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  1. Cytoplasmic lipid-droplets are common inclusions of eukaryotic cells. Lipid-droplet binding thalidomide analogs (2,6-dialkylphenyl-4/5-amino-substituted-5,6,7-trifluorophthalimides) with potent anticancer acti...

    Authors: László G Puskás, Liliána Z Fehér, Csaba Vizler, Ferhan Ayaydin, Erzsébet Rásó, Eszter Molnár, István Magyary, Iván Kanizsai, Márió Gyuris, Ramóna Madácsi, Gabriella Fábián, Klaudia Farkas, Péter Hegyi, Ferenc Baska, Béla Ózsvári and Klára Kitajka
    Citation: Lipids in Health and Disease 2010 9:56
    Content type: Research Published on:

  2. This study compared LDL, HDL, and VLDL subclasses in overweight or obese adults consuming either a reduced carbohydrate (RC) or reduced fat (RF) weight maintenance diet for 9 months following significant weigh...

    Authors: James D LeCheminant, Bryan K Smith, Eric C Westman, Mary C Vernon and Joseph E Donnelly
    Citation: Lipids in Health and Disease 2010 9:54
    Content type: Short paper Published on:

  3. Our aim was to evaluate the effects of soybean oil treatment for 15 days on arterial and ventricular pressure, myocardial mechanics and proteins involved in calcium handling.

    Authors: Rogério Faustino Ribeiro Junior, Aurélia Araújo Fernandes, Eduardo Frizzera Meira, Priscila Rossi Batista, Fabiana Dayse Magalhães Siman, Dalton Valentim Vassallo, Alessandra Simão Padilha and Ivanita Stefanon
    Citation: Lipids in Health and Disease 2010 9:53
    Content type: Research Published on:

  4. The Friedewald formula (FF) is useful for calculating serum low-density lipoprotein cholesterol (LDL-C) values, but has a remarkable deviation and limitation especially in hypertriglyceridemia. We modify the f...

    Authors: Yunqin Chen, Xiaojin Zhang, Baishen Pan, Xuejuan Jin, Haili Yao, Bin Chen, Yunzeng Zou, Junbo Ge and Haozhu Chen
    Citation: Lipids in Health and Disease 2010 9:52
    Content type: Short paper Published on:

  5. The effects of hypercholesterolemia on vasomotricity in apolipoprotein E-deficient (ApoE) mice, a murine model of spontaneous atherosclerosis, are still unclear. The studies were mostly performed in conductanc...

    Authors: Maine S Cola, Agata L Gava, Silvana S Meyrelles and Elisardo C Vasquez
    Citation: Lipids in Health and Disease 2010 9:51
    Content type: Short paper Published on:

  6. Oxidative stress is supposed to increase lipid accumulation by stimulation of hepatic lipogenesis at transcriptional level. This study was performed to investigate the role of glutathione in the regulation of ...

    Authors: Corinna Brandsch, Tobias Schmidt, Diana Behn, Kristin Weiße, Andreas S Mueller and Gabriele I Stangl
    Citation: Lipids in Health and Disease 2010 9:50
    Content type: Research Published on:

  7. The novel compound 1a is one of the isoflavone fatty acid esters. In order to investigate the anti-obesity effect of compound 1a and its potential mechanism of influence in adipocyte differentiation, Obese male C...

    Authors: Yao Yao, Xiao-Bo Li, Wei Zhao, Yan-Yan Zeng, Hong Shen, Hua Xiang and Hong Xiao
    Citation: Lipids in Health and Disease 2010 9:49
    Content type: Research Published on:

  8. Apolipoprotein B (apoB) containing lipoproteins, i.e. VLDL, LDL and Lp(a), are consequently lowered by ACTH treatment in humans. This is also seen as reduced plasma apoB by 20-30% and total cholesterol by 30-4...

    Authors: Maria Skoog, Maria Berggren-Söderlund, Peter Nilsson-Ehle and Ning Xu
    Citation: Lipids in Health and Disease 2010 9:48
    Content type: Research Published on:

  9. Endocannabinoids (eCBs) are ubiquitous lipid mediators that act on specific (CB1, CB2) and non-specific (TRPV1, PPAR) receptors. Despite many experimental animal studies proved eCB involvement in the pathogene...

