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  1. Research

    The association of lipid metabolism relative gene polymorphisms and ischemic stroke in Han and Uighur population of Xinjiang

    The present study is aimed to evaluate difference of lipid metabolism related gene single nucleotide polymorphisms (SNPs) with ischemic stroke (IS) in Han and Uighur population of Xinjiang, China.

    Yun-hua Yue, Ling-yun Liu, Liang Hu, You-mei Li, Jie-ping Mao, Xiao-ying Yang and Na-mu Dila

    Lipids in Health and Disease 2017 16:120

    Published on: 17 June 2017

  2. Research

    Efficacy and safety of alirocumab in patients with hypercholesterolemia not adequately controlled with non-statin lipid-lowering therapy or the lowest strength of statin: ODYSSEY NIPPON study design and rationale

    Statins are generally well-tolerated and serious side effects are infrequent, but some patients experience adverse events and reduce their statin dose or discontinue treatment altogether. Alirocumab is a highl...

    Tamio Teramoto, Akira Kondo, Arihiro Kiyosue, Mariko Harada-Shiba, Yasushi Ishigaki, Kimimasa Tobita, Yumiko Kawabata, Asuka Ozaki, Marie T. Baccara-Dinet and Masataka Sata

    Lipids in Health and Disease 2017 16:121

    Published on: 17 June 2017

  3. Research

    The elevation of plasma concentrations of apoB-48-containing lipoproteins in familial hypercholesterolemia is independent of PCSK9 levels

    Previous studies have reported high plasma concentrations of both intestinal apolipoprotein (apo) B-48-containing lipoproteins and PCSK9 in subjects with familial hypercholesterolemia (FH). However, the extent...

    Jean-Philippe Drouin-Chartier, Jean-Charles Hogue, André J. Tremblay, Jean Bergeron, Benoît Lamarche and Patrick Couture

    Lipids in Health and Disease 2017 16:119

    Published on: 15 June 2017

  4. Research

    Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress

    Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation. The aim of this study was t...

    Daniel Medina-Luna, Mónica Guadalupe Santamaría-Olmedo, Yessica Zamudio-Cuevas, Karina Martínez-Flores, Javier Fernández-Torres, Gabriela Angélica Martínez-Nava, Denise Clavijo-Cornejo, Cristina Hernández-Díaz, Anell Olivos-Meza, Luis Enrique Gomez-Quiroz, María Concepción Gutiérrez-Ruiz, Carlos Pineda, Francisco Blanco, Anthony M. Reginato and Alberto López-Reyes

    Lipids in Health and Disease 2017 16:114

    Published on: 12 June 2017

  5. Research

    What is the impact of PCSK9 rs505151 and rs11591147 polymorphisms on serum lipids level and cardiovascular risk: a meta-analysis

    PCSK9 rs505151 and rs11591147 polymorphisms are identified as gain- and loss-of-function mutations, respectively. The effects of these polymorphisms on serum lipid levels and cardiovas...

    Chengfeng Qiu, Pingyu Zeng, Xiaohui Li, Zhen Zhang, Bingjie Pan, Zhou Y. F. Peng, Yapei Li, Yeshuo Ma, Yiping Leng and Ruifang Chen

    Lipids in Health and Disease 2017 16:111

    Published on: 12 June 2017

  6. Research

    Effect of oral cinnamon intervention on metabolic profile and body composition of Asian Indians with metabolic syndrome: a randomized double -blind control trial

    Nutritional modulation remains central to the management of metabolic syndrome. Intervention with cinnamon in individuals with metabolic syndrome remains sparsely researched.

    Sonal Gupta Jain, Seema Puri, Anoop Misra, Seema Gulati and Kalaivani Mani

    Lipids in Health and Disease 2017 16:113

    Published on: 12 June 2017

  7. Research

    Severe hypertriglyceridemia in Norway: prevalence, clinical and genetic characteristics

    There is a lack of comprehensive patient-datasets regarding prevalence of severe hypertriglyceridemia (sHTG; triglycerides ≥10 mmol/L), frequency of co-morbidities, gene mutations, and gene characterization in...

    Kjetil Retterstøl, Ingunn Narverud, Randi Selmer, Knut E. Berge, Ingvild V. Osnes, Stine M. Ulven, Bente Halvorsen, Pål Aukrust, Kirsten B. Holven and Per O. Iversen

    Lipids in Health and Disease 2017 16:115

    Published on: 12 June 2017

  8. Research

    Enhancing the quality and lipid stability of chicken nuggets using natural antioxidants

    Current day consumers prefer natural antioxidants to synthetic antioxidants because they are more active. However, the activity generally depends on the specific condition and composition of food. The aim of t...

    Muhammad Sajid Arshad, Ali Imran, Muhammad Tahir Nadeem, Muhammad Sohaib, Farhan Saeed, Faqir Muhammad Anjum, Joong-Ho Kwon and Shahzad Hussain

    Lipids in Health and Disease 2017 16:108

    Published on: 8 June 2017

  9. Review

    Effects of oil quality and antioxidant supplementation on sow performance, milk composition and oxidative status in serum and placenta

    The aim of this study was to determine the effects of oil quality and antioxidant (AOX) supplementation on sow performance, milk composition and oxidative status.

