93
    Content type: Research Published on:

  20. The relationships between fat mass and bone tissue are complex and not fully elucidated. A high-fat/high-sucrose diet has been shown to induce harmful effects on bone micro architecture and bone biomechanics o...

    Authors: Maude Gerbaix, Lore Metz, Fabrice Mac-Way, Cédric Lavet, Christelle Guillet, Stéphane Walrand, Aurélie Masgrau, Marie-Thérèse Linossier, Laurence Vico and Daniel Courteix
    Citation: Lipids in Health and Disease 2012 11:91
    Content type: Research Published on:

  21. Diabetic retinopathy is a major complication of dysregulated hyperglycemia. Retinal vascular endothelial cell dysfunction is an early event in the pathogenesis of diabetic retinopathy. Studies showed that hype...

    Authors: Junhui Shen, Shengrong Shen, Undurti N Das and Guotong Xu
    Citation: Lipids in Health and Disease 2012 11:90
    Content type: Research Published on:

  22. Tangier disease (TD) is a phenotypic expression of rare familial syndrome with mutations in the ABCA1 transporter. The risk of coronary artery disease in patients with TD is variable. On the other hand the piv...

    Authors: Vana Kolovou, Vasiliki D Papakonstantinou, George Stamatakis, Sophia N Verouti, Marianna N Xanthopoulou, Genovefa Kolovou and Constantinos A Demopoulos
    Citation: Lipids in Health and Disease 2012 11:89
    Content type: Research Published on:

  23. The erythrocyte membrane lesion is a serious diabetic complication. A number of studies suggested that n-3 fatty acid could reduce lipid peroxidation and elevate α- or γ-tocopherol contents in membrane of eryt...

    Authors: Wei Yang, Juan Fu, Miao Yu, Qingde Huang, Di Wang, Jiqu Xu, Qianchun Deng, Ping Yao, Fenghong Huang and Liegang Liu
    Citation: Lipids in Health and Disease 2012 11:88
    Content type: Research Published on:

  24. Fluorescence-based cell-free assays offer an attractive alternative to current cell-based assays for measuring the redox activity of High-Density Lipoprotein (HDL). We have recently developed a biochemical ass...

    Authors: Theodoros Kelesidis, Srinivasa T Reddy, Diana Huynh, David Meriwether, Alan M Fogelman, Mohamad Navab and Otto O Yang
    Citation: Lipids in Health and Disease 2012 11:87
    Content type: Research Published on:

  25. The study was undertaken to examine the effects of berberine (BBR) on serum homocysteine, lipids and the aortic lesion in Sprague–Dawley (SD) rats fed with a long-term high-fat diet (HFD).

    Authors: Xin-xia Chang, Hong-mei Yan, Qiong Xu, Ming-feng Xia, Hua Bian, Teng-fang Zhu and Xin Gao
    Citation: Lipids in Health and Disease 2012 11:86
    Content type: Research Published on:

  26. Oxidized low density lipoprotein (ox-LDL), a risk factor of atherosclerosis, facilitates the formation and vulnerability of atherosclerotic plaque, thus contributing to several clinical complications. Stem cel...

    Authors: Hui Yang, Ahmed Salah Salem Mohamed and Sheng-hua Zhou
    Citation: Lipids in Health and Disease 2012 11:85
    Content type: Review Published on:

  27. The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited source of new active substances in the field of the development of bioactive products. In our...

    Authors: Yosra Ayed, Manel Bousabbeh, Hazem Ben Mabrouk, Maram Morjen, Naziha Marrakchi and Hassen Bacha
    Citation: Lipids in Health and Disease 2012 11:84
    Content type: Research Published on:

  28. A recent study investigated the MYLIP region in the Mexican population in order to fine-map the actual susceptibility variants of this locus. The p.N342S polymorphism was identified as the underlying functional v...

    Authors: Paulo C J L Santos, Theo G M Oliveira, Pedro A Lemos, José G Mill, José E Krieger and Alexandre C Pereira
    Citation: Lipids in Health and Disease 2012 11:83
    Content type: Research Published on:

  29. Excess peroxisome proliferator-activated receptor (PPAR) stimulation has been associated with detrimental health effects including impaired myocardial function. Recently, supplementation with n-3 polyunsaturat...

    Authors: Elin Strand, Bodil Bjorndal, Ottar Nygard, Lena Burri, Christ Berge, Pavol Bohov, Bjørn J Christensen, Kjetil Berge, Hege Wergedahl, Asgaut Viste and Rolf K Berge
    Citation: Lipids in Health and Disease 2012 11:82
    Content type: Research Published on:

  30. Rose-scented geranium (Pelargonium graveolens L’Hér.), which is used in traditional Tunisian folk medicine for the treatment of hyperglycaemia, is widely known as one of the medicinal herbs with the highest antio...