    Authors: Marcello Naccarato, Daniela Pizzuti, Stefania Petrosino, Marco Simonetto, Laura Ferigo, Fabio Chiodo Grandi, Gilberto Pizzolato and Vincenzo Di Marzo
    Citation: Lipids in Health and Disease 2010 9:47
    Content type: Research Published on:

  10. Paraoxonase-1 (PON1), a lactonase synthesized by the liver, circulates in blood bound to high-density lipoproteins (HDL). This enzyme is thought to degrade oxidized phospholipids and play an important role in ...

    Authors: Judit Marsillach, Gerard Aragonès, Bharti Mackness, Michael Mackness, Anna Rull, Raúl Beltrán-Debón, Juan Pedro-Botet, Carlos Alonso-Villaverde, Jorge Joven and Jordi Camps
    Citation: Lipids in Health and Disease 2010 9:46
    Content type: Research Published on:

  11. The body mass index (BMI) is the most commonly used marker for evaluating obesity related risks, however, central obesity measures have been proposed to be more informative. Lipid accumulation product (LAP) is...

    Authors: Mohammadreza Bozorgmanesh, Farzad Hadaegh and Fereidoun Azizi
    Citation: Lipids in Health and Disease 2010 9:45
    Content type: Research Published on:

  12. Piper sarmentosum (P.s) has flavonoid component in its leaves which has antioxidative effect. To date, its effect on atherosclerosis has not been studied histologically.

    Authors: Adel A Amran, Zaiton Zakaria, Faizah Othman, Srijit Das, Santhana Raj and Nor-Anita M M Nordin
    Citation: Lipids in Health and Disease 2010 9:44
    Content type: Research Published on:

  13. The endocannabinoids, anandamide and 2-AG, are produced by adipocytes, where they stimulate lipogenesis via cannabinoid CB1 receptors and are under the negative control of leptin and insulin. Endocannabinoid leve...

    Authors: Giovanni Annuzzi, Fabiana Piscitelli, Lucrezia Di Marino, Lidia Patti, Rosalba Giacco, Giuseppina Costabile, Lutgarda Bozzetto, Gabriele Riccardi, Roberta Verde, Stefania Petrosino, Angela A Rivellese and Vincenzo Di Marzo
    Citation: Lipids in Health and Disease 2010 9:43
    Content type: Research Published on:

  15. In this study we aimed to assess lipid peroxidation during carotid endarterectomy by the formation of PUFA hydroperoxides (PUFAHP) and isoprostanes (IP) and concomitant peroxisomal beta-oxidation as a physiolo...

    Authors: Sebastiano Banni, Roberto Montisci, Roberto Sanfilippo, Gabriele Finco, Daniela Sanna, Elena Giordano, Elisabetta Murru, Lina Cordeddu, Gianfranca Carta, Donata Banni and Antonio Marchi
    Citation: Lipids in Health and Disease 2010 9:41
    Content type: Research Published on:

  17. There are many reports about the anti-arrhythmic effects of ω-3 polyunsaturated fatty acids, however, the mechanisms are still not completely delineated. The purpose of this study was to investigate the charac...

    Authors: Ru-xing Wang, Xiao-rong Li, Tao Guo, Li-ping Sun, Su-xia Guo, Zhen-Yu Yang, Xiang-Jun Yang and Wen-ping Jiang
    Citation: Lipids in Health and Disease 2010 9:39
    Content type: Research Published on:

  18. Dexamethasone (DEX) is known to induce diabetes and dyslipidemia. We have compared fasting triacylglycerol and cholesterol concentrations across 20 lipoprotein fractions and glucose tolerance in control (stand...

    Authors: Michaela Krupková, Lucie Šedová, František Liška, Drahomíra Křenová, Vladimír Křen and Ondřej Šeda
    Citation: Lipids in Health and Disease 2010 9:38
    Content type: Short paper Published on:

  19. Chicken meat with reduced concentration of arachidonic acid (AA) and reduced ratio between omega-6 and omega-3 fatty acids has potential health benefits because a reduction in AA intake dampens prostanoid signali...

    Authors: Anna Haug, Ingrid Olesen and Olav A Christophersen
    Citation: Lipids in Health and Disease 2010 9:37
    Content type: Research Published on:

  20. Adipocytes contribute to inflammation and the innate immune response through expression of inflammatory mediators. High levels of these mediators have been related to chronic inflammation state and insulin res...