    Guoqi Su, Junmei Zhao, Guangbo Luo, Yue Xuan, Zhengfeng Fang, Yan Lin, Shengyu Xu, De Wu, Jun He and Lianqiang Che

    Lipids in Health and Disease 2017 16:107

    Published on: 7 June 2017

  10. Research

    Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice

    Nonalcoholic fatty liver disease (NAFLD) is increasing worldwide as one of the leading causes of chronic liver disease. Sake lees (SL) are secondary products of sake manufacturing and are considered to have be...

    Hisako Kubo, Masato Hoshi, Takuya Matsumoto, Motoko Irie, Shin Oura, Hiroko Tsutsumi, Yoji Hata, Yasuko Yamamoto and Kuniaki Saito

    Lipids in Health and Disease 2017 16:106

    Published on: 3 June 2017

  11. Research

    Dietary supplementation with n-3-fatty acids in patients with pancreatic cancer and cachexia: marine phospholipids versus fish oil - a randomized controlled double-blind trial

    Like many other cancer patients, most pancreatic carcinoma patients suffer from severe weight loss. As shown in numerous studies with fish oil (FO) supplementation, a minimum daily intake of 1.5 g n-3-fatty ac...

    Kristin Werner, Daniela Küllenberg de Gaudry, Lenka A. Taylor, Tobias Keck, Clemens Unger, Ulrich T. Hopt and Ulrich Massing

    Lipids in Health and Disease 2017 16:104

    Published on: 2 June 2017

  12. Research

    Lactic-fermented egg white reduced serum cholesterol concentrations in mildly hypercholesterolemic Japanese men: a double-blind, parallel-arm design

    Lactic-fermented egg white (LE), produced by lactic acid fermentation of egg white, is an easy-to-consume form of egg white. Here we assessed the effect of daily consumption of LE for 8 weeks on serum total ch...

    Ryosuke Matsuoka, Mika Usuda, Yasunobu Masuda, Masaaki Kunou and Kazunori Utsunomiya

    Lipids in Health and Disease 2017 16:101

    Published on: 30 May 2017

  13. Research

    The cruciferous Diplotaxis simplex: Phytochemistry analysis and its protective effect on liver and kidney toxicities, and lipid profile disorders in alloxan-induced diabetic rats

    Type 2 diabetes mellitus is a prevalent systemic disease affecting an important proportion of the population worldwide. It has been suggested that excessive reactive oxygen species generation and therefore dev...

    Hamida Jdir, Rihab Ben Abdallah Kolsi, Sami Zouari, Khaled Hamden, Nacim Zouari and Nahed Fakhfakh

    Lipids in Health and Disease 2017 16:100

    Published on: 30 May 2017

  14. Review

    Punicic acid: A striking health substance to combat metabolic syndromes in humans

    Punicic acid, a bioactive compound of pomegranate seed oil has gained wide attention for their therapeutic potential. Different studies conducted on animal and human models have revealed that punicic acid is v...

    Muhmmad Asim Shabbir, Moazzam Rafiq Khan, Muhammad Saeed, Imran Pasha, Anees Ahmed Khalil and Naila Siraj

    Lipids in Health and Disease 2017 16:99

    Published on: 30 May 2017

  15. Research

    Fat content, fatty acid pattern and iron content in livers of turkeys with hepatic lipidosis

    The so-called “hepatic lipidosis” in turkeys is an acute progressive disease associated with a high mortality rate in a very short time. Dead animals show a massive fatty degeneration of the liver. The cause i...

    Christian Visscher, Lea Middendorf, Ronald Günther, Alexandra Engels, Christof Leibfacher, Henrik Möhle, Kristian Düngelhoef, Stefan Weier, Wolfram Haider and Dimitri Radko

    Lipids in Health and Disease 2017 16:98

    Published on: 30 May 2017

  16. Short report

    Emulsifying dietary fat modulates postprandial endotoxemia associated with chylomicronemia in obese men: a pilot randomized crossover study

    Postprandial hyperlipemia is recognized as a major cardio-metabolic risk factor, recently linked to the co-absorption of pro-inflammatory lipopolysaccharides with dietary lipids. This causes endotoxemia that i...

    Cécile Vors, Jocelyne Drai, Gaëlle Pineau, Martine Laville, Hubert Vidal, Fabienne Laugerette and Marie-Caroline Michalski

    Lipids in Health and Disease 2017 16:97

    Published on: 25 May 2017

  17. Research

    Glutamate excitotoxicity induced by orally administered propionic acid, a short chain fatty acid can be ameliorated by bee pollen

    Rodent models may guide investigations towards identifying either environmental neuro-toxicants or drugs with neuro-therapeutic effects. This work aims to study the therapeutic effects of bee pollen on brain g...

    Afaf El-Ansary, Huda S. Al-Salem, Alqahtani Asma and Abeer Al-Dbass

    Lipids in Health and Disease 2017 16:96

    Published on: 22 May 2017

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