    Authors: Maher Boukhris, Mohamed Bouaziz, Ines Feki, Hedya Jemai, Abdelfattah El Feki and Sami Sayadi
    Citation: Lipids in Health and Disease 2012 11:81
    Content type: Research Published on:

  31. A sedentary lifestyle predisposes to cardiometabolic diseases. Lifestyle changes such as increased physical activity improve a range of cardiometabolic risk factors. The objective of this study was to examine ...

    Authors: Per Sjögren, Justo Sierra-Johnson, Lena V Kallings, Tommy Cederholm, Maria Kolak, Mats Halldin, Kerstin Brismar, Ulf de Faire, Mai-Lis Hellénius and Rachel M Fisher
    Citation: Lipids in Health and Disease 2012 11:80
    Content type: Research Published on:

  32. There is a relationship among hypercholesterolemia, oxidative stress and inflammation in the atherogenesis. Thus, the objective of the present study was to assess paraoxonase (PON1), superoxide dismutase (SOD)...

    Authors: Paula Rossini Augusti, Amanda Roggia Ruviaro, Andréia Quatrin, Sabrina Somacal, Greicy Michelle Marafiga Conterato, Juliana Tanara Vicentini, Marta Medeiros Frescura Duarte and Tatiana Emanuelli
    Citation: Lipids in Health and Disease 2012 11:79
    Content type: Research Published on:

  33. The main purpose of this research was to investigate the alterations in the aerobic capacity and appearance of metabolic alterations in Wistar rats fed on fructose-rich diet. We separated twenty-eight rats int...

    Authors: José Diego Botezelli, Lucieli Teresa Cambri, Ana Carolina Ghezzi, Rodrigo Augusto Dalia, Fabrício Azevedo Voltarelli and Maria Alice Rostom de Mello
    Citation: Lipids in Health and Disease 2012 11:78
    Content type: Research Published on:

  34. Cardiovascular disease (CVD) is the number one cause of mortality worldwide and a low high-density lipoprotein cholesterol (HDL-C) level is an important marker of CVD risk. Garlic (Allium sativum) has been widely...

    Authors: Seohyun Lee, Hyunjin Joo, Chong-Tai Kim, In-Hwan Kim and Yangha Kim
    Citation: Lipids in Health and Disease 2012 11:77
    Content type: Research Published on:

  35. Altered immune function during ageing results in increased production of nitric oxide (NO) and other inflammatory mediators. Recently, we have reported that NO production was inhibited by naturally-occurring p...

    Authors: Asaf A Qureshi, Xiu Qin Guan, Julia C Reis, Christopher J Papasian, Sandra Jabre, David C Morrison and Nilofer Qureshi
    Citation: Lipids in Health and Disease 2012 11:76
    Content type: Research Published on:

  36. Resynthesis of triglycerides in enterocytes of the small intestine plays a critical role in the absorption of dietary fat. Acyl-CoA:monoacylglycerol acyltransferase-2 (MGAT2) is highly expressed in the small i...

    Authors: Takuma Tsuchida, Sayaka Fukuda, Hisanori Aoyama, Nobuhiko Taniuchi, Tomomi Ishihara, Noriko Ohashi, Hiroko Sato, Koji Wakimoto, Masaharu Shiotani and Akira Oku
    Citation: Lipids in Health and Disease 2012 11:75
    Content type: Research Published on:

  38. We describe a system for the automated diagnosis of diabetic retinopathy and glaucoma using fundus and optical coherence tomography (OCT) images. Automatic screening will help the doctors to quickly identify t...

    Authors: Arulmozhivarman Pachiyappan, Undurti N Das, Tatavarti VSP Murthy and Rao Tatavarti
    Citation: Lipids in Health and Disease 2012 11:73
    Content type: Research Published on:

  39. The present work aims at preparing aqueous suspension of Solid lipid Nanoparticles containing Chitosan (CT) which is a biopolymer that exhibits a number of interesting properties which include controlled drug ...

    Authors: Rahul Nair, Ashok CK Kumar, Vishnu K Priya, Chakrapani M Yadav and Prasanna Y Raju
    Citation: Lipids in Health and Disease 2012 11:72
    Content type: Research Published on:

  40. The health benefits of omega-3 and omega-6 polyunsaturated fatty acids (PUFA) are generally recognized. Unfortunately, in most Mediterranean countries, the recommended daily intake of these compounds is rarely...