    Authors: Aurelio Ocaña, Cristina Gómez-Asensio, Elena Arranz-Gutiérrez, Carlos Torres, Francisco Javier Señoráns and Guillermo Reglero
    Citation: Lipids in Health and Disease 2010 9:36
    Content type: Research Published on:

  21. Oxidative damage has been proposed as a possible mechanism involved in lead toxicity, specially affecting the liver and kidney. Previous studies have shown the antioxidant effect of Spirulina maxima in several ex...

    Authors: Johny C Ponce-Canchihuamán, Oscar Pérez-Méndez, Rolando Hernández-Muñoz, Patricia V Torres-Durán and Marco A Juárez-Oropeza
    Citation: Lipids in Health and Disease 2010 9:35
    Content type: Research Published on:

  22. Serum apolipoprotein (apo) A-I was considered to be an immune regulator and could suppress pro-inflammatory cytokines generated by activated T cell in some autoimmune diseases. However, the change of serum apo...

    Authors: Bin Zhang, ShuXiang Pu, BinMei Li, JianRui Ying, Xing Wang Song and Cong Gao
    Citation: Lipids in Health and Disease 2010 9:34
    Content type: Research Published on:

  23. The alkylphospholipid analog miltefosine (hexadecylphosphocholine) is a membrane-directed antitumoral and antileishmanial drug belonging to the alkylphosphocholines, a group of synthetic antiproliferative agen...

    Authors: José M Jiménez-López, Pablo Ríos-Marco, Carmen Marco, Josefa L Segovia and María P Carrasco
    Citation: Lipids in Health and Disease 2010 9:33
    Content type: Review Published on:

  24. Paraoxonase-1 (PON1) is an antioxidant enzyme that attenuates the production of the monocyte chemoattractant protein-1 (MCP-1) in vitro. Although oxidation and inflammation are closely related processes, the asso...

    Authors: Sandra Parra, Judit Marsillach, Gerard Aragonès, Anna Rull, Raúl Beltrán-Debón, Carlos Alonso-Villaverde, Jorge Joven and Jordi Camps
    Citation: Lipids in Health and Disease 2010 9:32
    Content type: Short paper Published on:

  25. Results from increasing numbers of in vitro and in vivo studies have demonstrated that omega 3 fatty acids incorporated in cell culture media or in the diet of the animals can suppress the growth of cancers. When...

    Authors: Theodore R Witte, Alexander J Salazar, Oscar F Ballester and W Elaine Hardman
    Citation: Lipids in Health and Disease 2010 9:31
    Content type: Research Published on:

  26. Dietary fats have long been associated with human health, and especially cardiovascular disease (CVD). Some observational studies have shown that reduction in dietary fats, and particularly cholesterol is asso...

    Authors: Evangelos Polychronopoulos, George Pounis, Vassiliki Bountziouka, Akis Zeimbekis, Ioanna Tsiligianni, Brikena-Eirini Qira, Efthimios Gotsis, George Metallinos, Christos Lionis and Demosthenes Panagiotakos
    Citation: Lipids in Health and Disease 2010 9:30
    Content type: Short paper Published on:

  27. We recently examined the distribution of abdominal fat, dietary intake and biochemical data in patients with nonalcoholic fatty liver disease (NAFLD) and found that non-obese NAFLD patients did not necessarily...

    Authors: Munechika Enjoji, Kazuyuki Machida, Motoyuki Kohjima, Masaki Kato, Kazuhiro Kotoh, Kazuhisa Matsunaga, Manabu Nakashima and Makoto Nakamuta
    Citation: Lipids in Health and Disease 2010 9:29
    Content type: Short paper Published on:

  28. The association between -250G>A polymorphism in the promoter region of the hepatic lipase gene (LIPC) and plasma high-density lipoprotein cholesterol (HDL-C) concentration is contradictory in diverse ethnics. Bai...

    Authors: Li Meng, Yin Ruixing, Li Yiyang, Long Xingjiang, Li Kela, Liu Wanying, Zhang Lin, Lin Weixiong, Yang Dezhai and Pan Shangling
    Citation: Lipids in Health and Disease 2010 9:28
    Content type: Research Published on:

  29. Friedewald's formula for the estimation of LDL-C concentration is the most often used formula in clinical practice. A recent formula by Anandaraja and colleagues for LDL-C estimation still needs to be evaluate...

    Authors: Ana Vujovic, Jelena Kotur-Stevuljevic, Slavica Spasic, Nada Bujisic, Jelena Martinovic, Milica Vujovic, Vesna Spasojevic-Kalimanovska, Aleksandra Zeljkovic and Dragoljub Pajic
    Citation: Lipids in Health and Disease 2010 9:27
    Content type: Research Published on:

  30. The most important function of collagen and elastin is to induce several mechanical parameters which are known to play a dominant role in governing mechanical properties of the blood vessels. The aortic tissue...

    Authors: Mohamed Anwar K Abdelhalim, N J Siddiqi, AS Alhomida and Mohammed S Al-Ayed
    Citation: Lipids in Health and Disease 2010 9:26
    Content type: Research Published on:

  31. Nonalcoholic fatty liver disease is the most common chronic liver disease in the world, and is becoming increasingly prevalent. Saponins of sea cucumber (SSC) are proven to exhibit various biological activitie...

    Authors: Xiao-Qian Hu, Yu-Ming Wang, Jing-Feng Wang, Yong Xue, Zhao-Jie Li, Koji Nagao, Teruyoshi Yanagita and Chang-Hu Xue
    Citation: Lipids in Health and Disease 2010 9:25
    Content type: Research Published on:

  32. fatty acids are considered to be effective components to promote wound healing and Lucilia sericata larvae are applied clinically to treat intractable wounds. We aimed to investigat the effect of fatty acid extra...

    Authors: Zhen Zhang, Shouyu Wang, Yunpeng Diao, Jianing Zhang and Decheng Lv
    Citation: Lipids in Health and Disease 2010 9:24
    Content type: Research Published on:

  33. There is an increasing number of novel antilipidemic therapies under consideration. The putative hypolipidemic effect of N-acetylcysteine (NAC) and sesame oil was studied in a mouse model of dietary-induced hy...

    Authors: Laskarina-Maria Korou, George Agrogiannis, Alkisti Pantopoulou, Ioannis S Vlachos, Dimitrios Iliopoulos, Theodoros Karatzas and Despoina N Perrea
    Citation: Lipids in Health and Disease 2010 9:23
    Content type: Research Published on:

  35. The aim of the study was to assess the influence of co-existing atrial fibrillation (AF) on inflammatory condition factors, left ventricular function, clinical course and the efficacy of statin treatment of co...

    Authors: Agata Bielecka-DÄ…browa, Jan Henryk Goch, Jacek Rysz, Marek Maciejewski, Ravi Desai, Wilbert S Aronow and Maciej Banach
    Citation: Lipids in Health and Disease 2010 9:21
    Content type: Research Published on:

  36. LeptiCore® is a proprietary combination of various ingredients which have been shown to have properties which could be beneficial to weight loss in obese and overweight human subjects. This study evaluates the ef...

    Authors: Dieudonne Kuate, Blanche C O Etoundi, Boris K G Azantsa, Anne-Pascale N Kengne, Judith L Ngondi and Julius E Oben
    Citation: Lipids in Health and Disease 2010 9:20
    Content type: Research Published on:

  37. Multiple Sclerosis (MS) patients present a decrease of antioxidants and neuroprotective and immunoregulatory vitamins and an increase of total homocysteine (tHcy), cholesterol (CHL), HDL-cholesterol, and of ce...

    Authors: Giuseppe Salemi, Maria Concetta Gueli, Francesco Vitale, Floriana Battaglieri, Egidio Guglielmini, Paolo Ragonese, Angela Trentacosti, Maria Fatima Massenti, Giovanni Savettieri and Antonino Bono
    Citation: Lipids in Health and Disease 2010 9:19
    Content type: Short paper Published on:

  38. Obesity increases the risk for insulin resistance and metabolic syndrome in both adults and children. FABP4 is a member of the intracellular lipid-binding protein family that is predominantly expressed in adip...

    Authors: Abdelnaby Khalyfa, Bharat Bhushan, Mohamed Hegazi, Jinkwan Kim, Leila Kheirandish-Gozal, Rakesh Bhattacharjee, Oscar Sans Capdevila and David Gozal
    Citation: Lipids in Health and Disease 2010 9:18
    Content type: Research Published on:

  39. Cholesterol gallstone disease is a very common disease in both industrialized and developing countries. Many studies have found that cholesterol gallstones are more common in women than men. The molecular mech...