    Authors: Imen Fendri, Lamia Khannous, Zouhir Mallek, Al Ibrahim Traore, Néji Gharsallah and Radhouane Gdoura
    Citation: Lipids in Health and Disease 2012 11:71
    Content type: Research Published on:

  41. Bioactivities of Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) depend on their chemical forms. The present study was to investigate short term effects of triglyceride (TG), ethyl ester (EE), free ...

    Authors: Xiao Tang, Zhao-Jie Li, Jie Xu, Yong Xue, Jin-Zhang Li, Jing-Feng Wang, Teruyoshi Yanagita, Chang-Hu Xue and Yu-Ming Wang
    Citation: Lipids in Health and Disease 2012 11:70
    Content type: Research Published on:

  42. Retinoic acids regulate the reverse cholesterol transport by inducing the ATP binding cassette transporter A1 (ABCA1) dependent cholesterol efflux in macrophages, neuronal as well as intestine cells. In the pr...

    Authors: Hong Jiang, Yunden Badralmaa, Jun Yang, Richard Lempicki, Allison Hazen and Ven Natarajan
    Citation: Lipids in Health and Disease 2012 11:69
    Content type: Research Published on:

  43. The effects of exposure to a 50 Hz electric field (EF) on plasma level of triacylglycerol, free fatty acids, total cholesterol and phospholipid and mRNA expression level of diacylglycerol acyltransferase (DGAT...

    Authors: Takuya Hori, Shinji Harakawa, Shirley M Herbas, Yoshiko Y Ueta, Noboru Inoue and Hiroshi Suzuki
    Citation: Lipids in Health and Disease 2012 11:68
    Content type: Research Published on:

  44. Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated dise...

    Authors: Gabriela TD Sousa, Fábio S Lira, José C Rosa, Erick P de Oliveira, Lila M Oyama, Ronaldo V Santos and Gustavo D Pimentel
    Citation: Lipids in Health and Disease 2012 11:67
    Content type: Review Published on:

  45. Hepatic gluconeogenesis tightly controls blood glucose levels in healthy individuals, yet disorders of fatty acids (FAs) oxidation are characterized by hypoglycemia. We studied the ability of free-FAs to direc...

    Authors: Noga Budick-Harmelin, Sarit Anavi, Zecharia Madar and Oren Tirosh
    Citation: Lipids in Health and Disease 2012 11:66
    Content type: Research Published on:

  46. The aim was to investigate new markers for type 2 diabetes (T2DM) dyslipidemia related with LDL and HDL metabolism. Removal from plasma of free and esterified cholesterol transported in LDL and the transfer of...

    Authors: Carolina P Oliveira, Raul C Maranhão, Marina P Bertato, Bernardo L Wajchenberg and Antonio C Lerario
    Citation: Lipids in Health and Disease 2012 11:65
    Content type: Research Published on:

  47. Many of the metabolic effects of exercise are due to the most recent exercise session. With recent advances in nuclear magnetic resonance spectroscopy (NMRS), it is possible to gain insight about which lipopro...

    Authors: Michael Harrison, Niall M Moyna, Theodore W Zderic, Donal J O’Gorman, Noel McCaffrey, Brian P Carson and Marc T Hamilton
    Citation: Lipids in Health and Disease 2012 11:64
    Content type: Research Published on:

  48. Conjugated linoleic acids (CLA) are in focus of dairy cattle research because of its milk fat reducing effects. Little is known about the impact of CLA on immune function in dairy cows. Therefore, in the prese...

    Authors: Lydia Renner, Julia Pappritz, Ronny Kramer, Susanne Kersten, Gerhard Jahreis and Sven Dänicke
    Citation: Lipids in Health and Disease 2012 11:63
    Content type: Research Published on:

  49. One of the important proteins involved in lipid metabolism is the ATP-binding cassette transporter A1 (ABCA1) encoding by ABCA1 gene. In this study we evaluated the single nucleotide polymorphisms (SNPs) of ABCA1...

    Authors: Vana Kolovou, Apostolia Marvaki, Agathi Karakosta, Georgios Vasilopoulos, Antonia Kalogiani, Sophie Mavrogeni, Dimitrios Degiannis, Christina Marvaki and Genovefa Kolovou
    Citation: Lipids in Health and Disease 2012 11:62
    Content type: Research Published on:

  50. Niemann-pick C1-like 1 (NPC1L1) is a key protein for intestinal cholesterol transportation. Common single nucleotide polymorphisms (SNPs) in the NPC1L1 gene have been associated with cholesterol absorption and...

    Authors: Lin Miao, Rui-Xing Yin, Xi-Jiang Hu, Dong-Feng Wu, Xiao-Li Cao, Qing Li, Ting-Ting Yan, Lynn Htet Htet Aung, Jin-Zhen Wu and Wei-Xiong Lin
    Citation: Lipids in Health and Disease 2012 11:61
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X