    Authors: Wei Cui, Zhao-Yan Jiang, Qu Cai, Ru-Yuan Zhang, Wei-Ze Wu, Jian-Cheng Wang, Jian Fei, Sheng-Dao Zhang and Tian-Quan Han
    Citation: Lipids in Health and Disease 2010 9:17
    Content type: Research Published on:

  40. Although its role to prevent secondary cardiovascular complications has been well established, how acetyl salicylic acid (ASA, aspirin) regulates certain key molecules in the atherogenesis is still not known. ...

    Authors: Li Lu, Hong Liu, Jiahe Peng, Lin Gan, Lili Shen, Qian Zhang, Liangpeng Li, Li Zhang, Chang Su and Yu Jiang
    Citation: Lipids in Health and Disease 2010 9:16
    Content type: Research Published on:

  41. Sphingolipids are essential components of cell membranes, and many of them regulate vital cell functions. In particular, ceramide plays crucial roles in cell signaling processes. Two major actions of ceramides...

    Authors: Lide Arana, Patricia Gangoiti, Alberto Ouro, Miguel Trueba and Antonio Gómez-Muñoz
    Citation: Lipids in Health and Disease 2010 9:15
    Content type: Review Published on:

  42. Chronic inflammations, atherosclerosis and obesity, are major risk factors for cardiovascular diseases. Immune modulation of the inflammatory response has shown promise in animal models of atherogenesis and me...

    Authors: Aldar S Bourinbaiar and Vichai Jirathitikal
    Citation: Lipids in Health and Disease 2010 9:14
    Content type: Research Published on:

  44. Acute and chronic inflammation play essential roles in inflammatory/autoimmune conditions. Protective anti-inflammatory effects of the n-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)...

    Authors: Weimin Kong, Jui-Hung Yen, Evros Vassiliou, Sabina Adhikary, Miguel G Toscano and Doina Ganea
    Citation: Lipids in Health and Disease 2010 9:12
    Content type: Research Published on:

  46. Exaggerated postprandial spikes in blood glucose and lipids induce proportional increases in oxidative stress, which acutely trigger impairment endothelial, inflammation and increased risk of future cardiovasc...

    Authors: Mahbubeh Setorki, Sedighe Asgary, Akram Eidi, Ali Haeri rohani and Majid KHazaei
    Citation: Lipids in Health and Disease 2010 9:10
    Content type: Research Published on:

  47. Polysaccharide from fuzi (FPS), a Chinese herbal medicine extract, has been demonstrated to exert lipid lowering affects. In this study we examined potential mechanisms underlying this affect, specifically alt...

    Authors: Xiongqing Huang, Juan Tang, Qin Zhou, Hanping Lu, Yiling Wu and Weikang Wu
    Citation: Lipids in Health and Disease 2010 9:9
    Content type: Research Published on:

  48. Apolipoprotein E is a polymorphic and multifunctional protein with numerous roles in lipoprotein metabolism. The three common isoforms apoE2, apoE3 and apoE4 show isoform-specific functional properties includi...

    Authors: Inga Kuhlmann, Anne Marie Minihane, Patricia Huebbe, Almut Nebel and Gerald Rimbach
    Citation: Lipids in Health and Disease 2010 9:8
    Content type: Review Published on:

  49. Omega-3 and -6 polyunsaturated fatty acids (LCPUFA), are important for good health conditions. They are present in membrane phospholipids.

    Authors: Angela M Rizzo, Gigliola Montorfano, Manuela Negroni, Laura Adorni, Patrizia Berselli, Paola Corsetto, Klaus Wahle and Bruno Berra
    Citation: Lipids in Health and Disease 2010 9:7
    Content type: Research Published on:

  50. The present study examined plasma lipid profiles in thirty patients suffered from acute viral hepatitis. Patients' blood samples were collected at both the debut and recovery of diseases. Thirty sex and age ma...

    Authors: Libo Luo, Xiangke Pu, Yongzhong Wang and Ning Xu
    Citation: Lipids in Health and Disease 2010 9:5
    Content type: Research Published on:
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Lipids in Health and Disease

ISSN: 1476-511X